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FBI SIGNED

Multimodal, Functional Bio-Photonic Imaging

Total Cost €

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EC-Contrib. €

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Partnership

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 FBI project word cloud

Explore the words cloud of the FBI project. It provides you a very rough idea of what is the project "FBI" about.

therapy    commercial    mechanisms    industry    standalone    academic    shown    said    disease    photonic    treatment    free    respectively    scanning    proposes    onset    forming    network    education    depending    tomography    optoacoustic    time    recurrence    fosters    simultaneously    limited    combine    feasible    invasive    sources    barriers    techniques    imaging    earlier    multimodal    analysed    biomedical    contrast    endoscopy    detection    intrinsic    translating    coherence    issue    integration    grading    efficient    15    world    biological    unmet    morphological    modalities    rates    educating    components    lesions    significantly    outcomes    translation    lack    diagnosis    optical    suspicious    label    photon    clinics    raman    interdisciplinary    combining    solutions    companies    staging    biochemical    sciences    relations    trained    huge    platform    biomarker    capture    laser    esrs    clinical    restricted    endoscopes    spectroscopy    accordingly    microangiography    fbi   

Project "FBI" data sheet

The following table provides information about the project.

Coordinator
DANMARKS TEKNISKE UNIVERSITET 

Organization address
address: ANKER ENGELUNDSVEJ 1 BYGNING 101 A
city: KGS LYNGBY
postcode: 2800
website: www.dtu.dk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Denmark [DK]
 Project website https://fbi-itn.eu/
 Total cost 3˙902˙716 €
 EC max contribution 3˙902˙716 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2016
 Funding Scheme MSCA-ITN-ETN
 Starting year 2016
 Duration (year-month-day) from 2016-10-01   to  2020-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    DANMARKS TEKNISKE UNIVERSITET DK (KGS LYNGBY) coordinator 580˙163.00
2    MEDIZINISCHE UNIVERSITAET WIEN AT (WIEN) participant 767˙802.00
3    ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE CH (LAUSANNE) participant 530˙453.00
4    TECHNISCHE UNIVERSITEIT EINDHOVEN NL (EINDHOVEN) participant 510˙748.00
5    TECHNISCHE UNIVERSITAET MUENCHEN DE (MUENCHEN) participant 498˙432.00
6    NKT PHOTONICS A/S DK (BIRKEROD) participant 290˙081.00
7    PHILIPS ELECTRONICS NEDERLAND BV NL (EINDHOVEN) participant 255˙374.00
8    ITHERA MEDICAL GMBH DE (MUNCHEN) participant 249˙216.00
9    EKSPLA UAB LT (VILNIUS) participant 220˙442.00
10    FEMTOLASERS PRODUKTIONS GMBH AT (KORNEUBURG) participant 0.00
11    ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM NL (AMSTERDAM) partner 0.00
12    ALBERT-LUDWIGS-UNIVERSITAET FREIBURG DE (FREIBURG) partner 0.00
13    CARL ZEISS AG DE (OBERKOCHEN) partner 0.00
14    IMASONIC SAS FR (VORAY SUR L'OGNON) partner 0.00
15    SMART PHOTONICS BV NL (EINDHOVEN) partner 0.00

Map

 Project objective

FBI fosters education of ESRs on an emerging, multimodal imaging platform and its translation into clinical and biological applications. In FBI, 15 ESRs are trained at world-leading European academic institutions and companies, thus forming strong interdisciplinary relations between industry, technical sciences and clinical end-users.

Optical imaging has huge potential to address unmet clinical needs by combining non-invasive and real-time capture of biomedical information; thus enabling earlier onset of treatment, reduced therapy costs, reduced recurrence rates, and improved clinical outcomes. Up to now, optical modalities were applied as standalone techniques each targeting one biomarker. Recently it has been shown that diagnosis is significantly improved by combining different contrast mechanisms simultaneously in a multimodal approach, i.e., staging and grading of lesions is feasible.

FBI proposes to combine a selection of modalities depending on the targeted disease. Suspicious lesions are analysed with optical coherence tomography, optoacoustic tomography, multi-photon tomography, and Raman spectroscopy to provide morphological, label-free microangiography, and intrinsic biochemical information, respectively. An important issue is the need for endoscopy: combining said modalities into endoscopes is challenging due to the integration of different imaging concepts, scanning and detection methods, and laser sources. Accordingly, there is a huge need for effectively translating these technical solutions to industry and clinics, which traditionally is restricted by lack of understanding of applications or limited knowledge of new technology.

All these barriers are addressed by FBI through research and development of novel photonic components and systems, through educating ESRs in understanding clinical, biological and commercial challenges, and through developing tailored technical solutions and efficient translation of technology within a strong network.

 Deliverables

List of deliverables.
Websites (external and internal for data sharing) Websites, patent fillings, videos etc. 2020-04-08 10:01:22
Mid Term report Documents, reports 2020-04-08 10:01:22
Tissue classification technology based on OCT and its combination with US Documents, reports 2020-04-08 10:01:22
Compact broadband Ti:sapphire laser technology incorporating new pump sources Documents, reports 2020-04-08 10:01:22
Progress Report Documents, reports 2020-04-08 10:01:22

Take a look to the deliverables list in detail:  detailed list of FBI deliverables.

