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R2R Biofluidics SIGNED

Large scale micro-and nanofabrication technologies for bioanalytical devices based on R2R imprinting

Total Cost €

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EC-Contrib. €

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Partnership

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 R2R Biofluidics project word cloud

Explore the words cloud of the R2R Biofluidics project. It provides you a very rough idea of what is the project "R2R Biofluidics" about.

industry    capacity    adopting    reduce    device    r2r    respect    assays    biofunctionalized    time    benefit    consist    printing    imprinted    plate    optical    flexible    fabrication    formats    neuron    ivd    care    first    notably    diagnostic    nanoimprinting    prices    standard    optics    micro    neurons    quantities    roll    volume    realization    graphical    vitro    structures    microfluidic    surfaces    fabricated    productivity    suitable    lab    microfluidics    combination    interconnected    techniques    roller    drug    nanostructures    demonstrators    technologies    microstructured    nanoscale    slides    nano    lines    unrivalled    complementary    screening    throughput    core    combined    patterns    electronics    manufacturing    microtiter    diagnostics    lower    mature    showing    point    demonstrator    sensitivity    chip    microscope    biofluidics    thanks    complete    types    precise    bioanalytical    discovery    chain    commercial    alignment    channels    food   

Project "R2R Biofluidics" data sheet

The following table provides information about the project.

Coordinator
JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH 

Organization address
address: LEONHARDSTRASSE 59
city: GRAZ
postcode: 8010
website: www.joanneum.at

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Austria [AT]
 Project website http://www.r2r-biofluidics.eu
 Total cost 7˙677˙557 €
 EC max contribution 6˙421˙672 € (84%)
 Programme 1. H2020-EU.2.1.2.1. (Developing next generation nanomaterials, nanodevices and nanosystems)
 Code Call H2020-NMP-PILOTS-2014
 Funding Scheme IA
 Starting year 2015
 Duration (year-month-day) from 2015-02-01   to  2019-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH AT (GRAZ) coordinator 2˙395˙932.00
2    FUNDACION TECNALIA RESEARCH & INNOVATION ES (DERIO BIZKAIA) participant 675˙563.00
3    INMOLD AS DK (HORSHOLM) participant 648˙579.00
4    MICRO RESIST TECHNOLOGY GESELLSCHAFT FUER CHEMISCHE MATERIALIEN SPEZIELLER PHOTORESISTSYSTEME MBH DE (BERLIN) participant 557˙375.00
5    BIONANONET FORSCHUNGSGESELLSCHAFT MBH AT (GRAZ) participant 419˙779.00
6    EV GROUP E. THALLNER GMBH AT (ST FLORIAN AM INN) participant 374˙268.00
7    GENSPEED BIOTECH GMBH AT (RAINBACH IM MUHLKREIS) participant 357˙897.00
8    Innovative Technologies in Biological Systems ES (Derio) participant 295˙515.00
9    BIFLOW SYSTEMS GMBH DE (CHEMNITZ) participant 247˙725.00
10    BIONIC SURFACE TECHNOLOGIES GMBH AT (GRAZ) participant 225˙050.00
11    SCIENION AG DE (DORTMUND) participant 197˙553.00
12    GREINER BIO-ONE DIAGNOSTICS GMBH AT (RAINBACH IM MUHLKREIS) participant 26˙434.00

Map

 Project objective

Roll-to-roll (R2R) technologies are mature core processes in manufacturing lines for graphical printing industry. In several other areas (e.g. electronics or optics) R2R techniques are emerging, being expected to notably lower the unit prices of flexible devices.

In particular, recently developed roller-based nanoimprinting methods enable unrivalled throughput and productivity for precise fabrication of micro- and nanoscale patterns. Areas that will benefit strongly from adopting such R2R nanoimprinting technologies are microfluidics and lab-on-chip products for diagnostics, drug discovery and food control. Such devices require combined printing of micro- and nanostructures and large quantities at low unit costs.

The project R2R Biofluidics aims on the development of a complete process chain for first-time realization of production lines for two selected bioanalytical lab-on-chip devices based on high-throughput R2R nanoimprinting in combination with complementary printing and manufacturing technologies.

Two types of demonstrators will be fabricated targeting application areas, which would clearly benefit from technology advancement in high volume manufacturing, show large potential for commercial exploitation and adopt current standard formats (microtiter plate and microscope slides).

Demonstrator 1 will represent an in-vitro diagnostic (IVD) chip suitable for point-of-care applications, showing improved sensitivity thanks to imprinted nanoscale optical structures and microfluidic channels. R2R fabrication will further greatly reduce production costs and increase manufacturing capacity with respect to currently used products.

Demonstrator 2 will provide a device for improved neuron based high-throughput screening assays in drug development. It will consist of nano– to microstructured, interconnected channels in combination with dedicated biofunctionalized surfaces for alignment and controlled growth of neurons.

 Deliverables

List of deliverables.
Fully functional DEM1 test-chips MRSA from batch based backend processing Demonstrators, pilots, prototypes 2020-04-06 08:39:07
Fully functional DEM2 test chips from batch based backend processes Demonstrators, pilots, prototypes 2020-04-06 08:39:07
Roll-to-roll pilot imprinting of DEM2 Demonstrators, pilots, prototypes 2020-04-06 08:39:07
Roll-to-roll pilot imprinting of DEM1 Demonstrators, pilots, prototypes 2020-04-06 08:39:07
DEM1 with R2R top & bottom foil with batch based backend processing Demonstrators, pilots, prototypes 2020-04-06 08:39:07
Safe-by-design report Documents, reports 2020-04-06 08:39:06
DEM1 chips with optical nano-struct. Demonstrators, pilots, prototypes 2020-04-06 08:39:06
DEM2 chips with radial design (Gen.2) Demonstrators, pilots, prototypes 2020-04-06 08:39:06
Roll-to-roll pilot manufacturing line Demonstrators, pilots, prototypes 2020-04-06 08:39:06
Public project website online Other 2020-04-06 08:39:06

Take a look to the deliverables list in detail:  detailed list of R2R Biofluidics deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 P. Toren, M. Rumpler, M. Smolka, A. Haase, S. Ruttloff, D. Nees, B. Stadlober, I. Katzmayr, B. Hierschlager, S. Kierstein, M. Sonnleitner, G. Bared, M. Horn, W. Weigel, J. Hesse
HIGH-THROUGHPUT ROLL-TO-ROLL PRODUCTION OF BIO-FUNCTIONALIZED POLYMER COMPONENTS
published pages: , ISSN: 2537-4346, DOI:
European Journal of Materials Science and Engineering 2020-04-06

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The information about "R2R BIOFLUIDICS" are provided by the European Opendata Portal: CORDIS opendata.

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