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Cell-surface immobilized vs. internalized magnetic nanoparticles for magnetic hyperthermia studies

Total Cost €


EC-Contrib. €






 OUTstandINg project word cloud

Explore the words cloud of the OUTstandINg project. It provides you a very rough idea of what is the project "OUTstandINg" about.

nanotherapy    complete    supervisor    attach    msc    university    immobilization    gn2    prof    magnetic    fuente    london    fellow    surfaces    nanotechnology    outstanding    bioorthogonal    therapy    questions    spain    acquire    biology    tool    host    multidisciplinary    quentin    raluca    group    career    excellence    training    localization    inside    skills    period    living    college    era    action    collaborations    iacute    fratila    zaragoza    solution    hyperthermia    science    mnps    lethal    chemistry    nanoscience    cell    nez    nanomedicine    position    she    jes    biophysics    edge    cells    subcellular    de    dr    scientific    nanobiosensors    generate    nanoparticles    membranes    heating    plasma    covalently    frontier    nano    membrane    progress    reinforce    sub    physics    fundamental    mart    uacute    independent    bioconjugates    click    secondment    expertise    engineering    biomedical    materials    area    possibility    signalling    cutting    pankhurst    la    bioorganic    functionalization   

Project "OUTstandINg" data sheet

The following table provides information about the project.


Organization address
postcode: 50009

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website
 Total cost 158˙121 €
 EC max contribution 158˙121 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-09-01   to  2017-08-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSIDAD DE ZARAGOZA ES (ZARAGOZA) coordinator 158˙121.00


 Project objective

The MSC OUTstandINg project will use bioorthogonal click chemistry as tool to covalently attach magnetic nanoparticles (MNPs) to living cell surfaces with the aim to address two fundamental questions in the field of magnetic hyperthermia therapy using MNPs: 1) how the subcellular localization (on the plasma membrane or inside the cells) of MNPs affects their heating behaviour when compared to MNPs in solution 2) how MNPs immobilization and sub-lethal magnetic hyperthermia impact different subcellular signalling pathways and the biophysics of cell membranes. OUTstandINg is a multidisciplinary two-years research project built upon the expertise of the Fellow (Dr. Raluca M. Fratila) in bioorganic chemistry (including click chemistry, bioconjugates and functionalization of surfaces and (nano)materials) and the experience of the supervisor (Dr. Jesús Martínez de la Fuente) and of the host group (GN2 - Nanotherapy and Nanobiosensors, University of Zaragoza, Spain) in nanotechnology and nanomedicine. This MSC action will offer the Fellow the possibility to work in one of the top European institutions in nanoscience, where she will further develop her skills and will acquire new skills and knowledge necessary for the progress of her scientific career towards an independent position. The secondment period at University College London Institute for Biomedical Engineering (supervisor Prof. Quentin Pankhurst) will reinforce and complete the multidisciplinary training-through-research. The project will generate important knowledge and collaborations in the European Research Area (ERA) and will contribute to enhance the excellence of ERA through cutting-edge research at the frontier of chemistry, physics, materials science, cell biology and nanotechnology.


year authors and title journal last update
List of publications.
2017 Raluca M. Fratila, Marcos Navascuez, Javier Idiago-López, Maite Eceiza, José I. Miranda, Jesús M. Aizpurua, Jesús M. de la Fuente
Covalent immobilisation of magnetic nanoparticles on surfaces via strain-promoted azide–alkyne click chemistry
published pages: , ISSN: 1144-0546, DOI: 10.1039/c7nj01822c
New J. Chem. 2019-07-23

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The information about "OUTSTANDING" are provided by the European Opendata Portal: CORDIS opendata.

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