VASCUBONE

Construction kit for tailor-made vascularized boneimplants

 Coordinatore FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V 

 Organization address address: Hansastrasse 27C
city: MUENCHEN
postcode: 80686

contact info
Titolo: Mr.
Nome: Christoph
Cognome: Schulte
Email: send email
Telefono: +49 89 1205 2728
Fax: +49 89 1205 7534

 Nazionalità Coordinatore Germany [DE]
 Totale costo 15˙569˙959 €
 EC contributo 11˙966˙071 €
 Programma FP7-HEALTH
Specific Programme "Cooperation": Health
 Code Call FP7-HEALTH-2009-single-stage
 Funding Scheme CP-IP
 Anno di inizio 2010
 Periodo (anno-mese-giorno) 2010-01-01   -   2015-03-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V

 Organization address address: Hansastrasse 27C
city: MUENCHEN
postcode: 80686

contact info
Titolo: Mr.
Nome: Christoph
Cognome: Schulte
Email: send email
Telefono: +49 89 1205 2728
Fax: +49 89 1205 7534

DE (MUENCHEN) coordinator 2˙380˙655.59
2    JULIUS-MAXIMILIANS UNIVERSITAET WUERZBURG

 Organization address address: SANDERRING 2
city: WUERZBURG
postcode: 97070

contact info
Titolo: Mr.
Nome: Christian
Cognome: Gloggengiesser
Email: send email
Telefono: +49 931 3182294
Fax: +49 931 3187180

DE (WUERZBURG) participant 1˙816˙592.00
3    MEDIZINISCHE UNIVERSITAET INNSBRUCK

 Organization address address: Christoph-Probst Platz 1
city: INNSBRUCK
postcode: 6020

contact info
Titolo: Prof.
Nome: Frank
Cognome: Kloss
Email: send email
Telefono: +43 512 504 81144
Fax: +43 512 504 24371

AT (INNSBRUCK) participant 1˙172˙180.00
4    UNIVERSITETET I BERGEN

 Organization address address: Museplassen 1
city: BERGEN
postcode: 5007

contact info
Titolo: Ms.
Nome: Inger
Cognome: Gjesdahl
Email: send email
Telefono: +47 55584980
Fax: +47 55584991

NO (BERGEN) participant 1˙082˙480.00
5    MRB Forschungszentrum fur Magnet-Resonanz-Bayern e.V.

 Organization address address: Am Hubland
city: Wuerzburg
postcode: 97074

contact info
Titolo: Dr.
Nome: Karl-Heinz
Cognome: Hiller
Email: send email
Telefono: +49 931 31 83060
Fax: +49 931 888 4680

DE (Wuerzburg) participant 898˙500.00
6    MEDICYTE GMBH

 Organization address address: Im Neuenheimer Feld 581
city: Heidelberg
postcode: 69120

contact info
Nome: Stefan
Cognome: Holder
Email: send email
Telefono: +49 6221 7292530
Fax: +49 6221 7292531

DE (Heidelberg) participant 742˙000.00
7    KUNGLIGA TEKNISKA HOEGSKOLAN

 Organization address address: Valhallavaegen 79
city: STOCKHOLM
postcode: 10044

contact info
Titolo: Ms.
Nome: Maria
Cognome: Andersz
Email: send email
Telefono: +46 8 7908277

SE (STOCKHOLM) participant 597˙280.00
8    NANOPET PHARMA GMBH

 Organization address address: Robert-Koch-Platz 4
city: Berlin
postcode: 10115

contact info
Titolo: Ms.
Nome: Nicole
Cognome: Gärtner
Email: send email
Telefono: +49 30 8904974 12
Fax: +49 30 8904974 99

DE (Berlin) participant 528˙156.00
9    PP-POLYMER AB

 Organization address address: KROSSGATAN 15
city: VALLINGBY
postcode: 162 50

contact info
Titolo: Mrs.
Nome: Ann-Christin
Cognome: Paul
Email: send email
Telefono: +46 8 4455300
Fax: +46 8 4455309

SE (VALLINGBY) participant 431˙899.00
10    DIACOATING GMBH

 Organization address address: MITTERWEG 24
city: INNSBRUCK
postcode: 6020

contact info
Titolo: Mr.
Nome: Armin
Cognome: Partl
Email: send email
Telefono: 4369920000000

AT (INNSBRUCK) participant 374˙926.00
11    KOMET RHOBEST GMBH

 Organization address address: Exlgasse 20a
city: Innsbruck
postcode: 6020

contact info
Titolo: Dr.
Nome: Doris
Cognome: Steinmüller-Nethl
Email: send email
Telefono: +43 512 283559 11
Fax: +43 512 283559 99

