Opendata, web and dolomites

FUTURE

Re-factoring Pseudomonas putida for biosynthesis of vaIue-added polymers from cellulosic waste

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 FUTURE project word cloud

Explore the words cloud of the FUTURE project. It provides you a very rough idea of what is the project "FUTURE" about.

synthetic    context    effort    biocatalytic    versatile    valuable    added    engineered    engineering    refactoring    fundamentals    forming    efficient    environmental    never    viability    organic    serve    industrial    native    biotechnological    cellulolytic    compromising    pseudomonas    platform    displaying    surface    abundant    enzymatic    saprophytic    sugars    metabolism    displayed    lignocellulose    vac    skills    rational    biology    establishing    microorganisms    negative    workhorse    earth    bacteria    recalcitrant    kt2440    bacterial    cellulosic    metabolic    construct    bio    solved    nanomachines    aromatics    expanding    generating    biological    cellulosomes    putida    waste    compounds    constituent    substrates    wastes    agricultural    chemicals    roadmap    tools    enrichment    functions    monomeric    designer    desired    biopolymers    components    biofuel    cell    utilize    model    biosynthesis    host    missing    successfully    yeast    single    certain    aromatic    physiological    qualities    corporate    bacterium    laboratory    gram    massive    orchestration    economy    cheap    hinders    pretreatment   

Project "FUTURE" data sheet

The following table provides information about the project.

Coordinator
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS 

Organization address
address: CALLE SERRANO 117
city: MADRID
postcode: 28006
website: http://www.csic.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website http://wwwuser.cnb.csic.es/
 Total cost 170˙121 €
 EC max contribution 170˙121 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-10-01   to  2018-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) coordinator 170˙121.00

Map

 Project objective

Lignocellulose is the most abundant organic matter on Earth and important constituent of agricultural and industrial wastes. Lignocellulose-derived monomeric sugars and aromatic compounds can serve as a cheap substrates for biotechnological production of numerous value-added chemicals (VAC). However, a well-defined bacterial platform that could efficiently utilize lignocellulose for biosynthesis of VAC in a single step is still missing. The saprophytic bacterium Pseudomonas putida KT2440, a robust laboratory workhorse with versatile metabolism, has wide potential to utilize lignocellulose-derived sugars and aromatics for VAC formation. But the need for enzymatic pretreatment of the recalcitrant lignocellulose components hinders the development of a cost-effective processes. This challenge could be solved by expanding the biocatalytic functions of P. putida using cellulosomes, efficient enzymatic nanomachines displayed on the surface of certain cellulolytic microorganisms. Synthetic cellulosomes were successfully engineered in biofuel-generating yeast, but never in a Gram-negative bacterium. The applicant will adopt state-of-the-art approaches and tools of synthetic biology, systems biology and metabolic engineering in order to construct P. putida displaying designer cellulosomes and forming valuable biopolymers directly from cellulosic waste. This task requires a rational orchestration of distinct physiological features of the host in order to achieve the desired qualities without compromising cell viability. In this context, the study will also propose a roadmap for massive refactoring and enrichment of native metabolic properties of environmental bacteria. Thus, the project will not only allow the applicant to enhance his research skills, but will also contribute to both understanding fundamentals of model biological systems and corporate effort aimed at establishing FUTURE knowledge-based bio-economy in Europe.

 Publications

year authors and title journal last update
List of publications.
2018 Pavel Dvořák, Víctor de Lorenzo
Refactoring the upper sugar metabolism of Pseudomonas putida for co-utilization of cellobiose, xylose, and glucose
published pages: 94-108, ISSN: 1096-7176, DOI: 10.1016/j.ymben.2018.05.019
Metabolic Engineering 48 2019-06-13
2017 Pavel Dvořák, Pablo I. Nikel, Jiří Damborský, Víctor de Lorenzo
Bioremediation 3 . 0 : Engineering pollutant-removing bacteria in the times of systemic biology
published pages: 845-866, ISSN: 0734-9750, DOI: 10.1016/j.biotechadv.2017.08.001
Biotechnology Advances 35/7 2019-06-13

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "FUTURE" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "FUTURE" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

ReSOLeS (2019)

New Reconfigurable Spectrum Optical Fibre Laser Sources

Read More  

ICARUS (2020)

Information Content of locAlisation: fRom classical to qUantum Systems

Read More  

TOPOCIRCUS (2019)

Simulations of Topological Phases in Superconducting Circuits

Read More