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OUTstandINg

Cell-surface immobilized vs. internalized magnetic nanoparticles for magnetic hyperthermia studies

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 OUTstandINg project word cloud

Explore the words cloud of the OUTstandINg project. It provides you a very rough idea of what is the project "OUTstandINg" about.

nanotherapy    multidisciplinary    university    dr    gn2    tool    scientific    therapy    generate    engineering    prof    plasma    click    science    skills    fuente    expertise    position    uacute    frontier    raluca    quentin    biomedical    subcellular    supervisor    possibility    signalling    nanoparticles    mart    de    acquire    fellow    cutting    outstanding    inside    lethal    nanotechnology    nanoscience    spain    membrane    attach    independent    group    area    action    she    hyperthermia    heating    localization    covalently    jes    college    london    membranes    la    cells    surfaces    excellence    bioorthogonal    magnetic    nez    physics    nanomedicine    immobilization    fundamental    secondment    questions    cell    mnps    training    period    biology    biophysics    bioorganic    chemistry    bioconjugates    host    iacute    functionalization    edge    msc    fratila    era    collaborations    solution    career    nanobiosensors    progress    complete    nano    sub    zaragoza    materials    reinforce    pankhurst    living   

Project "OUTstandINg" data sheet

The following table provides information about the project.

Coordinator
UNIVERSIDAD DE ZARAGOZA 

Organization address
address: CALLE PEDRO CERBUNA 12
city: ZARAGOZA
postcode: 50009
website: www.unizar.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website http://bionanosurf.unizar.es
 Total cost 158˙121 €
 EC max contribution 158˙121 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-09-01   to  2017-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSIDAD DE ZARAGOZA ES (ZARAGOZA) coordinator 158˙121.00

Map

 Project objective

The MSC OUTstandINg project will use bioorthogonal click chemistry as tool to covalently attach magnetic nanoparticles (MNPs) to living cell surfaces with the aim to address two fundamental questions in the field of magnetic hyperthermia therapy using MNPs: 1) how the subcellular localization (on the plasma membrane or inside the cells) of MNPs affects their heating behaviour when compared to MNPs in solution 2) how MNPs immobilization and sub-lethal magnetic hyperthermia impact different subcellular signalling pathways and the biophysics of cell membranes. OUTstandINg is a multidisciplinary two-years research project built upon the expertise of the Fellow (Dr. Raluca M. Fratila) in bioorganic chemistry (including click chemistry, bioconjugates and functionalization of surfaces and (nano)materials) and the experience of the supervisor (Dr. Jesús Martínez de la Fuente) and of the host group (GN2 - Nanotherapy and Nanobiosensors, University of Zaragoza, Spain) in nanotechnology and nanomedicine. This MSC action will offer the Fellow the possibility to work in one of the top European institutions in nanoscience, where she will further develop her skills and will acquire new skills and knowledge necessary for the progress of her scientific career towards an independent position. The secondment period at University College London Institute for Biomedical Engineering (supervisor Prof. Quentin Pankhurst) will reinforce and complete the multidisciplinary training-through-research. The project will generate important knowledge and collaborations in the European Research Area (ERA) and will contribute to enhance the excellence of ERA through cutting-edge research at the frontier of chemistry, physics, materials science, cell biology and nanotechnology.

 Publications

year authors and title journal last update
List of publications.
2017 Raluca M. Fratila, Marcos Navascuez, Javier Idiago-López, Maite Eceiza, José I. Miranda, Jesús M. Aizpurua, Jesús M. de la Fuente
Covalent immobilisation of magnetic nanoparticles on surfaces via strain-promoted azide–alkyne click chemistry
published pages: , ISSN: 1144-0546, DOI: 10.1039/c7nj01822c
New J. Chem. 2019-07-23

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The information about "OUTSTANDING" are provided by the European Opendata Portal: CORDIS opendata.

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