ENANOMAPPER

eNanoMapper - A Database and Ontology Framework for Nanomaterials Design and Safety Assessment

Coordinatore	DOUGLAS CONNECT GMBH    more  Organization address address: BARMEGGENWEG 14 city: ZEININGEN postcode: 4314 contact info Titolo: Dr. Nome: Barry Cognome: Hardy Email: send email Telefono: 41618510170
Nazionalità Coordinatore	Switzerland [CH]
Sito del progetto	http://www.enanomapper.net
Totale costo	4˙998˙227 €
EC contributo	3˙996˙870 €
Programma	FP7-NMP Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies
Code Call	FP7-NMP-2013-SMALL-7
Funding Scheme	CP-FP
Anno di inizio	2014
Periodo (anno-mese-giorno)	2014-02-01   -   2017-01-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	DOUGLAS CONNECT GMBH  Organization address address: BARMEGGENWEG 14 city: ZEININGEN postcode: 4314 contact info Titolo: Dr. Nome: Barry Cognome: Hardy Email: send email Telefono: 41618510170	CH (ZEININGEN)	coordinator	765˙200.00
2	UNIVERSITEIT MAASTRICHT  Organization address address: Minderbroedersberg 4-6 city: MAASTRICHT postcode: 6200 MD contact info Titolo: Dr. Nome: Joseph Ih Cognome: Janssen Email: send email Telefono: 31433881961 Fax: 31433670286	NL (MAASTRICHT)	participant	800˙000.00
3	IN SILICO TOXICOLOGY GMBH  Organization address address: ALTKIRCHERSTRASSE 4 city: BASEL postcode: 4054 contact info Titolo: Dr. Nome: Christoph Cognome: Helma Email: send email Telefono: +41 774339164	CH (BASEL)	participant	519˙980.00
4	KAROLINSKA INSTITUTET  Organization address address: Nobels Vag 5 city: STOCKHOLM postcode: 17177 contact info Titolo: Mr. Nome: Per-Olof Cognome: Larsson Email: send email Telefono: +46 8 524 875 00 Fax: +46 8 33 69 81	SE (STOCKHOLM)	participant	413˙700.00
5	Teknologian tutkimuskeskus VTT Oy  Organization address address: Vuorimiehentie 3 city: Espoo postcode: 2150 contact info Titolo: Prof. Nome: Roland Cognome: Grafström Email: send email Telefono: +358 40 739 8443	FI (Espoo)	participant	397˙750.00
6	IDEACONSULT LIMITED LIABILITY COMPANY  Organization address address: ANGEL KANCHEV 4 city: SOFIA postcode: 1000 contact info Titolo: Dr. Nome: Luben Cognome: Boyanov Email: send email Telefono: +359 8 98427745 Fax: +359 2 9526265	BG (SOFIA)	participant	373˙840.00
7	EUROPEAN MOLECULAR BIOLOGY LABORATORY  Organization address address: Meyerhofstrasse 1 city: HEIDELBERG postcode: 69117 contact info Titolo: Dr. Nome: Phil Cognome: Irving Email: send email Telefono: +49 6221 387 8239 Fax: +49 6221 387 8301	DE (HEIDELBERG)	participant	372˙080.00
8	NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA  Organization address address: HEROON POLYTECHNIOU 9 ZOGRAPHOU CAMPUS city: ATHINA postcode: 15780 contact info Titolo: Ms. Nome: Georgia Cognome: Mertzelou Email: send email Telefono: 302108000000 Fax: 302108000000	EL (ATHINA)	participant	354˙320.00
9	TEKNOLOGIAN TUTKIMUSKESKUS VTT  Organization address address: TEKNIIKANTIE 4 A city: ESPOO postcode: 02044 VTT contact info Titolo: Prof. Nome: Roland Cognome: Grafström Email: send email Telefono: +358 40 739 8443	FI (ESPOO)	participant	0.00

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 Obiettivo del progetto (Objective)

'eNanoMapper will develop a data management and analysis infrastructure together with ontologies supporting the safety assessment activities of the European Nanomaterials research and development community. The project will address the requirements of safety assessment of nanomaterials by providing databases, analysis tools and ontologies for risk assessment and linking them with existing resources in this area.

The project plan involves close cooperation with NanoSafety Cluster members and other international organisations such as OECD, ISO/CEN, EC JRC, and EChA. Their requirements will guide the development of tools for experimental design, model building, and meta analysis across multiple datasets.

An ontology for nanomaterials will be developed to provide the following features: annotation of nanostructures and relevant biological properties, annotation of experimental model systems (e.g. cell lines), conditions, and protocols, complex search and reasoning capabilities, and the integration of data from existing nanotoxicology sources.

Systematic physicochemical, geometrical, structural, and biological studies of nanomaterials are nearly absent in the public domain. The establishment of a universal standardisation schema and infrastructure for nanomaterials safety assessment is a key project goal. It should catalyze collaboration, integrated analysis, and discoveries from data organised within a knowledge-based framework. It will support the discovery of nanomaterial properties responsible for toxicity, the identification of toxicity pathways and nano-bio interactions from linked datasets, ontologies, omics data and external data sources.

By interfacing with statistical and data mining tools we will be able to provide scientifically sound guidelines for experimental design as well as computational models for predicting nanotoxicity. These computational models will help to design safe nanomaterials and improve the risk assessment of existing nanoparticles.'