Explore the words cloud of the Pectin project. It provides you a very rough idea of what is the project "Pectin" about.
The following table provides information about the project.
UNIVERSITY OF NEWCASTLE UPON TYNE
|Coordinator Country||United Kingdom [UK]|
|Total cost||195˙454 €|
|EC max contribution||195˙454 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2016-04-01 to 2018-03-31|
Take a look of project's partnership.
|1||UNIVERSITY OF NEWCASTLE UPON TYNE||UK (NEWCASTLE UPON TYNE)||coordinator||195˙454.00|
The large bowel is colonized by a community of microbes, the microbiota, which has a significant impact on human health and nutrition. The major nutrients available to these organisms are dietary glycans. Thus, glycan-based dietary and nutraceutical strategies can, potentially, be deployed to encourage the dominance of beneficial microbes within the microbiota, ensuring the microbial ecosystem has a positive influence on human health. This approach, however, is greatly restricted by a critical lack of understanding of the mechanisms by which complex glycans are metabolized by the microbiota. Significantly, the wealth of genomic/metagenomic microbiota sequence data now available, presents an exciting and unparalleled opportunity to make decisive advances in our understanding of glycan metabolism in the human large bowel. This project seeks to capitalize on this genomic information, in harness with recent functional data from the host laboratory, to understand the mechanisms by which pectin, the major component of the human diet that is metabolized by the microbiota. The data will inform novel prebiotic and probiotic strategies to maximise the impact of the microbiota on human health. At a generic level, understanding glycan resource allocation in the microbiota represents an excellent system for studying the molecular mechanisms that lead to the evolution of novel glycanase functions, which, in turn, will provide a robust functional context to bioinformatic-based predictive biology. The fellow is Italian and has recently completed her PhD student at the University of Lisboa, Portugal, with the project FP7 Initial Training Network termed WallTraC. The fellow has experience in high throughput protein expression, enzyme activity screening and structural biology. At Newcastle University she will have the opportunity to develop skills in adanced mechanistic enzymology, anaerobic microbiology, bioinformatics, in vivo bacterial genetic manipulation and microbial ecology.
|year||authors and title||journal||last update|
Immacolata Venditto, Ana S. Luis, Maja Rydahl, Julia SchÃ¼ckel, VÃ¢nia O. Fernandes, Silvia Vidal-Melgosa, Pedro Bule, Arun Goyal, Virginia M. R. Pires, Catarina G. Dourado, LuÃs M. A. Ferreira, Pedro M. Coutinho, Bernard Henrissat, J. Paul Knox, Arnaud BaslÃ©, Shabir Najmudin, Harry J. Gilbert, William G. T. Willats, Carlos M. G. A. Fontes
Complexity of the Ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition
published pages: 7136-7141, ISSN: 0027-8424, DOI: 10.1073/pnas.1601558113
|Proceedings of the National Academy of Sciences 113/26||2019-06-13|
Didier Ndeh, Artur Rogowski, Alan Cartmell, Ana S. Luis, Arnaud BaslÃ©, Joseph Gray, Immacolata Venditto, Jonathon Briggs, Xiaoyang Zhang, Aurore Labourel, Nicolas Terrapon, Fanny Buffetto, Sergey Nepogodiev, Yao Xiao, Robert A. Field, Yanping Zhu, Malcolm A. Oâ€™Neill, Breeanna R. Urbanowicz, William S. York, Gideon J. Davies, D. Wade Abbott, Marie-Christine Ralet, Eric C. Martens, Bernard Henrissat, Harry J. Gilbert
Complex pectin metabolism by gut bacteria reveals novel catalytic functions
published pages: 65-70, ISSN: 0028-0836, DOI: 10.1038/nature21725
Ana S. Luis, Jonathon Briggs, Xiaoyang Zhang, Benjamin Farnell, Didier Ndeh, Aurore Labourel, Arnaud BaslÃ©, Alan Cartmell, Nicolas Terrapon, Katherine Stott, Elisabeth C. Lowe, Richard McLean, Kaitlyn Shearer, Julia SchÃ¼ckel, Immacolata Venditto, Marie-Christine Ralet, Bernard Henrissat, Eric C. Martens, Steven C. Mosimann, D. Wade Abbott, Harry J. Gilbert
Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides
published pages: 210-219, ISSN: 2058-5276, DOI: 10.1038/s41564-017-0079-1
|Nature Microbiology 3/2||2019-06-13|
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "PECTIN" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (firstname.lastname@example.org) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "PECTIN" are provided by the European Opendata Portal: CORDIS opendata.
Positive and Negative Asymmetry in Intergroup Contact: Its Impact on Linguistic Forms of Communication and Physiological ResponsesRead More
Charles IV and the power of marvellous objectsRead More
Multi-color and single-molecule fluorescence imaging of intraflagellar transport in the phasmid chemosensory cilia of C. ElegansRead More