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ELITE

Exploring LIfestyle Transitions: a molecular and physical anthropology approach of ancient Yakut people

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 ELITE project word cloud

Explore the words cloud of the ELITE project. It provides you a very rough idea of what is the project "ELITE" about.

biological    host    place    diseases    century    context    history    eastern    dna    evolutionary    facilities    reveal    gain    training    people    anthropo    proposes    multidisciplinary    epidemiological    pressures    transition    natural    undergone    contact    molecular    ancient    ing    selective    russians    skills    shifts    populations    throughput    biology    ideal    elite    profound    reconstructed    expertise    experimental    phenotype    material    fitness    researcher    trained    17th    genomics    independent    excellent    metagenomics    combining    biodiversity    genetic    cultural    interface    scans    relative    anthropology    genomes    yakuts    reconstructing    outbreaks    lifestyle    synergy    mature    exposed    diversity    impacts    latest    epigenomes    benefit    driving    massive    act    acquiring    sequencing    influence    international    maladaptation    environment    epigenomics    collection    microbiomes    siberia    genome    genomicist    world    fitted    diet    organisms    genomic    modern    adaptation    health    susceptible    innovative    whereby    physical    yakut   

Project "ELITE" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITE PAUL SABATIER TOULOUSE III 

Organization address
address: ROUTE DE NARBONNE 118
city: TOULOUSE CEDEX 9
postcode: 31062
website: www.ups-tlse.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Project website http://amis.cnrs.fr/
 Total cost 173˙076 €
 EC max contribution 173˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-09-04   to  2019-09-03

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITE PAUL SABATIER TOULOUSE III FR (TOULOUSE CEDEX 9) coordinator 173˙076.00

Map

 Project objective

Adaptation, whereby organisms become fitted to their environment, is a key evolutionary process driving biodiversity. Our understanding of how natural selection impacts genetic diversity has greatly advanced with recent developments in high-throughput DNA sequencing and genome-wide selection scans. However, microbiomes and epigenomes are other systems selection can act upon as they influence our health and phenotype, and thus our fitness. Although microbiomes, epigenomes and genomes can now be reconstructed, no study has evaluated their relative importance in populations exposed to new selective pressures. This is what ELITE aims at achieving by reconstructing the history of the biological changes undergone by the Yakut people of Far Eastern Siberia after their contact with Russians in the 17th century, and the resulting profound lifestyle transition, diet shifts and massive epidemiological outbreaks. By applying a multidisciplinary approach combining the latest advances in physical anthropology, ancient genomics, metagenomics and epigenomics to a unique collection of cultural and biological material from ancient Yakuts, ELITE proposes an innovative experimental approach in evolutionary biology, which could eventually reveal a possible maladaptation to our modern lifestyle, making us more susceptible to diseases. The success of ELITE will be based on the excellent synergy between the experienced researcher and the host institution, as the applicant will benefit from state-of-the-art facilities and expertise to gain advanced training in physical anthropology methods, while applying her genomic skills to a sample set available at no other research institution in the world. By acquiring these new skills in an international context, the experienced researcher will become a fully trained evolutionary anthropo-genomicist at the interface of physical and molecular anthropology, which will place her in ideal conditions to develop as a mature and independent researcher.

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The information about "ELITE" are provided by the European Opendata Portal: CORDIS opendata.

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