Opendata, web and dolomites

PhageDiff SIGNED

Distinct Infection Dynamics and Ecological Success among Closely Related Marine Cyanophages: Why the Differences?

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

Project "PhageDiff" data sheet

The following table provides information about the project.

Coordinator
TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY 

Organization address
address: SENATE BUILDING TECHNION CITY
city: HAIFA
postcode: 32000
website: www.technion.ac.il

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Israel [IL]
 Total cost 2˙162˙296 €
 EC max contribution 2˙162˙296 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-CoG
 Funding Scheme ERC-COG
 Starting year 2015
 Duration (year-month-day) from 2015-09-01   to  2020-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY IL (HAIFA) coordinator 2˙162˙296.00

Map

 Project objective

Viruses are extremely abundant in the oceans and majorly impact the marine ecosystem by influencing the abundance, diversity and evolution of their hosts. However, our understanding of marine viral physiology and ecology among different members of the virus community is conspicuously lacking. Preliminary data using a newly developed molecular method revealed drastic differences in field abundances of two subtypes of T7-like podoviruses that infect marine cyanobacteria. Moreover, these subtypes displayed large differences in infection properties in laboratory studies. The main objective of this proposal is to gain a deep understanding of the genetic basis for the physiological differences in infection dynamics among closely related T7-like cyanophages that infect the globally important marine cyanobacteria, Synechococcus and Prochlorococcus, and to ascertain the ecological consequences of these physiological differences. We hypothesize that a small set of genes, beyond the core replication and morphogenesis genes, differentially impact the dynamics of the infection process which, in-turn, defines the niche occupied by discrete members of this virus family. Our specific objectives are to identify the genes responsible for the physiological differences and determine their impact on infection dynamics. This will be achieved through the development of a phage gene inactivation system and the comparison of infection properties of mutant and wild-type phages. Furthermore, using our new molecular field method, we will assess the distribution patterns of different subtypes of T7-like cyanophages from within the mix of all viruses in the oceans. The unique combination of innovative molecular methods with physiological experimentation and ecological sampling will provide significant insight into both the biological functionality behind the diversity within an ecologically relevant phage family and the selection pressures that have led to their diversification and evolution.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "PHAGEDIFF" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "PHAGEDIFF" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

PROGRESS (2019)

The Enemy of the Good: Towards a Theory of Moral Progress

Read More  

DISINTEGRATION (2019)

The Mass Politics of Disintegration

Read More  

SPA4AstroQIT (2019)

Broadband Quantum-Limited Parametric Amplifier for Astronomy and Quantum Information Technology

Read More