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MarPipe SIGNED

Improving the flow in the pipeline of the next generation of marine biodiscovery scientists

Total Cost €

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EC-Contrib. €

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Partnership

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 MarPipe project word cloud

Explore the words cloud of the MarPipe project. It provides you a very rough idea of what is the project "MarPipe" about.

trained    careers    skills    antarctic    marine    participation    esrs    toxicity    economic    microdish    students    joint    clinical    irl    envisage    phds    uniabdn    bioactive    scientists    eurofleet    ecoast    uk    exchange    chemodiversity    molecules    pharmasea    bottlenecks    scientific    industry    public    intense    sectoral    11    cnr    szn    phd    entrepreneurship    ibp    natural    conscious    train    capacity    pipeline    phases    courses    strains    themes    isolation    cover    socio    nl    context    biodiscovery    innovation    deep    creation    inter    enhanced    collected    countries    outcome    policy    potent    anticancer    originating    sub    biologically    5000m    final    geomar    yields    compounds    antimicrobial    explore    medina    italbiotec    discovery    microbial    start    networking    world    variety    kuleuven    plan    active    transferrable    overcome    leaders    academia    company    rates    bioactivity    training    events    ucc    toward    samples    organisms    antibiotic    academic    marpipe    sea    drug    uit   

Project "MarPipe" data sheet

The following table provides information about the project.

Coordinator
CONSIGLIO NAZIONALE DELLE RICERCHE 

Organization address
address: PIAZZALE ALDO MORO 7
city: ROMA
postcode: 185
website: www.cnr.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website http://www.marpipe.eu
 Total cost 2˙853˙005 €
 EC max contribution 2˙853˙005 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2016
 Funding Scheme MSCA-ITN-ETN
 Starting year 2016
 Duration (year-month-day) from 2016-11-01   to  2020-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CONSIGLIO NAZIONALE DELLE RICERCHE IT (ROMA) coordinator 258˙061.00
2    UNIVERSITETET I TROMSOE - NORGES ARKTISKE UNIVERSITET NO (TROMSO) participant 286˙275.00
3    THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN UK (ABERDEEN) participant 273˙287.00
4    UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK IE (Cork) participant 265˙674.00
5    CONSORZIO ITALBIOTEC IT (MILANO) participant 258˙061.00
6    STAZIONE ZOOLOGICA ANTON DOHRN IT (NAPOLI) participant 258˙061.00
7    WAGENINGEN UNIVERSITY NL (WAGENINGEN) participant 255˙374.00
8    KATHOLIEKE UNIVERSITEIT LEUVEN BE (LEUVEN) participant 250˙560.00
9    HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL DE (KIEL) participant 249˙216.00
10    FUNDACION CENTRO DE EXCELENCIA EN INVESTIGACION DE MEDICAMENTOS INNOVADORES EN ANDALUCIA ES (ARMILLA GRANADA) participant 247˙872.00
11    ABS INTERNATIONAL BE (BRUGES) participant 128˙760.00
12    ECOAST BE (OOSTENDE) participant 121˙800.00
13    MICRODISH BV NL (BADHOEVEDORP) participant 0.00
14    ALTA RICERCA E SVILUPPO IN BIOTECNOLOGIE SRLU IT (SIENA) partner 0.00

Map

 Project objective

MarPipe is a consortium of 11 partners (IBP-CNR, SZN, UiT, UNIABDN, GEOMAR, KULeuven, UCC, eCOAST, MEDINA, MicroDish, Italbiotec) based in 8 countries (I, N, UK, D, B, IRL, E, NL), including 3 from the non-academic sector. We will train 11 ESRs in marine drug-discovery, providing these researchers with unique skills toward becoming world leaders in this research field and to advance their careers in academia or industry. MarPipe PhDs will be trained in a programme including training-by-research, joint courses of technical, scientific and transferrable skills, active participation to public scientific events, and an intense inter-sectoral networking exchange plan. Marine organisms have the capacity to produce a variety of biologically potent natural products, including antibiotic and anticancer compounds. MarPipe aims at further development of antimicrobial and anticancer lead compounds originating from a previous EU project (PharmaSea), and will also explore the bioactivity of deep-sea samples (5000m) collected during the recent Eurofleet-2 project in the sub-Antarctic. The PhD students will thus be involved in all phases of the drug discovery pipeline, from isolation of new microbial strains to pre-clinical development of lead compounds. Importantly, they will also be trained to overcome existing bottlenecks in the field, e.g. low yields and low chemodiversity, isolation of known compounds, toxicity of compounds. The discovery rates of new bioactive antimicrobial and anticancer molecules will be enhanced through 11 PhD projects that cover all phases of the biodiscovery pipeline. As a final outcome of the project, we envisage the creation of a marine biodiscovery start-up company, which will include most of the MarPipe partners. The scientists of the future will be trained to become conscious about the socio-economic and policy context of their work, since several specific MarPipe PhD projects focus on legal, policy, innovation and entrepreneurship themes.

