STEPN-UP
Stilbene and entomopathogenic nematodes: Unlocking the potential
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0STEPN-UP project word cloud
Explore the words cloud of the STEPN-UP project. It provides you a very rough idea of what is the project "STEPN-UP" about.
Project "STEPN-UP" data sheet
The following table provides information about the project.
| Coordinator |
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
Organization address contact info |
| Coordinator Country | Ireland [IE] |
| Total cost | 175˙866 € |
| EC max contribution | 175˙866 € (100%) |
| Programme |
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility) |
| Code Call | H2020-MSCA-IF-2015 |
| Funding Scheme | MSCA-IF-EF-ST |
| Starting year | 2017 |
| Duration (year-month-day) | from 2017-01-01 to 2018-12-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK | IE (Cork) | coordinator | 175˙866.00 |
Map
Project objective
Bacteria frequently form intimate associations with a eukaryotic host where they may have critical roles in the development, behavior, and/or functions of their animal symbiont. While the underlying molecular mechanisms are poorly understood there is increasing evidence that the bacteria are employing proteins or molecules to send signals to their host. My goal is to understand the inter-kingdom signalling that occurs between a bacterium and its animal host using, as a model, the interaction between an entomopathogenic nematode (EPN) called Heterorhabditis and its symbiotic bacterium, Photorhabdus.
EPNs are soil-dwelling organisms that utilize a bacterial symbiont to kill their insect targets. Photorhabdus produces a bioactive secondary metabolite called stilbene (ST). ST is used as an antibiotic and a virulence factor. Furthermore, ST is required for nematode growth and development suggesting that ST may be an important inter-kingdom signalling molecule. In this vein, the proposed project will investigate fundamental aspects pertaining to host-symbiont evolution and interactions by: 1) investigating the evolutionary history of ST synthesis proteins, 2) determining the nematode response to ST, and 3) engineering increased ST production.
Aside from scientific advances, this fellowship would enable me to attend University College Cork (UCC) where beneficial training and knowledge will be obtained. For example, UCC provides training workshops on presentation skills, project management, and grant writing among others and aids in career management plans. Furthermore, I will learn new laboratory techniques and knowledge from this project. On the other hand, I will be able to bring my expertise in bacterial research to the host laboratory. This fellowship will have a significant impact on my career as an independent research scientist and will provide me opportunities to interact with the general public to enhance an overall knowledge of science.
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "STEPN-UP" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "STEPN-UP" are provided by the European Opendata Portal: CORDIS opendata.