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SOLUS SIGNED

Smart optical and ultrasound diagnostics of breast cancer

Total Cost €

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EC-Contrib. €

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Partnership

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 SOLUS project word cloud

Explore the words cloud of the SOLUS project. It provides you a very rough idea of what is the project "SOLUS" about.

chain    detectors    time    components    photonics    innovation    characterization    unmet    pulsed    care    first    female    quality    disciplinary    involvement    diffuse    picosecond    validating    54    huge    combining    academic    optical    specificity    collagen    needless    cutting    contribution    reducing    mortality    ultrasounds    push    shear    sources    tissue    levels    imaging    previously    blood    point    unthinkable    sensitivity    leadership    expertise    detector    unprecedented    small    significantly    dynamic    morphologic    source    domain    mechanical    cancer    trans    penetration    water    invasive    photons    optics    operate    elastography    cumulative    single    additional    wave    distance    countries    tomography    lipids    radiologists    engineers    miniaturized    composition    clinically    screening    innovative    life    millions    physicists    players    biophotonics    industrial    healthcare    market    mammographic    60    representing    risk    edge    laser    health    modal    savings    functional    quantitative    women    parametric    positive    breast    solus    biopsy    false    gated    industries    techniques    diagnosis    societal    stiffness    clinical   

Project "SOLUS" data sheet

The following table provides information about the project.

Coordinator
POLITECNICO DI MILANO 

Organization address
address: PIAZZA LEONARDO DA VINCI 32
city: MILANO
postcode: 20133
website: www.polimi.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website http://www.solus-project.eu
 Total cost 3˙815˙260 €
 EC max contribution 3˙815˙260 € (100%)
 Programme 1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
 Code Call H2020-ICT-2016-1
 Funding Scheme RIA
 Starting year 2016
 Duration (year-month-day) from 2016-11-01   to  2021-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    POLITECNICO DI MILANO IT (MILANO) coordinator 726˙988.00
2    VERMON SA FR (TOURS) participant 555˙312.00
3    COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES FR (PARIS 15) participant 518˙783.00
4    SUPERSONIC IMAGINE FR (AIX EN PROVENCE) participant 407˙500.00
5    MICRO PHOTON DEVICES S.R.L. IT (BOLZANO) participant 400˙711.00
6    EIBIR GEMEINNUTZIGE GMBH ZUR FORDERUNG DER ERFORSCHUNG DER BIOMEDIZINISCHEN BILDGEBUNG AT (WIEN) participant 366˙250.00
7    IC-HAUS GMBH DE (BODENHEIM) participant 327˙000.00
8    UNIVERSITY COLLEGE LONDON UK (LONDON) participant 300˙213.00
9    OSPEDALE SAN RAFFAELE SRL IT (MILANO) participant 212˙500.00

Map

 Project objective

SOLUS is a trans-disciplinary 54-month project bringing together 9 partners: industries (4), academic and clinical institutions from 5 countries (engineers, physicists and radiologists) representing cutting-edge expertise in their fields, to develop an innovative non-invasive, point-of-care, low-cost, easy-to-operate, multi-modal imaging system (diffuse optics and ultrasounds/shear wave elastography) for high-specificity diagnosis of breast cancer, the most common female cancer in Europe. Mammographic screening is effective in reducing mortality, however the 10-year cumulative false-positive risk is 50-60%, leading to needless additional invasive procedures (e.g. biopsy). The project addresses the unmet clinical need for higher specificity in breast cancer imaging following screening by fully combining photonics with non-photonics techniques, developing and clinically validating innovative and previously unthinkable photonics concepts and components: time-domain small source-detector distance optical tomography, miniaturized picosecond pulsed laser sources, high-dynamic-range time-gated single-photons detectors to achieve unprecedented sensitivity and depth penetration. For the first time, this allows a comprehensive quantitative characterization of breast tissue including composition (water, lipids, collagen), functional blood parameters, morphologic information and mechanical parameters (stiffness). This innovative multi-parametric characterization will significantly improve the specificity of breast screening, with great impact on the quality of life of millions of European women every year, and huge savings for the healthcare systems. The strong involvement of leading industrial players at all levels in the value chain will push the European innovation process and make a significant contribution to ensuring Europe’s industrial leadership in the biophotonics healthcare market, while addressing one of the largest societal challenges in health and well-being.

