Opendata, web and dolomites

ProPlantStress SIGNED

Proteolytic processing in plant stress signal transduction and responses to abiotic stress and pathogen attack

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 ProPlantStress project word cloud

Explore the words cloud of the ProPlantStress project. It provides you a very rough idea of what is the project "ProPlantStress" about.

employ    proplantstress    regulates    transduction    recognition    strategies    resolved    modification    chloroplast    proteins    despite    serendipitously    modifications    crop    encoded    acclimation    reveal    function    combined    genomes    abiotic    domains    processed    effector    host    mitigation    post    intensity    metabolic    insights    subcellular    hypotheses    light    sites    biotic    protection    phosphorylation    substrates    fundamental    rarely    quantitative    implicated    species    substrate    proteolytic    repertoires    site    systemic    identification    mapping    merely    protein    locations    arabidopsis    bacterial    triggered    gt    correlation    cleavage    profiling    stress    retrograde    testable    mechanisms    co    time    functions    harvest    signal    catalogue    immune    translational    postdoctoral    800    hormonal    interactions    examined    pathogen    thereby    termini    irreversible    protease    underlying    plant    proteases    hundreds    plants    unattainable    largely    signaling    proteomics    few    linked    generates    positional   

Project "ProPlantStress" data sheet

The following table provides information about the project.

Coordinator
FORSCHUNGSZENTRUM JULICH GMBH 

Organization address
address: WILHELM JOHNEN STRASSE
city: JULICH
postcode: 52428
website: www.fz-juelich.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website http://www.proteasedegradomics.org/plant-degradomics.html
 Total cost 1˙804˙663 €
 EC max contribution 1˙804˙663 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-STG
 Funding Scheme ERC-STG
 Starting year 2015
 Duration (year-month-day) from 2015-06-01   to  2020-11-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FORSCHUNGSZENTRUM JULICH GMBH DE (JULICH) coordinator 1˙804˙663.00

Map

 Project objective

Site-specific proteolytic processing is an irreversible post-translational protein modification that generates distinct protein species with new functions, interactions and subcellular locations. In plants, proteolytic processing regulates hormonal and stress signaling leading to adaptation of metabolic pathways and is implicated in plant-pathogen interactions. Despite their importance, proteolytic processes have largely been identified serendipitously, specific cleavage sites have rarely been identified and only a few of the hundreds of proteases encoded in plant genomes (>800 in Arabidopsis) have been linked to any substrates. Positional proteomics enables system-wide identification of proteolytic processing and protease substrate repertoires through quantitative determination of protein N- or C-termini. ProPlantStress will employ these approaches, which I co-developed during my postdoctoral research, to two linked abiotic and biotic stress conditions: i) Time-resolved mapping of chloroplast protein processing induced by high intensity light will reveal novel mechanisms of retrograde signal transduction, stress response and acclimation; ii) Profiling of protein processing triggered by pathogen recognition, combined with substrate identification for selected host and bacterial pathogen effector proteases will identify proteins with novel functions in plant immune responses and systemic signaling. Importantly, ProPlantStress will not merely catalogue termini and substrates: Mapping of cleavage sites to the protein domains and correlation with other modifications, such as phosphorylation, generates testable hypotheses on the function of processed protein species that will be examined in detail. ProPlantStress will thereby provide fundamental insights into proteolytic mechanisms underlying plant stress responses that are unattainable by other means. In the long term such knowledge is needed to develop new strategies for crop protection and mitigation of harvest loss.

