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NanoSil4Cancer

Smart Multifunctional silica-based Nanoparticles for Targeted Therapy

Total Cost €

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EC-Contrib. €

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Partnership

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 NanoSil4Cancer project word cloud

Explore the words cloud of the NanoSil4Cancer project. It provides you a very rough idea of what is the project "NanoSil4Cancer" about.

chemotherapy    formulated    pct    active    acquire    folic    saving    medical    communication    dosage    minimizing    receptor    folate    interests    business    vehicles    minimize    pro    buy    attractiveness    molecules    nevertheless    sme    therapy    customers    customer    device    feasibility    90    290b    proprietary    fr    patients    acid    sensitive    search    market    competence    therapeutic    ep06745236    thomson    healthcare    silica    cells    commercial    patent    nano    environmental    mesoporous    13511    intracellular    final    release    epo    missing    normal    lowering    efficacy    pharma    limited    dramatically    platform    innovative    report    prototypes    sectorial    sparing    nanosil4cancer    bortezomib    ph    compartments    nanoparticles    agents    marketing    released    cancer    toxicity    internalized    accelerate    antitumor    big    drug    nanotechnologies    trend    technologies    individuate    overexpressing    drugs    smart    depends    strategical    optimized    prototype    stakeholder    adherence   

Project "NanoSil4Cancer" data sheet

The following table provides information about the project.

Coordinator
NANOSILICAL DEVICES SRL 

Organization address
address: VIA PIETRO BUCCI CUBO 44A
city: RENDE
postcode: 87036
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website http://www.nanosilicaldevices.com/it/
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2016
 Duration (year-month-day) from 2016-09-01   to  2017-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    NANOSILICAL DEVICES SRL IT (RENDE) coordinator 50˙000.00

Map

 Project objective

NanoSil4Cancer project will be able to accelerate the uptake of nanotechnologies, by developing, mesoporous silica-based prototypes of nano-vehicles, according to an innovative and proprietary approach (EP06745236), active in smart chemotherapy. This is aimed to minimize toxicity and the side effects of the traditional antitumor agents and to increase their therapeutic potential. This technology platform enables customers’ molecules to be formulated as pH–sensitive pro-drugs and introduced in smart nanoparticles able to reach the intracellular compartments of cancer cells where the drug is released. Development of new prototypes will lead to new patent applications. Recently we have developed and optimized a device, provided with folic acid, able to manage bortezomib release in cancer cells overexpressing folate receptor, FR (PCT-13511). The nanoparticles are only recognized and internalized by FR overexpressing cancer cells, where they release the drug, sparing normal cells. Nevertheless, our technology is general, not limited to a specific prototype, but depends on customer's needs, market and final users' needs. The feasibility study will individuate strategical market interests to address the prototypes production as business opportunities for our SME. Market trend and the role of Big Pharma will be defined to identify commercial partners and stakeholder to be involved in the project. We will buy sectorial report, we will use patent search such as EPO and Thomson, we will acquire missing competence in marketing and communication. The approach will represent a strong step forward in chemotherapy, improving the efficacy, lowering drug dosage (thus minimizing side effects for cancer patients and environmental impact), other than dramatically lowering EU Healthcare costs (up to 80-90% saving on non-adherence to the therapy costs, estimated in $290B/year), allowing Europe to increase its attractiveness in the field of innovative medical technologies.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "NANOSIL4CANCER" project.

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The information about "NANOSIL4CANCER" are provided by the European Opendata Portal: CORDIS opendata.

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