 Deliverables

List of deliverables.
Performances assessment of optode components Documents, reports 2020-03-24 10:48:46
Performance assessment of the single optode Documents, reports 2020-03-24 10:49:22
Updated Data Management Plan Open Research Data Pilot 2020-03-24 10:49:24
First release of the Data Management Plan Open Research Data Pilot 2020-02-27 11:35:14
Definition of paradigms representing exemplary breast lesions cases Documents, reports 2020-02-27 11:35:14
Design of multi-modal phantoms for DOT-US Documents, reports 2020-02-27 11:35:15
Definition of protocols for system characterization Documents, reports 2020-02-27 11:35:15
Definition of procedures for routine tests Documents, reports 2020-02-27 11:35:15
Visual identity and online presence Documents, reports 2020-02-27 11:35:14

Take a look to the deliverables list in detail:  detailed list of SOLUS deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Edoardo Ferocino, Antonio Pifferi, Simon Arridge, Fabrizio Martelli, Paola Taroni, Andrea Farina
Multi Simulation Platform for Time Domain Diffuse Optical Tomography: An Application to a Compact Hand-Held Reflectance Probe
published pages: 2849, ISSN: 2076-3417, DOI: 10.3390/app9142849
Applied Sciences 9/14 2020-02-27
2018 Anurag Behera, Laura Di Sieno, Antonio Pifferi, Fabrizio Martelli, Alberto Dalla Mora
Instrumental, optical and geometrical parameters affecting time-gated diffuse optical measurements: a systematic study
published pages: 5524, ISSN: 2156-7085, DOI: 10.1364/boe.9.005524
Biomedical Optics Express 9/11 2020-02-27
2019 Laura Di Sieno, Davide Contini, Giuseppe Lo Presti, Lorenzo Cortese, Tony Mateo, Bogdan Rosinski, Elena Venturini, Pietro Panizza, Mireia Mora, Gloria Aranda, Mattia Squarcia, Andrea Farina, Turgut Durduran, Paola Taroni, Antonio Pifferi, Alberto Dalla Mora
Systematic study of the effect of ultrasound gel on the performances of time-domain diffuse optics and diffuse correlation spectroscopy
published pages: 3899, ISSN: 2156-7085, DOI: 10.1364/boe.10.003899
Biomedical Optics Express 10/8 2020-02-27
2017 Edoardo Ferocino, Edoardo Martinenghi, Alberto Dalla Mora, Antonio Pifferi, Rinaldo Cubeddu, Paola Taroni
Attractive new technologies for 7-wavelength time domain optical mammography
published pages: 1041202, ISSN: , DOI: 10.1117/12.2286058
Diffuse Optical Spectroscopy and Imaging VI 2020-02-27
2017 Alberto Tosi, Mirko Sanzaro, Mauro Buttafava, Alessandro Ruggeri, Enrico Conca, Marco Renna, Federica Villa, Franco Zappa
Gating techniques for InGaAs/InP and silicon SPADs
published pages: 177, ISSN: , DOI:
Single Photon Workshop 2017 2020-02-27
2016 Laura Di Sieno, Judy Zouaoui, Lionel Hervé, Antonio Pifferi, Andrea Farina, Edoardo Martinenghi, Jacques Derouard, Jean-Marc Dinten, Alberto Dalla Mora
Time-domain diffuse optical tomography using silicon photomultipliers: feasibility study
published pages: 116002, ISSN: 1083-3668, DOI: 10.1117/1.JBO.21.11.116002
Journal of Biomedical Optics 21/11 2020-02-27
2017 Judy Zouaoui, Laura Di Sieno, Lionel Hervé, Antonio Pifferi, Andrea Farina, Alberto Dalla Mora, Jacques Derouard, Jean-Marc Dinten
Chromophore decomposition in multispectral time-resolved diffuse optical tomography
published pages: 4772, ISSN: 2156-7085, DOI: 10.1364/BOE.8.004772
Biomedical Optics Express 8/10 2020-02-27
2018 Edoardo Ferocino, Edoardo Martinenghi, Alberto Dalla Mora, Antonio Pifferi, Rinaldo Cubeddu, Paola Taroni
High throughput detection chain for time domain optical mammography
published pages: 755, ISSN: 2156-7085, DOI: 10.1364/boe.9.000755
Biomedical Optics Express 9/2 2020-02-27
2017 Paola Taroni, Anna Maria Paganoni, Francesca Ieva, Antonio Pifferi, Giovanna Quarto, Francesca Abbate, Enrico Cassano, Rinaldo Cubeddu
Non-invasive optical estimate of tissue composition to differentiate malignant from benign breast lesions: A pilot study
published pages: 40683, ISSN: 2045-2322, DOI: 10.1038/srep40683
Scientific Reports 7 2020-02-27

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