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INdividual Vascular SignaTure: A new machine learning tool to aid personalised management of risk for cardiovascular disease

Total Cost €


EC-Contrib. €






 INVeST project word cloud

Explore the words cloud of the INVeST project. It provides you a very rough idea of what is the project "INVeST" about.

provider    decision    follow    lifestyle    describes    prevention    invaluable    model    drug    asset    classifiers    clinical    interventions    classification    community    healthy    cvd    personalised    dynamic    person    groups    pathological    pathology    advice    healthcare    diseases    first    eye    provocation    started    participating    detected    building    background    distinguishing    aid    assessments    accurately    invest    fellow    earlier    talented    creates    vessel    disease    care    microvascular    cardiovascular    tools    therapies    progress    efficient    improvements    brings    diagnoses    trained    science    medicine    encompassing    multidisiplinary    mortality    imaging    informatics    young    effectiveness    intervention    treatments    report    prediction    worldwide    variation    computer    predicts    statistical    time    individual    portfolio    invasive    profile    health    benefits    retinal    sensitive    vascular    disability    risk    signature    apparatus    mathematical   

Project "INVeST" data sheet

The following table provides information about the project.


Organization address
postcode: B4 7ET

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-09-02   to  2018-09-01


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ASTON UNIVERSITY UK (BIRMINGHAM) coordinator 183˙454.00


 Project objective

Health authorities in the EU have started to investigate the benefits of personalised health risk assessments and interventions in many diseases including cardiovascular disease (CVD), a worldwide leading cause of disability and mortality. Personalised health care aims at better diagnoses and earlier interventions, more efficient drug development and more effective therapies, thus providing better tools for clinical decision making and disease prevention.

The INVeST project will produce for the first time a method that creates an individual vascular signature that is sensitive enough to aid early prediction and personalised intervention in CVD as well as treatments follow-up. INVeST will be able to provide the above through the following steps: (1) by participating in a short non-invasive eye test, any person can be provided with their own INVeST report, based on which lifestyle advice can be provided by a trained healthcare provider to improve their health and (2) if risk or CVD pathology is detected and intervention is applied, INVeST can help provide a progress report on the personalised intervention effectiveness and health improvements.

The Fellow will (1) develop a mathematical model that describes each individual’s real-time retinal microvascular dynamic response to provocation, (2) identify and apply novel classifiers capable of accurately distinguishing between variation of healthy responses and pathological cases, (3) develop the mathematical apparatus, which based on the individual retinal vessel profile predicts the (individual) risk of developing CVD.

INVeST brings together a talented young Fellow with background in computer science with three well-known groups in vascular imaging, computer science and health informatics. Following INVeST, with a portfolio encompassing personalised medicine, statistical model building, classification and CVD risk prediction, the Fellow will be an invaluable asset to the European multidisiplinary research community.


year authors and title journal last update
List of publications.
2019 András M Joó, Anikó Ekárt, Emily Scarpello, Konstantin Gugleta, Selim Orguel, Leopold Schmetterer,, Doina Gherghel
Modelling Retinal Vessel Flicker Response
published pages: , ISSN: , DOI:
2018 Andras Joo, Emily Scarpello, Aniko Ekart, Doina Gherghel
Effective visualization of Retinal Vessel Analysis (RVA) data
published pages: , ISSN: , DOI:

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The information about "INVEST" are provided by the European Opendata Portal: CORDIS opendata.

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