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METAFLUIDICS SIGNED

Advanced toolbox for rapid and cost-effective functional metagenomic screening - microbiology meets microfluidics.

Total Cost €

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EC-Contrib. €

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Partnership

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 METAFLUIDICS project word cloud

Explore the words cloud of the METAFLUIDICS project. It provides you a very rough idea of what is the project "METAFLUIDICS" about.

screening    workflows    metagenome    throughput    hits    faster    library    technologies    platform   

Project "METAFLUIDICS" data sheet

The following table provides information about the project.

Coordinator
UNIVERSIDAD AUTONOMA DE MADRID 

Organization address
address: CALLE EINSTEIN 3 CIUDAD UNIV CANTOBLANCO RECTORADO
city: MADRID
postcode: 28049
website: http://www.uam.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 8˙808˙363 €
 EC max contribution 8˙808˙363 € (100%)
 Programme 1. H2020-EU.2.1.4. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Biotechnology)
 Code Call H2020-LEIT-BIO-2015-1
 Funding Scheme /RIA
 Starting year 2016
 Duration (year-month-day) from 2016-06-01   to  2020-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSIDAD AUTONOMA DE MADRID ES (MADRID) coordinator 1˙233˙729.00
2    THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE UK (CAMBRIDGE) participant 1˙120˙190.00
3    NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU NO (TRONDHEIM) participant 840˙357.00
4    NOVOZYMES A/S DK (BAGSVAERD) participant 821˙729.00
5    INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE FR (TOULOUSE) participant 722˙255.00
6    AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS ES (MADRID) participant 636˙282.00
7    UNIVERSIDAD DE ALICANTE ES (ALICANTE) participant 595˙600.00
8    PROZOMIX LIMITED UK (HALTWHISTLE) participant 546˙806.00
9    QIAGEN AARHUS AS DK (AARHUS) participant 463˙750.00
10    SINTEF AS NO (TRONDHEIM) participant 461˙247.00
11    BIOILIBERIS RESEARCH AND DEVELOPMENT SL ES (ARMILLA GRANADA) participant 460˙000.00
12    CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO PT (COIMBRA) participant 407˙590.00
13    STIFTELSEN SINTEF NO (TRONDHEIM) participant 291˙006.00
14    DROP-TECH LTD UK (Cambridge) participant 207˙820.00

Mappa

 Project objective

Metagenomes comprise enormous reservoirs coding for proteins with useful activities. Unfortunately, harvesting this reservoir is difficult, because useful candidates are rare and hidden in an overwhelming majority of irrelevant genes. Screening campaigns of metagenomic libraries thus require massive capital-expenditure for robotic systems and much manpower, making them expensive, slow and available to very few users. To enable valorisation of the potential of the metagenome, this project assembles an interdisciplinary and intersectoral consortium that will integrate a range of technologies into a platform designed to beat the odds of identifying library hits faster, more efficiently and by a wider user base. Exploration and exploitation of the metagenome will be made faster and more successful by (i) ultrahigh-throughput screening in picoliter droplets that dramatically lowers the cost per assay to well below 0.01 cents and allows throughput of 10e7 assays per hour; (ii) workflows that streamline and increase the yield of library construction and functional expression and (iii) workflows for efficient bioinformatic analysis of hits based on user-friendly software solutions for metagenome analysis. Emphasis is put on technologies that are straightforwardly implemented in non-specialist labs, maximising the impact of METAFLUIDICS. This platform will be used to identify enzymes for biosynthesis of therapeutic small molecules, for green bioenergy conversion, bioremediation, food chemistry and other industrial applications

 Work performed, outcomes and results:  advancements report(s) 

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The information about "METAFLUIDICS" are provided by the European Opendata Portal: CORDIS opendata.

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