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PoC-Cycle

Innovative Molecular Diagnostics point-of-care device for MRSA

Total Cost €

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EC-Contrib. €

0

Partnership

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 PoC-Cycle project word cloud

Explore the words cloud of the PoC-Cycle project. It provides you a very rough idea of what is the project "PoC-Cycle" about.

diagnostics    routine    handling    pilot    appropriate    acceptance    spread    biomarkers    introducing    accuracy    experts    mrsa    innovative    format    fast    forecast    feasibility    complexity    version    few    prepares    million    turnover    approx    market    broad    almost    deaths    platform    discuss    significantly    health    workflow    pcr    semiconductor    rapid    2015    combination    limited    multiplexing    point    reduce    pathogen    detection    usability    device    collection    diagnose    efficient    variations    tuberculosis    revised    acid    missing    yearly    negative    mostly    diagnosis    microfluidic    care    multiplex    sensitive    screening    multicentric    disposable    pathogens    microarrays    patients    17    signatures    cartridge    interviewing    freedom    nucleic    cycle    optimized    provides    tests    hospitals    operate    diagnostic    sensitivity    sequence    robustness    friz    safe    administration    ing    area    hpv    poc    infections    checked    reg    technically    platforms    900    business    validation   

Project "PoC-Cycle" data sheet

The following table provides information about the project.

Coordinator
FRIZ BIOCHEM GMBH 

Organization address
address: FLORIANSBOGEN 2-4
city: NEURIED
postcode: 82061
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website http://www.frizbiochem.de
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-1-2014
 Funding Scheme SME-1
 Starting year 2014
 Duration (year-month-day) from 2014-09-01   to  2014-11-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FRIZ BIOCHEM GMBH DE (NEURIED) coordinator 50˙000.00

Map

 Project objective

FRIZ has developed PoC-Cycle® platform- an innovative diagnostics device introducing efficient multiplex nucleic acid testing to the point-of-care. It provides a combination of accuracy and sensitivity, multiplexing, and optimized workflow from sample collection to diagnosis. Current diagnostics platforms are technically limited: On one side only few sequence signatures can be checked, on the other side, the analysis of these signatures are mostly considered in one sequence area only due to the high complexity in developing Multiplex-PCR, as well as missing process-robustness for routine administration. FRIZ implemented a multiplex analysis in disposable microfluidic cartridge format with integrated semiconductor based on microarrays for the rapid and sensitive detection of a broad range and number of biomarkers. Key market is the screening of MRSA, a pathogen with wide spread and growing negative impact to European patients and health care systems. Experts forecast the number of deaths will increase from 6,000 to approx. 17,000 in 2015. Main users of the device are hospitals as they require simple and safe handling as well as fast and reliable results. European market potential can be estimated with 900,000 tests per year resulting in a yearly turnover of almost two million €. The new diagnostic device will significantly reduce the number of infections. Moreover, it provides future business opportunities due to its general approach for diagnose further pathogens e.g. HPV or tuberculosis. Within the project, FRIZ aims to identify end-users for validation, discuss the handling and identify possible variations to enhance the usability and acceptance of the new system in phase 2. To find an appropriate partner for validation is also part of this feasibility study. In addition, FRIZ prepares a revised version of a “freedom-to-operate” analysis. A multicentric validation study is planned as well as interviewing end-users and built up a pilot production in phase 2.

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The information about "POC-CYCLE" are provided by the European Opendata Portal: CORDIS opendata.

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