Opendata, web and dolomites


Towards an objective and quantitative Assessment of human Corneal Transparency

Total Cost €


EC-Contrib. €






 TACT project word cloud

Explore the words cloud of the TACT project. It provides you a very rough idea of what is the project "TACT" about.

ocular    subtle    position    diagnosis    validating    care    quantify    ageing    slit    ease    corneal    surgery    investigations    capability    de    spur    acuity    transparency    worldwide    treatment    subjectively    infections    focal    physics    institut    improvements    anterior    lacks    segment    usually    imaging    full    penetration    ffoct    avenues    transparencies    polarized    researcher    optical    coherence    langevin    light    clinical    deep    media    drawbacks    excellent    monitor    biomicroscopy    direct    ophthalmology    aside    trauma    continue    monitored    critical    interface    lack    inherent    biomicroscope    lamp    register    innovations    objectively    carry    auspices    basic    la    vision    patient    opacity    alone    qualitative    tool    unmet    characterization    hence    modalities    wavelength    matrix    independent    candidate    resolve    prevention    compromised    quantitative    illumination    people    reproducibility    blindness    causes    ideal    subjective    practical    tomography    qualitatively    resolution    pathologies    cornea    investigates    dependent    host    scattering    fellowship    visual    poor    million   

Project "TACT" data sheet

The following table provides information about the project.


There are not information about this coordinator. Please contact Fabio for more information, thanks.

 Coordinator Country France [FR]
 Project website
 Total cost 173˙076 €
 EC max contribution 173˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-RI
 Starting year 2017
 Duration (year-month-day) from 2017-03-01   to  2019-02-28


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    SORBONNE UNIVERSITE FR (PARIS) coordinator 173˙076.00


 Project objective

Visual acuity is dependent upon the transparency of the cornea. Corneal transparency can be compromised by various pathologies, infections, trauma, ageing, and surgery, all of which result in increased light scattering. Lack of ocular anterior segment transparency is the leading cause of blindness worldwide, with corneal causes alone affecting over 10 million people. In current clinical ophthalmology practice, corneal transparency is usually monitored subjectively and qualitatively via direct focal illumination using a slit-lamp biomicroscope. Aside from inherent subjective and qualitative drawbacks, including poor reproducibility, this method lacks the capability to register and resolve changes in opacity that may be subtle. Hence, there is a critical need for a reliable and practical tool to objectively quantify, characterize, and monitor corneal transparency towards effective prevention, diagnosis, and treatment. The overall objective of this research programme is to address this unmet need by developing and validating advanced concepts and novel imaging modalities tailored to the needs of cornea assessment. The programme investigates (1) Quantitative Polarized Slit-lamp Biomicroscopy, (2) Multi-Wavelength Full-Field Optical Coherence Tomography (FFOCT), and (3) Multi-Illumination Matrix FFOCT; all enabling ease of use, high resolution, and deep light-penetration characterization and imaging. The candidate will be in an excellent position to carry out the programme under the auspices of the ideal host (Institut de la Vision) and the ideal partner (Institut Langevin). The research will enhance our basic understanding of corneal transparency as well as lead to major changes and improvements in patient care and management. It will, moreover, open new avenues and spur further investigations of ocular media transparencies. The Fellowship will enable the candidate to continue innovations at the interface of physics and ophthalmology as an independent researcher.


year authors and title journal last update
List of publications.
2018 Viacheslav Mazlin, Peng Xiao, Eugénie Dalimier, Kate Grieve, Kristina Irsch, José-Alain Sahel, Mathias Fink, A. Claude Boccara
In vivo high resolution human corneal imaging using full-field optical coherence tomography
published pages: 557, ISSN: 2156-7085, DOI: 10.1364/BOE.9.000557
Biomedical Optics Express 9/2 2019-05-23
2019 Kristina Irsch, Kate Grieve, Marie Borderie, Djida Ghoubay, Cristina Georgeon, Vincent Borderie
Full-field Optical Coherence Microscopy for Histology-like Analysis of Stromal Features in Corneal Grafts
published pages: , ISSN: 1940-087X, DOI:
JoVE 2019-05-23

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The information about "TACT" are provided by the European Opendata Portal: CORDIS opendata.

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