Opendata, web and dolomites

CellStretch SIGNED

A Cardiomyocyte Workout:Using Dielectric Elastomer Actuators for Mechanical Stimulation of in-vitro Cells

Total Cost €


EC-Contrib. €






 CellStretch project word cloud

Explore the words cloud of the CellStretch project. It provides you a very rough idea of what is the project "CellStretch" about.

mechanical    arrhythmia    impulse    perturbations    tissue    stretchers    mechanisms    stretchable    elastomer    performed    attached    propagation    closer    ideally    edge    imaging    dish    vitro    full    questions    cardiomyocytes    stretching    degree    die    treatment    inadequate    conduct    voltage    velocity    native    physiological    strengths    freedom    compliant    transparent    actuator    tackle    promise    cultures    cells    cellular    mechanically    living    strain    cardiovascular    cutting    approximation    sensitive    apparatus    fundamental    externally    optical    sued    transform    cellstretch    stretcher    platform    function    lacking    setup    speed    biological    vivo    deas    dynamic    cell    experimental    time    dielectric    dynamically    static    precise    host    rigid    device    hampered    suited    microscopy    environment    electrodes    precludes    death    manufacturing    integration    disease    dea    throughput    protocols    rate    experiments    leveraging    regarding    mechanosensitive    thereby    petri    modulated    flexibility    standard    compatible    levels    bio    stimulation    cardiac   

Project "CellStretch" data sheet

The following table provides information about the project.


Organization address
address: BATIMENT CE 3316 STATION 1
postcode: 1015

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Project website
 Total cost 187˙419 €
 EC max contribution 187˙419 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-03-01   to  2018-02-28


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

The CellStretch project will tackle fundamental questions regarding cardiac arrhythmia mechanisms by leveraging cutting-edge Dielectric Elastomer Actuator (DEA) technology. The development and implementation of a dynamic cell stretching platform using transparent, bio-compatible DEAs is proposed. Novel manufacturing methods of the platform, including the integration of highly stretchable and compliant electrodes, enable the precise control of an applied strain. Attached cells can thereby be mechanically modulated at a well-defined level and rate of stimulation. As the proposed device is transparent, the impact on the cells can be observed using standard optical microscopy protocols in real time. Typically, physiological studies on the cellular and tissue levels are performed in vitro with full control of the experimental environment. A rigid petri dish however, precludes addressing the mechanical degree of freedom. DEAs can transform the static environment of current in-vitro experiments into a dynamically strain-controlled setup. This is not only ideally suited to study the mechanosensitive response of cells, but is also a closer in-vitro approximation to the cells native in-vivo biological environment. The cell stretcher will be used to conduct experiments of mechanical perturbations on cardiomyocytes. Measurements will focus on the impulse propagation velocity and voltage-sensitive die imaging of cell cultures, as a function of externally applied mechanical strain. Such experiments are currently hampered by inadequate apparatus, lacking in speed, flexibility and throughput. The cell stretchers developed promise to enable a host of new experiments on living cells. Studies on cardiomyocytes will demonstrate the strengths of this technology and will be sued to tackle fundamental physiological questions related to arrhythmia mechanisms. In the long term, this can lead to improved treatment for cardiovascular disease, the number one cause of death in the EU.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "CELLSTRETCH" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email ( and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "CELLSTRETCH" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

InProSMod (2021)

Cholinergic and NMDAR-dependent recruitment of Layer 1 Interneuron shapes cortical motor Processing through network States Modulation

Read More  

BiMetaCat (2019)

Two Are Better Than One: Bimetallic Catalysts for the Conversion of Lignin-Derived Aryl-Ethers

Read More  

NeoPur (2019)

New treatments and novel diagnostic tests for neonatal seizures based on purinergic signaling.

Read More