 Publications

year authors and title journal last update
List of publications.
2020 Mikael T. Erkkilä, David Reichert, Nancy Hecker-Denschlag, Marco Wilzbach, Christoph Hauger, Rainer A. Leitgeb, Johanna Gesperger, Barbara Kiesel, Thomas Roetzer, Georg Widhalm, Wolfgang Drexler, Angelika Unterhuber, Marco Andreana
Surgical microscope with integrated fluorescence lifetime imaging for 5-aminolevulinic acid fluorescence-guided neurosurgery
published pages: 1, ISSN: 1083-3668, DOI: 10.1117/1.jbo.25.7.071202
Journal of Biomedical Optics 25/07 2020-04-08
2020 David Reichert, Mikael T. Erkkilä, Gerhard Holst, Nancy Hecker-Denschlag, Marco Wilzbach, Christoph Hauger, Wolfgang Drexler, Johanna Gesperger, Barbara Kiesel, Thomas Roetzer, Angelika Unterhuber, Georg Widhalm, Rainer A. Leitgeb, Marco Andreana
Towards real-time wide-field fluorescence lifetime imaging of 5-ALA labeled brain tumors with multi-tap CMOS cameras
published pages: 1598, ISSN: 2156-7085, DOI: 10.1364/boe.382817
Biomedical Optics Express 11/3 2020-04-08
2020 Fabian Placzek, Eliana Cordero Bautista, Simon Kretschmer, Lara M. Wurster, Florian Knorr, Gerardo González-Cerdas, Mikael T. Erkkilä, Patrick Stein, Çağlar Ataman, Gregers G. Hermann, Karin Mogensen, Thomas Hasselager, Peter E. Andersen, Hans Zappe, Jürgen Popp, Wolfgang Drexler, Rainer A. Leitgeb, Iwan W. Schie
Morpho-molecular ex vivo detection and grading of non-muscle-invasive bladder cancer using forward imaging probe based multimodal optical coherence tomography and Raman spectroscopy
published pages: , ISSN: 0003-2654, DOI: 10.1039/c9an01911a
The Analyst 2020-04-08
2017 Rastko Pajković, Kevin Williams, Erwin Bente
Tuning of an integrated tunable laser for swept source optical coherence tomography Tuning of an Integrated Tunable Laser for Swept Source Optical Coherence Tomography
published pages: 164-167, ISSN: , DOI:
Tuning of an integrated tunable laser for swept source optical coherence tomography 2020-04-08
2019 Hailong He, Antonios Stylogiannis, Parastoo Afshari, Tobias Wiedemann, Katja Steiger, Andreas Buehler, Christian Zakian, Vasilis Ntziachristos
Capsule optoacoustic endoscopy for esophageal imaging
published pages: , ISSN: 1864-063X, DOI: 10.1002/jbio.201800439
Journal of Biophotonics 12/10 2020-04-08
2020 Pierre-Marc Dansette, Raimundas Burokas, Laurynas Veselis, Audrius Zaukevičius, Andrejus Michailovas, Nerijus Rusteika
Peculiarities of second harmonic generation with chirped femtosecond pulses at high conversion efficiency
published pages: 124462, ISSN: 0030-4018, DOI: 10.1016/j.optcom.2019.124462
Optics Communications 455 2020-04-08
2019 R. A. Leitgeb
En face optical coherence tomography: a technology review [Invited]
published pages: 2177, ISSN: 2156-7085, DOI: 10.1364/BOE.10.002177
Biomedical Optics Express 10/5 2020-04-08
2019 Daniela Bovenkamp, Alexander Micko, Jeremias Püls, Fabian Placzek, Romana Höftberger, Greisa Vila, Rainer Leitgeb, Wolfgang Drexler, Marco Andreana, Stefan Wolfsberger, Angelika Unterhuber
Line Scan Raman Microspectroscopy for Label-Free Diagnosis of Human Pituitary Biopsies
published pages: 3577, ISSN: 1420-3049, DOI: 10.3390/molecules24193577
Molecules 24/19 2020-04-08
2019 Roger Fonollà, Thom Scheeve, Maarten R. Struyvenberg, Wouter L. Curvers, Albert J. de Groof, Fons van der Sommen, Erik J. Schoon, Jacques J.G.H.M. Bergman, Peter H.N. de With
Ensemble of Deep Convolutional Neural Networks for Classification of Early Barrett’s Neoplasia Using Volumetric Laser Endomicroscopy
published pages: 2183, ISSN: 2076-3417, DOI: 10.3390/app9112183
Applied Sciences 9/11 2020-04-08
2016 Lars Kirsten, Simon Baumgärtner, Mikael Timo Erkkilä, Jonas Golde, Max Kemper, Thomas Stoppe, Matthias Bornitz, Marcus Neudert, Thomas Zahnert, Edmund Koch
Doppler optical coherence tomography as a promising tool for detecting fluid in the human middle ear
published pages: , ISSN: 2364-5504, DOI: 10.1515/cdbme-2016-0098
Current Directions in Biomedical Engineering 2/1 2020-04-08