 Deliverables

List of deliverables.
Scientific paper on legal and policy framework applicable to marine scientific research in ABNJ Documents, reports 2020-03-06 18:03:07
Project meetings Other 2020-03-06 18:03:07
Completion of fellows recruitment Other 2020-03-06 18:03:07
Secondment reports Documents, reports 2020-03-06 18:03:07
SSC and SCT activities Other 2020-03-06 18:03:07
Review paper on the governance of (marine) bioprospecting Documents, reports 2020-03-06 18:03:07
Dissemination Other 2020-03-06 18:03:07
Individual CDP Documents, reports 2020-03-06 18:03:07
Website Demonstrators, pilots, prototypes 2020-03-06 18:03:07

Take a look to the deliverables list in detail:  detailed list of MarPipe deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Yannik K.-H. Schneider, Kine Ø. Hansen, Johan Isaksson, Sara Ullsten, Espen H. Hansen, Jeanette Hammer Andersen
Anti-Bacterial Effect and Cytotoxicity Assessment of Lipid 430 Isolated from Algibacter sp.
published pages: 3991, ISSN: 1420-3049, DOI: 10.3390/molecules24213991
Molecules 24/21 2020-03-23
2019 Kevin A. Martínez, Chiara Lauritano, Dana Druka, Giovanna Romano, Teresa Grohmann, Marcel Jaspars, Jesús Martín, Caridad Díaz, Bastien Cautain, Mercedes de la Cruz, Adrianna Ianora, Fernando Reyes
Amphidinol 22, a New Cytotoxic and Antifungal Amphidinol from the Dinoflagellate Amphidinium carterae
published pages: 385, ISSN: 1660-3397, DOI: 10.3390/md17070385
Marine Drugs 17/7 2020-03-06
2019 Arianna Giusti, Xuan-Bac Nguyen, Stanislav Kislyuk, Mélanie Mignot, Cecilia Ranieri, Johan Nicolaï, Marlies Oorts, Xiao Wu, Pieter Annaert, Noémie De Croze, Marc Léonard, Annelii Ny, Deirdre Cabooter, Peter de Witte
Safety Assessment of Compounds after In Vitro Metabolic Conversion Using Zebrafish Eleuthero Embryos
published pages: 1712, ISSN: 1422-0067, DOI: 10.3390/ijms20071712
International Journal of Molecular Sciences 20/7 2020-03-06
2018 Stefano Romano, Stephen Jackson, Sloane Patry, Alan Dobson
Extending the “One Strain Many Compounds” (OSMAC) Principle to Marine Microorganisms
published pages: 244, ISSN: 1660-3397, DOI: 10.3390/md16070244
Marine Drugs 16/7 2020-03-06
2018 Mercedes Pérez-Bonilla, Daniel Oves-Costales, Mercedes de la Cruz, Maria Kokkini, Jesús Martín, Francisca Vicente, Olga Genilloud, Fernando Reyes
Phocoenamicins B and C, New Antibacterial Spirotetronates Isolated from a Marine Micromonospora sp.
published pages: 95, ISSN: 1660-3397, DOI: 10.3390/md16030095
Marine Drugs 16/3 2020-03-06
2018 Fortunato Palma Esposito, Colin J. Ingham, Raquel Hurtado-Ortiz, Chantal Bizet, Deniz Tasdemir, Donatella de Pascale
Isolation by Miniaturized Culture Chip of an Antarctic bacterium Aequorivita sp. with antimicrobial and anthelmintic activity
published pages: e00281, ISSN: 2215-017X, DOI: 10.1016/j.btre.2018.e00281
Biotechnology Reports 20 2020-03-06
2018 Kevin Martínez Andrade, Chiara Lauritano, Giovanna Romano, Adrianna Ianora
Marine Microalgae with Anti-Cancer Properties
published pages: 165, ISSN: 1660-3397, DOI: 10.3390/md16050165
Marine Drugs 16/5 2020-03-06
2018 Delphine Parrot, Stefano Papazian, Daniel Foil, Deniz Tasdemir
Imaging the Unimaginable: Desorption Electrospray Ionization – Imaging Mass Spectrometry (DESI-IMS) in Natural Product Research
published pages: 584-593, ISSN: 0032-0943, DOI: 10.1055/s-0044-100188
Planta Medica 84/09/10 2020-03-06

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