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[e-POM-Bioanal] SIGNED

Electrobioanalytical Applications of Polyoxometalates

Total Cost €

0

EC-Contrib. €

0

Partnership

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Project "[e-POM-Bioanal]" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 

There are not information about this coordinator. Please contact Fabio for more information, thanks.

 Coordinator Country France [FR]
 Project website http://www.ipcm.fr
 Total cost 185˙076 €
 EC max contribution 185˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-06-01   to  2017-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    SORBONNE UNIVERSITE FR (PARIS) coordinator 185˙076.00
2    UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 FR (PARIS) coordinator 0.00

Map

 Project objective

The proposed work will exploit the expertise and know-how of the host institute and the fellow to develop a strategy for the detection and screening of genetic mutations in a highly parallelised fashion.The project has an overall objective to develop an electrochemical single nucleotide polymorphism (SNP) detection strategy by using polyoxometalate (POM) labeled DNA (including PCR primers, dNTPs and ddNTPs) for use in solid-phase melting curve analysis and sold-phase array based primer extension and solid phase ligase mediated detection. In order to achieve this, robust surface for anchoring of DNA probes capable of withstanding elevated temperature for enzymatic reactions either in solid phase melting curve analysis or single dideoxynucleotide incorporation will be developed. The proposed strategies will allow for highly cost-effective, rapid and user-friendly platforms for the screening of genetic mutations and single nucleotide polymorphisms.

 Publications

year authors and title journal last update
List of publications.
2015 Ahmed M. Debela, Mayreli Ortiz, Valerio Beni, Serge Thorimbert, Denis Lesage, Richard B. Cole, Ciara K. O\'Sullivan, Bernold Hasenknopf
Biofunctionalization of Polyoxometalates with DNA Primers, Their Use in the Polymerase Chain Reaction (PCR) and Electrochemical Detection of PCR Products
published pages: 17721-17727, ISSN: 0947-6539, DOI: 10.1002/chem.201502247
Chemistry - A European Journal 21/49 2019-06-17
2016 A. M. Debela, S. Thorimbert, B. Hasenknopf, C. K. O\'Sullivan, M. Ortiz
Electrochemical primer extension for the detection of single nucleotide polymorphisms in the cardiomyopathy associated MYH7 gene
published pages: 757-759, ISSN: 1359-7345, DOI: 10.1039/C5CC07762A
Chem. Commun. 52/4 2019-06-17
2017 Ciara K O\'Sullivan, Mayreli Ortiz, Ahmed Debela Mehdi, Marketa Svobodova, Serge Thorimbert, Denis Lasage, Richard Cole, Bernold Hasenknopf
PCR Incorporation of Polyoxometalate Modified Deoxynucleotide Triphosphates and Their Application in Molecular Electrochemical Sensing of Yersinia pestis
published pages: , ISSN: 0947-6539, DOI: 10.1002/chem.201701295
Chemistry - A European Journal 2019-06-17

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The information about "[E-POM-BIOANAL]" are provided by the European Opendata Portal: CORDIS opendata.

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