Opendata, web and dolomites


Microtubule Dynamics during angiogenesis

Total Cost €


EC-Contrib. €






Project "MTUB-ANGIO" data sheet

The following table provides information about the project.


Organization address
postcode: 3584 CS

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Project website
 Total cost 177˙598 €
 EC max contribution 177˙598 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-09-01   to  2018-08-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITEIT UTRECHT NL (UTRECHT) coordinator 177˙598.00


 Project objective

Restoring normal vessel structure and function is now considered as a highly promising therapeutic opportunity for angiogenesis-related diseases, including cancer. Despite extensive use of microtubule targeting compounds in vascular-directed anticancer treatment, knowledge of the cellular mechanisms underlying microtubule regulation during angiogenesis is still elusive. By combining my previous experience in endothelial cell biology and the long term expertise of the host laboratory in microtubules dynamics as well as in high resolution imaging techniques, our project is aimed at studying microtubule dynamics and microtubule function in the precise context of sprouting angiogenesis. To achieve that goal, we propose to address the role of microtubule regulatory proteins using advanced high resolution live imaging of 3D culture of endothelial cells. We will identify endothelial specific MT regulators through expression, interaction and functional studies, assess their impact on microtubule dynamics during 3D tubulogenesis and validate their role both in the 3D morphogenesis model and in vivo, using zebrafish. This project is aimed at answering fundamental questions in the angiogenesis field as well as providing new opportunities for therapeutic strategies. At the same time, my experience in the laboratory of Dr Akhmanova will allow me to develop knowledge and skills in order to prepare me to reach a position of professional maturity.


year authors and title journal last update
List of publications.
2018 Maud Martin, Alexandra Veloso, Jingchao Wu, Eugene A Katrukha, Anna Akhmanova
Control of endothelial cell polarity and sprouting angiogenesis by non-centrosomal microtubules
published pages: , ISSN: 2050-084X, DOI: 10.7554/eLife.33864
eLife 7 2019-06-13

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "MTUB-ANGIO" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email ( and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "MTUB-ANGIO" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

NaWaTL (2020)

Narrative, Writing, and the Teotihuacan Language: Exploring Language History Through Phylogenetics, Epigraphy and Iconography

Read More  

PNAIC (2018)

Positive and Negative Asymmetry in Intergroup Contact: Its Impact on Linguistic Forms of Communication and Physiological Responses

Read More  

BirthControlEnvirons (2019)

Contraception meets the environment: everyday contraceptive practices, politics, and futures in a toxic age

Read More