Explore the words cloud of the RESCUE THE HEART project. It provides you a very rough idea of what is the project "RESCUE THE HEART" about.
The following table provides information about the project.
UNIVERSITY COLLEGE LONDON
|Coordinator Country||United Kingdom [UK]|
|Total cost||195˙454 €|
|EC max contribution||195˙454 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2016-04-01 to 2018-03-31|
Take a look of project's partnership.
|1||UNIVERSITY COLLEGE LONDON||UK (LONDON)||coordinator||195˙454.00|
This project is designed to use the latest advances in molecular biology and neuroscience to determine the role played by the nervous mechanisms in the development of cardiovascular pathology. The project spans across distinct research fields of myocardial ischaemia/reperfusion injury, innate cardioprotective mechanisms and fundamental neuroscience and includes newly developed transgenic mice models and latest advances in viral gene transfer technology, pharmaco- and optogenetics for selective manipulation of parasympathetic or sympathetic efferent outflows to the heart. These novel genetic models offer unprecedented resolution and specificity and will be used to determine the role played by the autonomic nervous system in modulation of the myocardial ischaemia/reperfusion injury and progression of chronic heart failure. Another important part of this study will determine the involvement of neural pathways in powerful innate mechanisms of cardioprotection underlying the (pre)conditioning phenomena. The results of the proposed experiments are expected to have an instant translational potential and may lead to the development of novel therapeutic strategies which recruit innate neural mechanisms of cardioprotection to limit myocardial injury and improve quality of life of individuals suffering from heart disease. RESCUE THE HEART project includes an intense program of research and training to be undertaken by the experienced researcher and will ultimately promote effective transfer of research expertise, new technologies and research philosophy across wider European research base.
|year||authors and title||journal||last update|
Fergus M O\'Farrell, Svetlana Mastitskaya, Matthew Hammond-Haley, Felipe Freitas, Wen Rui Wah, David Attwell
Capillary pericytes mediate coronary no-reflow after myocardial ischaemia
published pages: , ISSN: 2050-084X, DOI: 10.7554/eLife.29280
Svetlana Mastitskaya, Marina Basalay, Patrick S. Hosford, Andrew G. Ramage, Andrey Gourine, Alexander V. Gourine
Identifying the Source of a Humoral Factor of Remote (Pre)Conditioning Cardioprotection
published pages: e0150108, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0150108
|PLOS ONE 11/2||2019-06-13|
Marina V. Basalay, Svetlana Mastitskaya, Aleksander Mrochek, Gareth L. Ackland, Ana Gutierrez del Arroyo, Jenifer Sanchez, Per-Ove Sjoquist, John Pernow, Alexander V. Gourine, Andrey Gourine
Glucagon-like peptide-1 (GLP-1) mediates cardioprotection by remote ischaemic conditioning
published pages: 669-676, ISSN: 0008-6363, DOI: 10.1093/cvr/cvw216
|Cardiovascular Research 112/3||2019-06-13|
Marina Basalay, Svetlana Mastitskaya, Aleksander Mrochek, Gareth L. Ackland, Ana Gutierrez del Arroyo, Jenifer Sanchez, Per-Ove Sjoquist, John Pernow, Alexander V. Gourine, Andrey Gourine
Reply: Glucagon-like peptide-1 mediates cardioprotection by remote ischaemic conditioning
published pages: 13.2-14, ISSN: 0008-6363, DOI: 10.1093/cvr/cvw238
|Cardiovascular Research 113/1||2019-06-13|
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The information about "RESCUE THE HEART" are provided by the European Opendata Portal: CORDIS opendata.
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