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SUPER-RESOL

Extracting Super-Resolution from Classical Fluorescence Microscopy

Total Cost €

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EC-Contrib. €

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Partnership

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Project "SUPER-RESOL" data sheet

The following table provides information about the project.

Coordinator
STICHTING VU 

Organization address
address: DE BOELELAAN 1105
city: AMSTERDAM
postcode: 1081 HV
website: www.vu.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 150˙000 €
 EC max contribution 150˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-PoC
 Funding Scheme ERC-POC
 Starting year 2014
 Duration (year-month-day) from 2014-12-01   to  2016-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    STICHTING VU NL (AMSTERDAM) coordinator 62˙500.00
2    COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES FR (PARIS 15) participant 87˙500.00

Map

 Project objective

The beginning of this century has seen the development of optical super-resolution fluorescence microscopic methods, which yield pictures to resolutions of a few tens of nanometers. This breakthrough has transformed the field of cellular biology, but relies on approaches generally demanding in terms of optics, and which can be applied only on limited classes of fluorophores. This project aims at preparing the commercialization of a new, simple, and cheap, way of extracting super-resolution from images obtained with classical confocal fluorescence microscopes. Currently, this approach yields images with a resolution between 80 nm to 50 nm, which can most likely be increased in a near future. This method can thus be used with any type of fluorophore, just by equipping (confocal) microscopes with a high-end X-Y table and a 2D detector. More complex super-resolution fluorescence microscopic techniques have generated more than 7000 citations in the last years, mostly in biology, but also in chemistry and material sciences. The proposed technology, which can i) easily be implemented for a limited cost and ii) requires no more maintenance and alignment than classical confocal microscopy, is expected to be rapidly implemented in a very large number of laboratories, thus generating new knowledge and a vast range of scientific advances. In the frame of this project, which is a direct consequence of the work started in the frame of the PhotProt ERC advanced grant (id n° 267333), we will in parallel i) improve the performances of this technology by modifying its present design, ii) perform the necessary patenting of this technology, iii) start market studies to evaluate its actual commercial potential iv) enter in contact with companies devoted to microscope engineering and development, and with detector manufacturers, to raise their interest, and envision under which form this new technology can be commercialized, how to conceive the corresponding commercial prototype.

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The information about "SUPER-RESOL" are provided by the European Opendata Portal: CORDIS opendata.

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