 Publications

year authors and title journal last update
List of publications.
2020 Wai Tuck Soh, Fatih Demir, Elfriede Dall, Andreas Perrar, Sven O. Dahms, Maithreyan Kuppusamy, Hans Brandstetter, Pitter F. Huesgen
ExteNDing Proteome Coverage with Legumain as a Highly Specific Digestion Protease
published pages: 2961-2971, ISSN: 0003-2700, DOI: 10.1021/acs.analchem.9b03604
Analytical Chemistry 92/4 2020-03-23
2020 Stefan Niedermaier, Trang Schneider, Marc-Oliver Bahl, Shizue Matsubara, Pitter F. Huesgen
Photoprotective Acclimation of the Arabidopsis thaliana Leaf Proteome to Fluctuating Light
published pages: , ISSN: 1664-8021, DOI: 10.3389/fgene.2020.00154
Frontiers in Genetics 11 2020-03-23
2019 Samuel SH Weng, Fatih Demir, Enes K. Ergin, Sabrina Dirnberger, Anuli Uzozie, Domenic Tuscher, Lorenz Nierves, Janice Tsui, Pitter F. Huesgen, Philipp F. Lange
Sensitive determination of proteolytic proteoforms in limited microscale proteome samples
published pages: mcp.TIR119.00156, ISSN: 1535-9476, DOI: 10.1074/mcp.TIR119.001560
Molecular & Cellular Proteomics 2020-01-24
2019 Catharina V Huber, Barbara D Jakobs, Laxmi S Mishra, Stefan Niedermaier, Marc Stift, Gudrun Winter, Iwona Adamska, Christiane Funk, Pitter F Huesgen, Dietmar Funck
DEG10 contributes to mitochondrial proteostasis, root growth, and seed yield in Arabidopsis
published pages: , ISSN: 0022-0957, DOI: 10.1093/jxb/erz294
Journal of Experimental Botany 2020-01-24
2017 Markus M. Rinschen, Ann-Kathrin Hoppe, Florian Grahammer, Martin Kann, Linus A. Völker, Eva-Maria Schurek, Julie Binz, Martin Höhne, Fatih Demir, Milena Malisic, Tobias B. Huber, Christine Kurschat, Jayachandran N. Kizhakkedathu, Bernhard Schermer, Pitter F. Huesgen, Thomas Benzing
N-Degradomic Analysis Reveals a Proteolytic Network Processing the Podocyte Cytoskeleton
published pages: 2867-2878, ISSN: 1046-6673, DOI: 10.1681/ASN.2016101119
Journal of the American Society of Nephrology 28/10 2020-01-24
2019 Johana C. Misas Villamil, André N. Mueller, Fatih Demir, Ute Meyer, Bilal Ökmen, Jan Schulze Hüynck, Marlen Breuer, Helen Dauben, Joe Win, Pitter F. Huesgen, Gunther Doehlemann
A fungal substrate mimicking molecule suppresses plant immunity via an inter-kingdom conserved motif
published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-019-09472-8
Nature Communications 10/1 2020-01-24
2018 Fatih Demir, Stefan Niedermaier, Joji Grace Villamor, Pitter Florian Huesgen
Quantitative proteomics in plant protease substrate identification
published pages: 936-943, ISSN: 0028-646X, DOI: 10.1111/nph.14587
New Phytologist 218/3 2020-01-24
2019 Andreas Perrar, Nico Dissmeyer, Pitter F Huesgen
New beginnings and new ends – Methods for large-scale characterization of protein termini and their use in plant biology
published pages: , ISSN: 0022-0957, DOI: 10.1093/jxb/erz104
Journal of Experimental Botany 2020-01-24
2019 Fatih Demir, Andreas Perrar, Pitter F. Huesgen
Das maßgeschneiderte Proteom: Proteinmodifikation durch Proteolyse
published pages: 41-44, ISSN: 0947-0867, DOI: 10.1007/s12268-019-1003-4
BIOspektrum 25/1 2020-01-24
2018 Stefan Niedermaier, Pitter F. Huesgen
Positional proteomics for identification of secreted proteoforms released by site-specific processing of membrane proteins
published pages: , ISSN: 1570-9639, DOI: 10.1016/j.bbapap.2018.09.004
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 2020-01-24

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "PROPLANTSTRESS" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "PROPLANTSTRESS" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

WEB DATA OPP (2020)

New opportunities to enhance or extend (mobile) web survey data and get better insights

Read More  

HMS (2020)

Homological mirror symmetry, Hodge theory, and symplectic topology

Read More  

CANCEREVO (2019)

Deciphering and predicting the evolution of cancer cell populations

Read More