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ELITE

Exploring LIfestyle Transitions: a molecular and physical anthropology approach of ancient Yakut people

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 ELITE project word cloud

Explore the words cloud of the ELITE project. It provides you a very rough idea of what is the project "ELITE" about.

people    diet    epidemiological    profound    russians    fitted    century    reveal    natural    outbreaks    eastern    whereby    interface    driving    gain    genetic    trained    excellent    mature    acquiring    fitness    dna    act    diversity    susceptible    health    organisms    exposed    world    elite    transition    independent    history    ideal    biodiversity    epigenomics    combining    cultural    genomic    yakut    populations    adaptation    diseases    siberia    proposes    genomes    ancient    relative    biology    17th    benefit    experimental    context    epigenomes    selective    environment    evolutionary    material    shifts    anthropo    host    expertise    multidisciplinary    physical    contact    massive    yakuts    international    genome    anthropology    ing    scans    skills    genomicist    sequencing    facilities    metagenomics    phenotype    collection    impacts    synergy    reconstructing    lifestyle    influence    pressures    genomics    innovative    undergone    biological    molecular    reconstructed    microbiomes    maladaptation    training    modern    latest    researcher    throughput    place   

Project "ELITE" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITE PAUL SABATIER TOULOUSE III 

Organization address
address: ROUTE DE NARBONNE 118
city: TOULOUSE CEDEX 9
postcode: 31062
website: www.ups-tlse.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Project website http://amis.cnrs.fr/
 Total cost 173˙076 €
 EC max contribution 173˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-09-04   to  2019-09-03

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITE PAUL SABATIER TOULOUSE III FR (TOULOUSE CEDEX 9) coordinator 173˙076.00

Map

 Project objective

Adaptation, whereby organisms become fitted to their environment, is a key evolutionary process driving biodiversity. Our understanding of how natural selection impacts genetic diversity has greatly advanced with recent developments in high-throughput DNA sequencing and genome-wide selection scans. However, microbiomes and epigenomes are other systems selection can act upon as they influence our health and phenotype, and thus our fitness. Although microbiomes, epigenomes and genomes can now be reconstructed, no study has evaluated their relative importance in populations exposed to new selective pressures. This is what ELITE aims at achieving by reconstructing the history of the biological changes undergone by the Yakut people of Far Eastern Siberia after their contact with Russians in the 17th century, and the resulting profound lifestyle transition, diet shifts and massive epidemiological outbreaks. By applying a multidisciplinary approach combining the latest advances in physical anthropology, ancient genomics, metagenomics and epigenomics to a unique collection of cultural and biological material from ancient Yakuts, ELITE proposes an innovative experimental approach in evolutionary biology, which could eventually reveal a possible maladaptation to our modern lifestyle, making us more susceptible to diseases. The success of ELITE will be based on the excellent synergy between the experienced researcher and the host institution, as the applicant will benefit from state-of-the-art facilities and expertise to gain advanced training in physical anthropology methods, while applying her genomic skills to a sample set available at no other research institution in the world. By acquiring these new skills in an international context, the experienced researcher will become a fully trained evolutionary anthropo-genomicist at the interface of physical and molecular anthropology, which will place her in ideal conditions to develop as a mature and independent researcher.

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The information about "ELITE" are provided by the European Opendata Portal: CORDIS opendata.

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