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CHIRALSENSE

CHIRALSENSE : Sensing Chirality using cavity-enhanced polarimetry: advances in sensitivity and time-resolution

Total Cost €

0

EC-Contrib. €

0

Partnership

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 CHIRALSENSE project word cloud

Explore the words cloud of the CHIRALSENSE project. It provides you a very rough idea of what is the project "CHIRALSENSE" about.

small    polarimetric    commercial    multibillion    chromatography    patent    quality    absolute    detection    industries    optical    liquid    circular    ipr    signal    time    passes    sensitivity    al    standard    provisional    sofikitis    suppressed    adapt    protein    et    demonstrated    erc    stages    analytical    size    enhanced    resolution    food    samples    backgrounds    pharmaceutical    hplc    polarimeter    industry    removed    orders    signals    filing    1000    ranging    respect    rotation    techniques    separated    chiral    protection    file    cosmetic    sizes    first    performing    514    acquisition    null    chiralsense    advantages    improvements    birefringent    companies    cavity    commercially    performance    groundbreaking    76    dichroism    requiring    chemical    triceps    sensing    cd    nature    constituting    polarimetry    chemistry    grant    reversals    reduce    structure    place    constraints    give    polarimeters    2014    magnitude    follow    severe   

Project "CHIRALSENSE" data sheet

The following table provides information about the project.

Coordinator
IDRYMA TECHNOLOGIAS KAI EREVNAS 

Organization address
address: N PLASTIRA STR 100
city: IRAKLEIO
postcode: 70013
website: www.forth.gr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Greece [EL]
 Total cost 150˙000 €
 EC max contribution 150˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-PoC
 Funding Scheme ERC-POC
 Starting year 2015
 Duration (year-month-day) from 2015-04-01   to  2016-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    IDRYMA TECHNOLOGIAS KAI EREVNAS EL (IRAKLEIO) coordinator 150˙000.00

Map

 Project objective

Chiral sensing is crucial to many fields, constituting a multibillion Euro industry. The polarimetric techniques of optical rotation (OR) and circular dichroism (CD) are the most widely-used techniques for the analysis of chiral samples, ranging from the measurement of protein structure, to quality control in the pharmaceutical, chemical, cosmetic, and food industries. In general, the OR and CD signals are very small, which place severe constraints on detection sensitivity and time-resolution. Through the ERC grant TRICEPS, we have developed a groundbreaking cavity-based polarimeter [Sofikitis et al. Nature 514, 76 (2014)] with 3 main advantages: (a) The OR and CD signals are enhanced by the number of cavity passes (typically 1000); (b) birefringent backgrounds are suppressed; (c) signal reversals give absolute polarimetry measurements, not requiring the sample to be removed to measure a null sample. These advantages represent orders-of-magnitude improvements in sensitivity, acquisition time, and sample size, with respect to commercially available polarimeters, and will reduce measurement time, sample sizes, and costs in the chiral sensing industry. We propose, through CHIRALSENSE, to: (1) file a non-provisional US patent application, to follow our filing of a US provisional patent application for our polarimeter, which will provide IPR protection for the first stages of the product development; (2) demonstrate our existing CHIRALSENSE polarimeter to leading polarimetry companies, by performing measurements on commercial-standard samples; and (3) adapt our polarimeter to measure complex samples separated using HPLC (high-performance liquid chromatography) for analytical chemistry applications, to be demonstrated to leading HPLC companies.

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The information about "CHIRALSENSE" are provided by the European Opendata Portal: CORDIS opendata.

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