2017 Lars Kirsten, Joseph Morgenstern, Mikael Timo Erkkilä, Martin Schindler, Jonas Golde, Julia Walther, Max Kemper, Thomas Stoppe, Matthias Bornitz, Marcus Neudert, Thomas Zahnert, Edmund Koch
Functional and morphological imaging of the human tympanic membrane with endoscopic optical coherence tomography
published pages: , ISSN: 2364-5504, DOI: 10.1515/cdbme-2017-0021
Current Directions in Biomedical Engineering 3/2 2020-04-08
2019 R. A. Leitgeb
En face optical coherence tomography: a technology review [Invited]
published pages: 2177, ISSN: 2156-7085, DOI: 10.1364/boe.10.002177
Biomedical Optics Express 10/5 2020-04-08
2019 Lars Kirsten, Martin Schindler, Joseph Morgenstern, Mikael Timo Erkkilä, Jonas Golde, Julia Walther, Pascal Rottmann, Max Kemper, Matthias Bornitz, Marcus Neudert, Thomas Zahnert, Edmund Koch
Endoscopic optical coherence tomography with wide field-of-view for the morphological and functional assessment of the human tympanic membrane
published pages: 1, ISSN: 1083-3668, DOI: 10.1117/1.JBO.24.3.031017
Journal of Biomedical Optics 24/03 2020-04-08
2018 Daniela Bovenkamp, Ryan Sentosa, Elisabet Rank, Mikael Erkkilä, Fabian Placzek, Jeremias Püls, Wolfgang Drexler, Rainer Leitgeb, Nathalie Garstka, Shahrokh Shariat, Clara Stiebing, Iwan Schie, Jürgen Popp, Marco Andreana, Angelika Unterhuber
Combination of High-Resolution Optical Coherence Tomography and Raman Spectroscopy for Improved Staging and Grading in Bladder Cancer
published pages: 2371, ISSN: 2076-3417, DOI: 10.3390/app8122371
Applied Sciences 8/12 2020-04-08
2018 Roger Fonolla Navarro, Fons Van Der Sommen, Peter H N De With, Ramon M Schreuder, Erik J Schoon
Polyp malignancy classification with CNN features based on Blue Laser and Linked Color Imaging
published pages: , ISSN: , DOI:
Proceedings of NCCV2018 2020-04-08
2018 Martin Schindler, Lars Kirsten, Joseph Morgenstern, Jonas Golde, Mikael Erkkilä, Julia Walther, Max Kemper, Matthias Bornitz, Marcus Neudert, Thomas Zahnert, Edmund Koch
Imaging of the human tympanic membrane by endoscopic optical coherence tomography
published pages: 305-308, ISSN: 2364-5504, DOI: 10.1515/cdbme-2018-0074
Current Directions in Biomedical Engineering 4/1 2020-04-08
2018 Orly B. Tarun, Maksim Yu Eremchev, Sylvie Roke
Interaction of Oil and Lipids in Freestanding Lipid Bilayer Membranes Studied with Label-Free High-Throughput Wide-Field Second-Harmonic Microscopy
published pages: 11305-11310, ISSN: 0743-7463, DOI: 10.1021/acs.langmuir.8b01790
Langmuir 34/38 2020-04-08
2019 Lara M. Wurster, Ronak N. Shah, Fabian Placzek, Simon Kretschmer, Michael Niederleithner, Laurin Ginner, Jason Ensher, Michael P. Minneman, Erich E. Hoover, Hans Zappe, Wolfgang Drexler, Rainer A. Leitgeb, Çağlar Ataman
Endoscopic optical coherence tomography angiography using a forward imaging piezo scanner probe
published pages: e201800382, ISSN: 1864-063X, DOI: 10.1002/jbio.201800382
Journal of Biophotonics 2019-01-16 2020-04-08
2019 Mikael T. Erkkilä, Bianca Bauer, Nancy Hecker-Denschlag, Maria J. Madera Medina, Rainer A. Leitgeb, Angelika Unterhuber, Johanna Gesperger, Thomas Roetzer, Christoph Hauger, Wolfgang Drexler, Georg Widhalm, Marco Andreana
Widefield fluorescence lifetime imaging of protoporphyrin IX for fluorescence-guided neurosurgery: an ex vivo feasibility study
published pages: , ISSN: 1864-063X, DOI: 10.1002/jbio.201800378
Journal of Biophotonics 2020-04-08
2019 P. Albrodt, M. T. Jamal, A. K. Hansen, O. B. Jensen, G. Blume, K. Paschke, P. Crump, P. Georges, G. Lucas-Leclin
Coherent combining of high brightness tapered amplifiers for efficient non-linear conversion
published pages: 928, ISSN: 1094-4087, DOI: 10.1364/oe.27.000928
Optics Express 27/2 2020-04-08
2017 Carlos Macias-Romero, Igor Nahalka, Halil I. Okur, Sylvie Roke
Optical imaging of surface chemistry and dynamics in confinement
published pages: 784-788, ISSN: 0036-8075, DOI: 10.1126/science.aal4346
Science 357/6353 2020-04-08

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