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ELITE

Exploring LIfestyle Transitions: a molecular and physical anthropology approach of ancient Yakut people

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 ELITE project word cloud

Explore the words cloud of the ELITE project. It provides you a very rough idea of what is the project "ELITE" about.

training    century    yakut    expertise    place    fitted    latest    biodiversity    russians    genetic    genomic    susceptible    throughput    sequencing    dna    genomicist    exposed    epigenomics    lifestyle    gain    impacts    17th    world    ing    reconstructed    metagenomics    genomes    microbiomes    epigenomes    mature    fitness    diseases    health    whereby    epidemiological    driving    molecular    maladaptation    facilities    influence    physical    excellent    elite    international    ancient    massive    innovative    benefit    populations    synergy    diversity    profound    anthropo    yakuts    independent    relative    outbreaks    diet    scans    adaptation    biology    siberia    act    material    trained    acquiring    eastern    contact    interface    ideal    cultural    pressures    reveal    history    researcher    host    modern    evolutionary    organisms    selective    shifts    biological    experimental    people    proposes    reconstructing    skills    genome    environment    phenotype    combining    transition    natural    undergone    genomics    collection    multidisciplinary    context    anthropology   

Project "ELITE" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITE PAUL SABATIER TOULOUSE III 

Organization address
address: ROUTE DE NARBONNE 118
city: TOULOUSE CEDEX 9
postcode: 31062
website: www.ups-tlse.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Project website http://amis.cnrs.fr/
 Total cost 173˙076 €
 EC max contribution 173˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-09-04   to  2019-09-03

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITE PAUL SABATIER TOULOUSE III FR (TOULOUSE CEDEX 9) coordinator 173˙076.00

Map

 Project objective

Adaptation, whereby organisms become fitted to their environment, is a key evolutionary process driving biodiversity. Our understanding of how natural selection impacts genetic diversity has greatly advanced with recent developments in high-throughput DNA sequencing and genome-wide selection scans. However, microbiomes and epigenomes are other systems selection can act upon as they influence our health and phenotype, and thus our fitness. Although microbiomes, epigenomes and genomes can now be reconstructed, no study has evaluated their relative importance in populations exposed to new selective pressures. This is what ELITE aims at achieving by reconstructing the history of the biological changes undergone by the Yakut people of Far Eastern Siberia after their contact with Russians in the 17th century, and the resulting profound lifestyle transition, diet shifts and massive epidemiological outbreaks. By applying a multidisciplinary approach combining the latest advances in physical anthropology, ancient genomics, metagenomics and epigenomics to a unique collection of cultural and biological material from ancient Yakuts, ELITE proposes an innovative experimental approach in evolutionary biology, which could eventually reveal a possible maladaptation to our modern lifestyle, making us more susceptible to diseases. The success of ELITE will be based on the excellent synergy between the experienced researcher and the host institution, as the applicant will benefit from state-of-the-art facilities and expertise to gain advanced training in physical anthropology methods, while applying her genomic skills to a sample set available at no other research institution in the world. By acquiring these new skills in an international context, the experienced researcher will become a fully trained evolutionary anthropo-genomicist at the interface of physical and molecular anthropology, which will place her in ideal conditions to develop as a mature and independent researcher.

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The information about "ELITE" are provided by the European Opendata Portal: CORDIS opendata.

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