SYMUNITY

"Function of SymRK, a key protein for microbial accommodation in plants roots"

 Coordinatore THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE 

 Organization address address: The Old Schools, Trinity Lane
city: CAMBRIDGE
postcode: CB2 1TN

contact info
Titolo: Ms.
Nome: Renata
Cognome: Shaeffer
Email: send email
Telefono: +44 1223 333 543
Fax: +44 1223 332 988

 Nazionalità Coordinatore United Kingdom [UK]
 Totale costo 231˙283 €
 EC contributo 231˙283 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2013-IEF
 Funding Scheme MC-IEF
 Anno di inizio 2014
 Periodo (anno-mese-giorno) 2014-04-01   -   2016-03-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE

 Organization address address: The Old Schools, Trinity Lane
city: CAMBRIDGE
postcode: CB2 1TN

contact info
Titolo: Ms.
Nome: Renata
Cognome: Shaeffer
Email: send email
Telefono: +44 1223 333 543
Fax: +44 1223 332 988

UK (CAMBRIDGE) coordinator 231˙283.20

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

root    microbial    interactions    signals    signalling    pathogenic    gene    symbiotic    plant    residing    environment    soil    microbes    mycorrhizal    palmivora    colonization    symrk   

 Obiettivo del progetto (Objective)

'Plant roots interact with a huge diversity of soil residing microbes that improve or hamper plant development. In a changing agriculture, where chemical inputs have to be reduced to protect the environment, the use of beneficial microbes residing in soil to improve plant nutrition and to prevent diseases is a promising alternative. However, symbiotic and pathogenic microbes follow similar steps to colonize their hosts and little is known about the extent of commonalities in plant responses guiding outcome of these associations. A cornerstone in regulation of these processes is the perception of microbial derived signals. Several genes required for sensing of mycorrhizal symbionts and subsequent colonization have been shown to affect interaction with root pathogens. We recently demonstrated in Dr. Schornack’s lab that a mutant of SymRK receptor which is unable to develop mycorrhization show extensive colonization by the root pathogenic oomycete Phytophthora palmivora. As this gene is the most upstream element in the signalling cascade required for mycorrhiza, we can now hypothesize an unsuspected convergence of early signalling events relayed and integrated by this protein to promote microbial accommodation or rejection. I will decipher how SymRK exerts roles in both interactions using a combination of approaches consisting of phenotyping of SymRK knock-out and overexpressing plants challenged with P. palmivora, mycorrhizal fungi and their isolated molecular signatures. The SymRK dependent transcriptomes in response to symbiotic or pathogenic signals and to the invasion will be elucidated to get clues about the gene network downstream of SymRK controlling synergistically or antagonistically these interactions. Finally I will take advantage of my environment in the Sainsbury Laboratory of Cambridge University to perform cutting edge microscopy on the cellular dynamics of receptors required for symbiosis including SymRK.'

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