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PoC-Cycle

Innovative Molecular Diagnostics point-of-care device for MRSA

Total Cost €

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EC-Contrib. €

0

Partnership

0

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 PoC-Cycle project word cloud

Explore the words cloud of the PoC-Cycle project. It provides you a very rough idea of what is the project "PoC-Cycle" about.

robustness    appropriate    interviewing    900    nucleic    mrsa    pathogen    biomarkers    validation    discuss    17    revised    ing    few    tests    market    operate    multiplexing    limited    acceptance    innovative    approx    area    workflow    complexity    detection    missing    administration    feasibility    hospitals    deaths    health    accuracy    almost    disposable    business    collection    care    broad    efficient    pcr    million    technically    negative    safe    yearly    platforms    multiplex    diagnose    provides    reduce    introducing    usability    friz    pilot    rapid    handling    freedom    poc    2015    turnover    prepares    routine    semiconductor    microfluidic    variations    patients    point    format    platform    sensitivity    forecast    device    screening    diagnostic    cycle    pathogens    tuberculosis    multicentric    signatures    acid    version    hpv    mostly    diagnostics    significantly    sensitive    reg    optimized    sequence    combination    infections    diagnosis    microarrays    spread    checked    fast    cartridge    experts   

Project "PoC-Cycle" data sheet

The following table provides information about the project.

Coordinator
FRIZ BIOCHEM GMBH 

Organization address
address: FLORIANSBOGEN 2-4
city: NEURIED
postcode: 82061
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website http://www.frizbiochem.de
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-1-2014
 Funding Scheme SME-1
 Starting year 2014
 Duration (year-month-day) from 2014-09-01   to  2014-11-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FRIZ BIOCHEM GMBH DE (NEURIED) coordinator 50˙000.00

Map

 Project objective

FRIZ has developed PoC-Cycle® platform- an innovative diagnostics device introducing efficient multiplex nucleic acid testing to the point-of-care. It provides a combination of accuracy and sensitivity, multiplexing, and optimized workflow from sample collection to diagnosis. Current diagnostics platforms are technically limited: On one side only few sequence signatures can be checked, on the other side, the analysis of these signatures are mostly considered in one sequence area only due to the high complexity in developing Multiplex-PCR, as well as missing process-robustness for routine administration. FRIZ implemented a multiplex analysis in disposable microfluidic cartridge format with integrated semiconductor based on microarrays for the rapid and sensitive detection of a broad range and number of biomarkers. Key market is the screening of MRSA, a pathogen with wide spread and growing negative impact to European patients and health care systems. Experts forecast the number of deaths will increase from 6,000 to approx. 17,000 in 2015. Main users of the device are hospitals as they require simple and safe handling as well as fast and reliable results. European market potential can be estimated with 900,000 tests per year resulting in a yearly turnover of almost two million €. The new diagnostic device will significantly reduce the number of infections. Moreover, it provides future business opportunities due to its general approach for diagnose further pathogens e.g. HPV or tuberculosis. Within the project, FRIZ aims to identify end-users for validation, discuss the handling and identify possible variations to enhance the usability and acceptance of the new system in phase 2. To find an appropriate partner for validation is also part of this feasibility study. In addition, FRIZ prepares a revised version of a “freedom-to-operate” analysis. A multicentric validation study is planned as well as interviewing end-users and built up a pilot production in phase 2.

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The information about "POC-CYCLE" are provided by the European Opendata Portal: CORDIS opendata.

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