Opendata, web and dolomites
  1. home
  2. trasparenza
  3. open h2020
  4. stemcelltrack

STEMCELLTRACK

Assessment of Global and Regional Cardiac Functional Improvements in a Murine Model of Myocardial Infarction following Stem Cell Treatments

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0
 Outcomes and results

 STEMCELLTRACK project word cloud

Explore the words cloud of the STEMCELLTRACK project. It provides you a very rough idea of what is the project "STEMCELLTRACK" about.

labeling    researcher    evaluation    functional    infarction    retention    parallel    engineering    myocardial    engraftment    magnetic    stem    enriched    fiber    personalized    labeled    chair    cutting    technologies    cellular    synthesis    cdcs    vivo    cell    broadening    homing    injection    applicability    mi    sc    cardiosphere    tools    viability    investigator    tracking    cdc    cardiac    stimulated    plan    leadership    quantification    efficacy    trans    elicit    moderate    19    scaffolds    microinjection    heart    invasive    mobility    scientific    shown    advancing    manufacturing    characterization    regenerative    bio    edge    beneficial    independent    efforts    reinforcing    imaging    techniques    validation    scaffold    synergistically    career    regional    global    qualities    therapy    disease    anticipated    managerial    fluorine    multifaceted    prominent    horizons    function    training    cardiomyopathies    mri    resonance    biomedical    science    administration    post    fellowship    scs   

Project "STEMCELLTRACK" data sheet

The following table provides information about the project.

Coordinator		 THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD 

Organization address
address: WELLINGTON SQUARE UNIVERSITY OFFICES
city: OXFORD
postcode: OX1 2JD
website: www.ox.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country United Kingdom [UK]
 Project website http://lbi-cy.com/
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-07-01   to  2017-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD UK (OXFORD) coordinator 183˙454.00

Map

 Project objective

Cardiosphere-derived stem cell (CDC) therapy for myocardial infarction (MI) has been shown to elicit moderate beneficial effects. Research currently focuses on improving CDC administration, retention and efficacy. This proposal aims to develop Magnetic Resonance Imaging (MRI) and engineering tools to facilitate this research. Specifically, microinjection of fluorine-19 labeled CDCs will allow for MRI tracking and quantification in vivo. Non-invasive global and regional cardiac function measurements will assess efficacy of stem cell (SC) therapy. Parallel to these studies will be an independent design, synthesis, use and evaluation of fiber-enriched scaffold. The anticipated impact will be multifaceted, including the study of cardiac function in disease, and the potential applicability of generated results with cutting edge SC regenerative technologies in heart failure and prominent cardiomyopathies. Research efforts will be stimulated in manufacturing processes for scaffolds, cardiac functional assessment post-injection of SCs, and validation of their homing, engraftment and viability using cellular tracking methods. Through a personalized career developments plan, the fellowship will allow training of the researcher in advanced cellular characterization, labeling, and bio-imaging techniques, synergistically with trans-European mobility, reinforcing his scientific, managerial and leadership qualities. Overall, the short-term objective is the advancement of the researcher’s career in science and the broadening of his scientific horizons. The long-term objective is to establish the researcher as an independent investigator, advancing the field as a chair of a Biomedical Engineering Department.

 Publications

year authors and title journal last update
List of publications.
2016 Christakis Constantinides, Mahon L. Maguire, Sophia Malandraki-Miller, Edyta Swider, Mangala Srinivas, Carolyn A. Carr, Jurgen E. Schneider.
Fast, Quantitative 19F MRI: Optimized Imaging Strategies.
published pages: , ISSN: , DOI: 		ESMRMB 2016 2019-06-07
2016 Christakis Constantinides, Eileen McNeill, Matt Benson, Raquel Sainz Urruela, Sergi Padilla, Sophia Malandraki-Miller, Mahon L. Maguire, Edyta Swider, Sahar Ghaffari, Carolyn A. Carr, Mangala Srinivas, Jurgen E. Schneider.
Improvements in the Cellular Uptake of Perfluorocarbon Nanoparticles and 19F MRS/MRI Detectability using the Transfection Agent FuGENE.
published pages: , ISSN: , DOI: 		ISMRM Workshop on Molecular and Cellular MRI: Focus on Integration: Amsterdam, Netherlands, June 2016. 2019-06-07
2018 Christakis Constantinides, Mahon Maguire, Eileen McNeill, Ricardo Carnicer, Edyta Swider, Mangala Srinivas, Carolyn A. Carr, Jurgen E. Schneider
Fast, quantitative, murine cardiac 19F MRI/MRS of PFCE-labeled progenitor stem cells and macrophages at 9.4T
published pages: e0190558, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0190558 		PLOS ONE 13/1 2019-06-07
2016 C. Constantinides
Cardiac Image-Based Phenotyping: A Scientific Fairytale or an Emerging Reality?
published pages: 18-19, ISSN: , DOI: 		Phenotype Issue 24 2019-06-07
2017 Christakis Constantinides, Mahon L. Maguire, Leeanne Stork, Edyta Swider, Mangala Srinivas, Carolyn A. Carr, Jurgen E. Schneider
Temporal accumulation and localization of isoflurane in the C57BL/6 mouse and assessment of its potential contamination in 19 F MRI with perfluoro-crown-ether-labeled cardiac progenitor cells at 9.4 Tesla
published pages: 1659-1667, ISSN: 1053-1807, DOI: 10.1002/jmri.25564 		Journal of Magnetic Resonance Imaging 45/6 2019-06-07
2016 Christakis Constantinides, Mahon L. Maguire, Leeanne Stork, Mangala Srinivas, Edyta Swider, Carolyn A. Carr, Jurgen E. Schneider.
Effects of Inhalational Isoflurane Anaesthesia on 19F MRS/MRI of the In Vivo Mouse at 9.4T.
published pages: , ISSN: , DOI: 		ISMRM Workshop on Molecular and Cellular MRI: Focus on Integration: Amsterdam, Netherlands, June 2016. 2019-06-07
2016 Christakis Constantinides, Kathy Murphy
Molecular and Integrative Physiological Effects of Isoflurane Anesthesia: The Paradigm of Cardiovascular Studies in Rodents using Magnetic Resonance Imaging
published pages: 1-15, ISSN: 2297-055X, DOI: 10.3389/fcvm.2016.00023 		Frontiers in Cardiovascular Medicine 3 2019-06-07

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "STEMCELLTRACK" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "STEMCELLTRACK" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

EVOMET (2019)

The rise and fall of metastatic clones under immune attack

Read More  

ICARUS (2020)

Information Content of locAlisation: fRom classical to qUantum Systems

Read More  

ReSOLeS (2019)

New Reconfigurable Spectrum Optical Fibre Laser Sources

Read More