ADAMS
Genomic variations underlying common behavior diseases and cognition trait in human populations
| Coordinatore | MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.
Organization address
address: Hofgartenstrasse 8 contact info |
| Nazionalità Coordinatore | Germany [DE] |
| Sito del progetto | http://genseq.molgen.mpg.de/cms/ |
| Totale costo | 5˙678˙333 € |
| EC contributo | 3˙000˙000 € |
| Programma | FP7-HEALTH
Specific Programme "Cooperation": Health |
| Code Call | FP7-HEALTH-2009-single-stage |
| Funding Scheme | CP-FP-SICA |
| Anno di inizio | 2009 |
| Periodo (anno-mese-giorno) | 2009-10-01 - 2012-09-30 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.
Organization address
address: Hofgartenstrasse 8 contact info |
DE (MUENCHEN) | coordinator | 618˙000.00 |
| 2 |
UNIVERSITAET BASEL
Organization address
address: Petersplatz 1 contact info |
CH (BASEL) | participant | 783˙000.00 |
| 3 |
KING'S COLLEGE LONDON
Organization address
address: Strand contact info |
UK (LONDON) | participant | 435˙000.00 |
| 4 |
UNIVERSITAETSKLINIKUM BONN
Organization address
address: Sigmund-Freud-Strasse 25 contact info |
DE (BONN) | participant | 393˙000.00 |
| 5 |
ZENTRALINSTITUT FUER SEELISCHE GESUNDHEIT
Organization address
address: Square J 5 contact info |
DE (MANNHEIM) | participant | 393˙000.00 |
| 6 |
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Organization address
address: 's Gravendijkwal 230 contact info |
NL (ROTTERDAM) | participant | 378˙000.00 |
| 7 |
"INSTITUTE OF BIOCHEMISTRY AND GENETICS, UFA SCIENTIFIC CENTRE OF RAS"
Organization address
address: Prospekt Oktyabrya 71 contact info |
RU (UFA) | participant | 0.00 |
| 8 |
ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY OF RUSSIAN ACADEMY
Organization address
address: VAVILOV 32 contact info |
RU (MOSCOW) | participant | 0.00 |
| 9 |
NATIONAL RESEARCH CENTER OF MENTAL HEALTH - RUSSIAN ACADEMY OF MEDICAL SCIENCES
Organization address
address: Kashirskoe sh 34 contact info |
RU (MOSCOW) | participant | 0.00 |
| 10 |
NII MEDICINSKOY GENETIKI TOMSKOGO NAUCHNOGO CENTRA SIBIRSKOGO OTDELENIYA ROSSIYSKOY AKADEMII MEDICINSKIH NAUK
Organization address
address: NABEREZHNAYA USHAYKI 10 contact info |
RU (TOMSK) | participant | 0.00 |
| 11 |
University Medicine OOO
Organization address
address: "Lomonosovsky prospect 31, bld. 5" contact info |
RU (Moscow) | participant | 0.00 |
| 12 |
Vavilov Institute of General Genetics - Russian Academy of Sciences
Organization address
address: Gubkin str. 3 contact info |
RU (Moscow) | participant | 0.00 |
Mappa
Word cloud
Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.
Obiettivo del progetto (Objective)
'The subject of the proposal is the search and analysis of genomic variations underlying Alzheimer's disease (AD), alcoholism and schizophrenia – wide-spread diseases in human populations. Schizophrenia and alcoholism are common forms of behavior pathology and disability in adult life. AD is a most common form of dementia in human populations. Though the genomic variations presumably associated with AD, alcoholism and schizophrenia were described in preliminary studies for European populations, the significance of the putatively associated alleles, genetic background as well as the role of environmental factors is still poorly understood for them. Within the framework of this project we plan to extend the studies of genomic variations underlying these diseases by performing genome-wide association analysis in cohorts of patients and normal individuals from several ethnic populations of Europe and Russia.The genetic factors for cognition endophenotype will also be studied. Candidate regions, both newly found and reported previously for these diseases will be additionally analyzed by sequencing. Such large scale population studies combined with deep analysis of particular genes and genomic regions will allow us to reveal genetic reasons for susceptibility to these diseases. On the basis of this research we propose to contribute to development of a diagnostic instrument for the analysis of genetic risk factors for AD, alcoholism and schizophrenia. Comparison of several ethnic cohorts (different populations from Russia and Central/Western and Southern Europe) will also help to elucidate the influence of genetic background and environmental factors on the etiology of neuropsychiatric diseases. Consortium includes 6 groups from EU/AC and 7 groups from Russia. The participants are leading specialists in their fields and have joint publications on subjects related to this proposal.'
Altri progetti dello stesso programma (FP7-HEALTH)
KIEKIDS (2011)
Development of an innovative paediatric formulation of an antiepileptic agent for the treatment of absence epilepsy in children
Read More