PLT

"PLETHORA transcriptions factors, new players in the control of phyllotaxis in Arabidopsis thaliana"

 Coordinatore UNIVERSITEIT UTRECHT 

 Organization address address: Heidelberglaan 8
city: UTRECHT
postcode: 3584 CS

contact info
Titolo: Ms.
Nome: Herminia
Cognome: Erasmo
Email: send email
Telefono: +31 30 2532614
Fax: -2531644

 Nazionalità Coordinatore Netherlands [NL]
 Totale costo 160˙748 €
 EC contributo 160˙748 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2009-IEF
 Funding Scheme MC-IEF
 Anno di inizio 2010
 Periodo (anno-mese-giorno) 2010-03-01   -   2012-02-29

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UNIVERSITEIT UTRECHT

 Organization address address: Heidelberglaan 8
city: UTRECHT
postcode: 3584 CS

contact info
Titolo: Ms.
Nome: Herminia
Cognome: Erasmo
Email: send email
Telefono: +31 30 2532614
Fax: -2531644

NL (UTRECHT) coordinator 160˙748.80

Mappa

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 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

pattern    plants    arabidopsis    proteins    impaired    apical    phyllotaxis    polar    regulatory    arising    organ    organs    function    genes    auxin    plt    mutant    pin    phyllotactic    family    roots    regulating    plant    model    meristem    zone    positioning    shoot   

 Obiettivo del progetto (Objective)

'The mathematical regularity of plant organ initiation, also known as phyllotaxis, has always intrigued mathematicians and botanists. Only recently was established that the plant hormone auxin has a major role in regulating organ positioning at the shoot apex of plants. Specific spatial accumulation of auxin induces organ formation and control organ spacing. The current model for phyllotaxis relies on polar auxin transport via auxin efflux facilitators of the PIN family, and postulated positive feedback loops between auxin and PIN proteins. However no regulatory mechanism and gene network have been proposed yet to explain how organ positioning is controlled in plants. The proposal aims to bridge this gap by using a unique genetic tool generated in the host laboratory, a mutant in the plant model Arabidopsis that switches from wild type spiral organ arrangement (organs arising by a divergent angle of 137.5º) to a decussate pattern (organs arising in opposite pairs). The mutant is impaired in three genes that belong to the PLETHORA (PLT) family genes previously described in roots as involved in a regulatory loop with auxin and PIN proteins to maintain an auxin gradient and root meristem function. This is the first time that a stable change in phyllotactic pattern has been observed in an Arabidopsis mutant, giving a real opportunity to understand regulatory mechanisms underlying behind this developmental process. The PLT genes impaired in this mutant are expressed throughout the shoot apical meristem, i.e. in the peripheral zone where are initiated organ primordia and in the central zone where are lying the stem cells, suggesting a role for PLT genes in establishment of phyllotactic patterns and in shoot apical meristem function. The aim of the project is to understand if PLT genes influence phyllotaxis by controlling auxin polar distribution, as in roots, or / and by regulating meristem size / organisation, the two parameters known to disturb organ positioning.'

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