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mtFOIE GRAS SIGNED

mitoFOIE GRAS: Non-invasive Profiling of Mitochondrial Function in Non-Alcoholic Fatty Liver Disease

Total Cost €

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EC-Contrib. €

0

Partnership

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 mtFOIE GRAS project word cloud

Explore the words cloud of the mtFOIE GRAS project. It provides you a very rough idea of what is the project "mtFOIE GRAS" about.

nash    team    fatty    stages    clinical    nafld    mtfoie    disease    intersectoral    liver    gras    invasive    alcoholic   

Project "mtFOIE GRAS" data sheet

The following table provides information about the project.

Coordinator
CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO 

Organization address
address: UNIVERSIDADE DE COIMBRA, LARGO DE POMBAL
city: COIMBRA
postcode: 3004 517
website: www.cnbc.pt

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Portugal [PT]
 Total cost 454˙500 €
 EC max contribution 454˙500 € (100%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2016
 Funding Scheme /MSCA-RISE
 Starting year 2017
 Duration (year-month-day) from 2017-06-01   to  2021-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO PT (COIMBRA) coordinator 94˙500.00
2    ASSOCIACAO PROTECTORA DOS DIABETICOS DE PORTUGAL PT (LISBOA) participant 63˙000.00
3    UNIVERSITA DEGLI STUDI DI BARI ALDO MORO IT (BARI) participant 54˙000.00
4    CONSIGLIO NAZIONALE DELLE RICERCHE IT (ROMA) participant 49˙500.00
5    KING'S COLLEGE LONDON UK (LONDON) participant 40˙500.00
6    MEDIAGNOST GESELLSCHAFT FUR FORSCHUNG UND HERSTELLUNG VON DIAGNOSTIKA GMBH DE (REUTLINGEN) participant 40˙500.00
7    UNIVERSIDADE DO PORTO PT (PORTO) participant 36˙000.00
8    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) participant 13˙500.00
9    Faculdade de Farmácia da Universidade de Lisboa PT (Lisboa) participant 13˙500.00
10    HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH DE (NEUHERBERG) participant 13˙500.00
11    INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK PL (WARSZAWA) participant 13˙500.00
12    OROBOROS INSTRUMENTS GmbH AT (INNSBRUCK) participant 13˙500.00
13    MICRO-BIOLYTICS GMBH DE (ESSLINGEN AM NECKAR) participant 9˙000.00

Mappa

 Project objective

'Non-Alcoholic Fatty Liver Disease (NAFLD), including its more pathologic consequence, non-alcoholic steatohepatitis (NASH), is believed to be the most common chronic liver disease worldwide, affecting between 6 to 37% of the population. NAFLD is a so called ‘silent killer’, as clinical symptoms only surface at late stages of the disease, when it is no longer treatable: untreated, NAFLD/NASH can lead to cirrhosis and hepatocellular carcinoma, culminating in liver failure. Currently the best method of diagnosing and staging the disease is liver biopsy, a costly, invasive and somewhat risky procedure, not to mention unfit for routine assessment. Besides, no therapeutic consensus exists for NAFLD/NASH treatment. mtFOIE GRAS (Foie Gras being French for 'fat liver') proposes to address the pressing need for non-invasive, accurate, rapid assessment of NAFLD/NASH stages, before and after intervention, through the development of biomarkers and innovative tools to follow mitochondrial (mt) dysfunction, a central mediator of fatty liver disease pathogenesis. This promising R&D strategy will also bring new knowledge about the disease mechanisms and improved understanding of the pathogenic process and disease drivers. To that end, mtFOIE GRAS envisages a training-through-work plan that brings together an intersectoral, multidisciplinary team of researchers and technicians experts in their fields, from basic to translational research, clinical practice, technology commercialization and public advocacy. Together with several PhD students, the team will share expertises and work synergistically along the value creation chain to address the unmet medical need of more informative NAFLD assessment. In the process, mtFOIE GRAS will endow the involved staff with excellent scientific knowledge and transferable skills while building and strengthening intersectoral cooperation among partners, thus contributing to EU RD&I excellence.'

 Work performed, outcomes and results:  advancements report(s) 

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The information about "MTFOIE GRAS" are provided by the European Opendata Portal: CORDIS opendata.

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