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PoC-Cycle

Innovative Molecular Diagnostics point-of-care device for MRSA

Total Cost €

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EC-Contrib. €

0

Partnership

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 Outcomes and results

 PoC-Cycle project word cloud

Explore the words cloud of the PoC-Cycle project. It provides you a very rough idea of what is the project "PoC-Cycle" about.

multiplexing    validation    acid    rapid    checked    disposable    handling    significantly    acceptance    sequence    hpv    discuss    deaths    microarrays    microfluidic    format    collection    tests    biomarkers    usability    diagnostics    interviewing    sensitivity    infections    efficient    turnover    nucleic    poc    17    introducing    few    forecast    pcr    spread    friz    variations    multicentric    broad    revised    workflow    fast    limited    experts    yearly    reduce    cycle    accuracy    reg    innovative    tuberculosis    mostly    routine    pathogen    combination    ing    900    device    prepares    safe    mrsa    diagnosis    platforms    health    care    robustness    platform    administration    freedom    point    appropriate    hospitals    negative    cartridge    million    multiplex    provides    screening    operate    detection    area    version    sensitive    business    pathogens    signatures    missing    diagnostic    market    complexity    semiconductor    almost    2015    patients    optimized    feasibility    pilot    technically    diagnose    approx   

Project "PoC-Cycle" data sheet

The following table provides information about the project.

Coordinator		 FRIZ BIOCHEM GMBH 

Organization address
address: FLORIANSBOGEN 2-4
city: NEURIED
postcode: 82061
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Germany [DE]
 Project website http://www.frizbiochem.de
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-1-2014
 Funding Scheme SME-1
 Starting year 2014
 Duration (year-month-day) from 2014-09-01   to  2014-11-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FRIZ BIOCHEM GMBH DE (NEURIED) coordinator 50˙000.00

Map

 Project objective

FRIZ has developed PoC-Cycle® platform- an innovative diagnostics device introducing efficient multiplex nucleic acid testing to the point-of-care. It provides a combination of accuracy and sensitivity, multiplexing, and optimized workflow from sample collection to diagnosis. Current diagnostics platforms are technically limited: On one side only few sequence signatures can be checked, on the other side, the analysis of these signatures are mostly considered in one sequence area only due to the high complexity in developing Multiplex-PCR, as well as missing process-robustness for routine administration. FRIZ implemented a multiplex analysis in disposable microfluidic cartridge format with integrated semiconductor based on microarrays for the rapid and sensitive detection of a broad range and number of biomarkers. Key market is the screening of MRSA, a pathogen with wide spread and growing negative impact to European patients and health care systems. Experts forecast the number of deaths will increase from 6,000 to approx. 17,000 in 2015. Main users of the device are hospitals as they require simple and safe handling as well as fast and reliable results. European market potential can be estimated with 900,000 tests per year resulting in a yearly turnover of almost two million €. The new diagnostic device will significantly reduce the number of infections. Moreover, it provides future business opportunities due to its general approach for diagnose further pathogens e.g. HPV or tuberculosis. Within the project, FRIZ aims to identify end-users for validation, discuss the handling and identify possible variations to enhance the usability and acceptance of the new system in phase 2. To find an appropriate partner for validation is also part of this feasibility study. In addition, FRIZ prepares a revised version of a “freedom-to-operate” analysis. A multicentric validation study is planned as well as interviewing end-users and built up a pilot production in phase 2.

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The information about "POC-CYCLE" are provided by the European Opendata Portal: CORDIS opendata.

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