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LuMaSense

A Non-Invasive Test for Guiding Follow–up of Patients with CT-Detected Lung Nodules

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 LuMaSense project word cloud

Explore the words cloud of the LuMaSense project. It provides you a very rough idea of what is the project "LuMaSense" about.

invasive    detected    optimization    alone    complexity    prototype    off    transfer    erc    economic    malignant    ip    urgent    complementary    operation    mortality    technique    health    noninvasive    specificity    96    screening    lc    cancer    spin    nodule    fund    rationale    marketable    treatment    clinical    diag    rate    oriented    delay    worldwide    programs    commercially    action    covered    idea    stages    tool    relies    auxiliary    positive    save    unnecessary    sensitivity    ct    undergone    16    poc    portability    false    conducting    combination    successful    exists    cancerous    costly    mature    placement    countries    lung    billion    distinguish    company    implication    healthcare    transform    evaluation    optimal    front    completing    powerful    stand    device    breath    plans    patients    speed    utilizing    immediately    usefulness    12    translated    grant    technological    ldct    group    24    care    morbidity    reduce    portfolio    competitors    market   

Project "LuMaSense" data sheet

The following table provides information about the project.

Coordinator
TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY 

Organization address
address: SENATE BUILDING TECHNION CITY
city: HAIFA
postcode: 32000
website: www.technion.ac.il

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Israel [IL]
 Total cost 150˙000 €
 EC max contribution 150˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-PoC
 Funding Scheme ERC-POC
 Starting year 2015
 Duration (year-month-day) from 2015-06-01   to  2016-11-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY IL (HAIFA) coordinator 150˙000.00

Map

 Project objective

This PoC is a commercially-oriented spin-off from our “DIAG-CANCER” ERC project, addressing an urgent clinical need in the field of lung cancer (LC). The rationale behind this PoC is that CT-based LC screening programs are emerging in many countries worldwide. However, the high false positive rate of this technique (96% out of the 24% positive CT findings are non-cancerous) has been a major challenge in front those plans. This is because the CT-detected non-cancerous group has undergone unnecessary invasive procedures that are both costly and associated with significant morbidity and mortality. With this PoC project, we aim to increase the specificity of the LDCT based screening program by utilizing an auxiliary noninvasive breath test to distinguish between malignant and non-cancerous CT findings. The proposed breath test relies on a novel stand-alone device that provide an improved combination of speed, sensitivity, portability, low complexity, easy operation and low production cost. In order to transform our idea and current technology into a marketable device we propose taking several steps: (i) optimization of a prototype device and evaluation of its clinical usefulness through clinical studies; (ii) completing the IP portfolio of the device; and (iii) conducting detailed market research to identify the optimal placement in the healthcare market and possible competitors. After completing these stages, to be covered by the present grant, we propose to proceed to the technology transfer to a mature health care company or through complementary fund to advance the technological plans. If successful, the proposed PoC can be translated immediately into a powerful tool for the management of nodule-positive patients. It will both reduce the rate of unnecessary invasive procedures, and on the other hand, will avoid treatment delay when cancer exists. The economic implication of this action is a significant save of ~$12-16 billion for the healthcare system worldwide.

 Publications

year authors and title journal last update
List of publications.
2016 Inbar Nardi-Agmon, Manal Abud-Hawa, Ori Liran, Naomi Gai-Mor, Maya Ilouze, Amir Onn, Jair Bar, Dekel Shlomi, Hossam Haick, Nir Peled
Exhaled Breath Analysis for Monitoring Response to Treatment in Advanced Lung Cancer
published pages: 827-837, ISSN: 1556-0864, DOI: 10.1016/j.jtho.2016.02.017
Journal of Thoracic Oncology 11/6 2019-07-22

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The information about "LUMASENSE" are provided by the European Opendata Portal: CORDIS opendata.

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