AT (Innsbruck) participant 367˙981.00
12    TOPASS GMBH

 Organization address address: DRAKESTRASSE 42
city: Berlin
postcode: 12205

contact info
Titolo: Ms.
Nome: Jutta
Cognome: Vom Brocke
Email: send email
Telefono: +49 30 8500980
Fax: +49 30 85009898

DE (Berlin) participant 364˙272.00
13    UPPSALA UNIVERSITET

 Organization address address: SANKT OLOFSGATAN 10 B
city: UPPSALA
postcode: 751 05

contact info
Titolo: Prof.
Nome: Karin
Cognome: Larsson
Email: send email
Telefono: +46 18 4713750
Fax: +46 18 513548

SE (UPPSALA) participant 357˙680.00
14    OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN

 Organization address address: DR. IGNAZ SEIPEL-PLATZ 2
city: WIEN
postcode: 1010

contact info
Titolo: Dr.
Nome: Günter
Cognome: Lepperdinger
Email: send email
Telefono: +43 512 58391940
Fax: +43 512 5839198

AT (WIEN) participant 327˙667.86
15    UNIVERSITAET INNSBRUCK

 Organization address address: INNRAIN 52
city: INNSBRUCK
postcode: 6020

contact info
Titolo: Dr.
Nome: Günter
Cognome: Lepperdinger
Email: send email
Telefono: +43 512 507 50840
Fax: +43 512 507 50899

AT (INNSBRUCK) participant 261˙757.14
16    JOHNSON & JOHNSON MEDICAL GMBH

 Organization address address: Robert Koch Strasse 1
city: Norderstedt
postcode: 22851

contact info
Titolo: Dr.
Nome: Juergen
Cognome: Trzewik
Email: send email
Telefono: +49 40 52975854
Fax: +49 40 5297 2 5854

DE (Norderstedt) participant 129˙883.00
17    EVONIK INDUSTRIES AG

 Organization address address: RELLINGHAUSER STRASSE 1-11
city: ESSEN
postcode: 45128

contact info
Titolo: Mr.
Nome: Thomas
Cognome: Rode
Email: send email
Telefono: +49 6181 59 3710
Fax: +49 6181 59 73710

DE (ESSEN) participant 80˙258.00
18    Nome Ente NON disponibile

 Organization address address: Uhlandstr. 16
city: Seligenstadt
postcode: 63500

contact info
Titolo: Dr.
Nome: Alexander
Cognome: Goetz
Email: send email
Telefono: +49 6182 6404755
Fax: +49 6182 640 47 56

DE (Seligenstadt) participant 51˙903.41

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

box    successful    regeneration    stem    efficacy    vivo    bone    regenerative    modification    defects    therapies    cell    types    clinical    biomaterials    tool   

 Obiettivo del progetto (Objective)

'The goal of VascuBone is to develop a “tool box” for bone regeneration, which on one hand fulfils basic requirements and on the other hand is freely combinable with what is needed in the respective patient’s situation. The tool box will include a variation of biocompatible biomaterials and cell types, FDA approved growth factors, material modification technologies, simulation and analytical tools like molecular imaging based in vivo diagnostics which can be combined for the specific medical need. This tool box will be used to develop translational approaches for regenerative therapies of three different types of bone defects. The chosen bone diseases differ in their requirements, to ensure a successful implementation and translation. Additionally this implementation strategy is characterized by high complexity to remove bottlenecks and limitations of bone regeneration identified in the clinical setting. Therefore definite quality criteria have to be evaluated concerning an optimal stem cell source/subpopulation as well as GF concentrations and their bioactivity in vivo. Furthermore quantitative evaluation will focus on the definition of differences between stem cell populations responsible for bone regeneration in young and old people, as a prerequisite for the development of regenerative therapies for the ageing European society. Considering a successful and prompt approval of the biomaterial, for each clinical application a minimum of modification steps in daily routine must be identified. The road map of the project and clinic trials contains pre-determined milestones, to ensure efficacy, safety, and immunological acceptance of the implant. The efficacy is quantified by high innovative MRI and PET/CT technology which is able to demonstrate the regenerative effect of biomaterials and cells in vivo. Based on the clinical data the proposal as “Advanced Therapeutical Medicinal Product” will be submitted to the European Medicines Agency at the end of the project.'

Introduzione (Teaser)

Regenerative medicine is a promising avenue for treating or repairing damaged tissues. A European consortium has decided to develop a 'toolbox' to engineer bone implants that can regenerate bone defects.

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