ECOLASSA

Molecular and serological techniques to study Lassa virus ecology

Coordinatore	BERNHARD-NOCHT-INSTITUT FUER TROPENMEDIZIN    more  Organization address address: BERNHARD NOCHT STRASSE 74 city: HAMBURG postcode: 20359 contact info Titolo: Prof. Nome: Stephan Cognome: Günther Email: send email Telefono: 494043000000 Fax: 494043000000
Nazionalità Coordinatore	Germany [DE]
Totale costo	0 €
EC contributo	230˙288 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-IEF-2008
Funding Scheme	MC-IEF
Anno di inizio	2010
Periodo (anno-mese-giorno)	2010-05-01   -   2012-04-30

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	BERNHARD-NOCHT-INSTITUT FUER TROPENMEDIZIN  Organization address address: BERNHARD NOCHT STRASSE 74 city: HAMBURG postcode: 20359 contact info Titolo: Prof. Nome: Stephan Cognome: Günther Email: send email Telefono: 494043000000 Fax: 494043000000	DE (HAMBURG)	coordinator	230˙288.97

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 Obiettivo del progetto (Objective)

'Lassa fever is a zoonotic disease caused by Lassa virus. The disease is endemic in West Africa. Hemorrhagic courses of Lassa fever are associated with high mortality. It is estimated that 100,000 to 500,000 infections occur each year because of transmission of Lassa virus from its rodent reservoir (Mastomys natalensis) to human. Rodent control measures could reduce the risk of rodent-human transmission. However, the dynamics of virus-rodent interaction is poorly understood. This information is crucial to design efficient and cost-effective rodent control measures. Therefore, objective of the research project is to enhance knowledge on rodent ecology and molecular taxonomy as well as on microphylogeny, transmission, and persistence pattern of the virus in the rodent population. A second objective is the improvement of laboratory skills of the applicant in the area of virology and molecular biology to facilitate a multidisciplinary Lassa virus research linking rodent ecology, molecular epidemiology, diagnostics, and virology.'