DISCHROM
Chromatin diseases: from basic mechanisms to therapy
| Coordinatore | CONSIGLIO NAZIONALE DELLE RICERCHE
Organization address
address: Piazzale Aldo Moro 7 contact info |
| Nazionalità Coordinatore | Italy [IT] |
| Totale costo | 2˙574˙827 € |
| EC contributo | 2˙574˙827 € |
| Programma | FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | FP7-PEOPLE-ITN-2008 |
| Funding Scheme | MC-ITN |
| Anno di inizio | 2009 |
| Periodo (anno-mese-giorno) | 2009-11-01 - 2013-10-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
CONSIGLIO NAZIONALE DELLE RICERCHE
Organization address
address: Piazzale Aldo Moro 7 contact info |
IT (ROMA) | coordinator | 564˙827.00 |
| 2 |
FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE
Organization address
address: AVENIDA GRAN VIA HOSPITALET 199-203 contact info |
ES (L'HOSPITALET DE LLOBREGAT) | participant | 380˙355.00 |
| 3 |
BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING
Organization address
address: Al. Fleming Street 34 contact info |
EL (VARI-ATHENS) | participant | 371˙880.00 |
| 4 |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Organization address
address: The Old Schools, Trinity Lane contact info |
UK (CAMBRIDGE) | participant | 219˙751.00 |
| 5 |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Organization address
address: University Offices, Wellington Square contact info |
UK (OXFORD) | participant | 213˙151.00 |
| 6 |
UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA
Organization address
address: VIA UNIVERSITA 4 contact info |
IT (MODENA) | participant | 212˙351.00 |
| 7 |
UNIVERSITE D'AIX MARSEILLE
Organization address
address: Boulevard Charles Livon 58 contact info |
FR (Marseille) | participant | 206˙452.00 |
| 8 |
UNIVERSITA DEGLI STUDI DELL'INSUBRIA
Organization address
address: Via Ravasi 2 contact info |
IT (VARESE) | participant | 205˙751.00 |
| 9 |
DIAGENODE
Organization address
address: RUE DU BOIS SAINT JEAN 3 LIEGE PARK SCIENCE contact info |
BE (SERAING) | participant | 200˙309.00 |
| 10 |
UNIVERSITE DE LA MEDITERRANEE D'AIX-MARSEILLE II
Organization address
address: Boulevard Charles Livon, Jardin du Pharo 58 contact info |
FR (MARSEILLE) | participant | 0.00 |
| 11 |
UNIVERSITY COLLEGE LONDON
Organization address
address: GOWER STREET contact info |
UK (LONDON) | participant | 0.00 |
Mappa
Word cloud
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Obiettivo del progetto (Objective)
'The scope of this ITN is to promote research and training in the field of chromatin diseases. Chromatin diseases (CD) are genetic pathologies resulting from mutations in structural components of chromatin or in enzymes that biochemically modify chromatin, altering chromatin status and thereby causing drastic effects on gene expression. CD frequency ranges from very rare to quite common pathologies; so far for the vast majority of them no treatment is as yet available. Molecular studies on these pathologies thus have a twofold value: to shed light on the intricate interplays between different levels of control of gene expression acting in the mammalian nucleus and to pave the way toward new and more effective strategies to approach the treatment of this increasing class of diseases. Our students will take advantage of the integrated approach on multilayered gene regulation, the multidisciplinary nature and the cutting-edge methodologies, which are an integral part of this proposal. We thus expect to provide a framework for the very high-level training of young researchers, receiving a strong backgrounds in molecular, cellular and developmental biology, genomics, bioinformatics, chromatin biology and epigenetics. Furthermore, they will develop expertise in many cutting edge methodologies and tools, such as imaging, high throughput gene technologies, ChIP. As a result, the ESRs will be highly competitive in performing independent research in various areas of biology and will represent a new breed of scientists trained in contemporary post-genomic biology using advanced technological tools to tackle human disease.'
Introduzione (Teaser)
Previously unaddressed chromatin diseases can now be tackled in a post-genomic era using new knowledge and methods. Training a new generation of researchers at a very high level will allow them to approach the treatment of chromatin diseases more efficiently.