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theEoE

A novel drug candidate for the treatment of Eosinophilic Esophagitis - an innovative solution for a significant unmet medical need

Total Cost €

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EC-Contrib. €

0

Partnership

0

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 theEoE project word cloud

Explore the words cloud of the theEoE project. It provides you a very rough idea of what is the project "theEoE" about.

decision    fewer    efficacy    eosinophilic    therapy    28    pain    tissue    nausea    modulating    persistent    prioritized    sustainable    eosinophils    manufacturing    toxicology    investing    modifies    generating    thelitetm    wellbeing    approved    patients    swallowing    allergens    esophagitis    regurgitation    discovery    persists    foods    fits    reduces    environmental    technologies    line    progression    proprietary    applies    company    cure    offers    white    revolutionary    uncontrolled    necessarily    revenue    topical    perfectly    embryo    causing    complications    treatment    smarter    integrity    disease    fly    inflammatory    points    cellular    europe2020    injury    promotion    payers    blood    symptoms    thanks    innovation    clinical    vomiting    lower    elicited    difficulty    barriers    risk    occurs    compounds    candidate    patented    esophagus    cell    benefit    indications    local    pathologies    healthier    inflammation    polarity    thelial    possibly    remodeling    theeoe    series    diseases    first    bioavailability    drug    accumulate    eoe    ip    health    physicians    cells    spending    time    epithelial    platform    modulation    people   

Project "theEoE" data sheet

The following table provides information about the project.

Coordinator
THELIAL TECHNOLOGIES SA 

Organization address
address: PARQUE TECNOLOGICO DE CANTANHEDE, NUCLEO 4, LOTE 3
city: CANTANHEDE
postcode: 3060197
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Portugal [PT]
 Project website http://www.thelial.com
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2016
 Duration (year-month-day) from 2016-12-01   to  2017-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THELIAL TECHNOLOGIES SA PT (CANTANHEDE) coordinator 50˙000.00

Map

 Project objective

Thelial Technologies, S.A. is a revenue generating drug discovery company that applies its unique, proprietary fly embryo-based technology to find new candidate compounds for the treatment of diseases that can be addressed by cell polarity modulation. By modulating cell polarity it is possible to specifically target a series of indications, where reduced integrity of epithelial cellular barriers is a key to pathologies. Using Thelial’s patented discovery platform theLiTETM the company has identified 28 candidate compounds, of which one – theEoE has been prioritized for further development based on toxicology, efficacy, bioavailability, IP and manufacturing decision points. theEoE will be the first approved product for treatment of Eosinophilic Esophagitis (EoE). EoE is an inflammatory disease of the esophagus elicited by foods and possibly environmental allergens. It occurs when a type of white blood cells, eosinophils, accumulate in the esophagus and persists, causing local injury and inflammation. Currently, there are no specific cure for the EoE, causing patients’ reduced wellbeing due to uncontrolled and persistent symptoms (e.g. high difficulty in swallowing, pain, nausea, regurgitation, and vomiting). Thelial offers a targeted topical treatment that reduces the clinical symptoms, modifies disease progression through tissue remodeling, and increases the duration of treatment response. These features will allow physicians, patients and payers to benefit from a revolutionary new treatment with fewer side-effects, and lower risk of health complications thanks to a better management of the disease over time. By promoting a first in line targeted therapy for EoE, Thelial’s innovation project perfectly fits the “Europe2020 challenges – for a healthier EU” 1) spending smarter but not necessarily more in sustainable health systems and 2) investing in people’s health, particularly through health-promotion programmes.

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The information about "THEEOE" are provided by the European Opendata Portal: CORDIS opendata.

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