Opendata, web and dolomites

LearnAnx_CircAmyg SIGNED

Learning and Anxiety in Amygdala-based Neural Circuits

Total Cost €


EC-Contrib. €






 LearnAnx_CircAmyg project word cloud

Explore the words cloud of the LearnAnx_CircAmyg project. It provides you a very rough idea of what is the project "LearnAnx_CircAmyg" about.

lab    contact    conditioning    elaborated    tone    form    post    enabled    dangerous    tradeoff    gained    deep    logical    exploration    rodents    record    examine    off    protocols    embarked    rule    stimulation    environments    unveil    primates    supplemented    expanded    connectivity    made    behaviours    underlying    maladaptive    extinction    exploring    physiological    insights    evolutionary    models    circuits    medial    neurons    acquisition    generalization    disorders    suggest    translation    primate    context    human    edge    posit    behavioural    circuit    adaptive    learned    complex    aversive    cortex    cutting    major    functional    computations    prefrontal    stimuli    extinguish    basic    pfc    safe    associative    stress    mainly    mechanisms    dozens    repertoire    shock    neural    venues    pioneering    powerful    emotional    learning    trade    underlie    majority    codes    discriminate    amygdala    simultaneously    shed    animal    light    circuitry    mal    arrays    anxiety    traumatic    techniques   

Project "LearnAnx_CircAmyg" data sheet

The following table provides information about the project.


Organization address
address: HERZL STREET 234
postcode: 7610001

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Israel [IL]
 Total cost 2˙000˙000 €
 EC max contribution 2˙000˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2016-COG
 Funding Scheme ERC-COG
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2022-08-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    WEIZMANN INSTITUTE OF SCIENCE IL (REHOVOT) coordinator 2˙000˙000.00


 Project objective

Major advances were made in understanding circuits that underlie aversive emotional learning. The majority gained by using classical associative models, mainly tone/context-shock conditioning. Failure to extinguish the response or to discriminate from other safe stimuli (generalization), form two main animal models for human anxiety-disorders and post-traumatic-stress. These simple yet powerful approaches enabled cutting-edge techniques in rodents to unveil amygdala circuitry and its connectivity with the medial-prefrontal-cortex. Yet, we have less understanding of the mechanisms that underlie elaborated behavioural models of mal-adaptive behaviour, as well as less understanding of neural codes and computations in the evolutionary-expanded primate amygdala. Our lab recently embarked on exploring these venues by pioneering physiological studies of generalization and extinction protocols in primates. The goal of the current project is to develop behavioural models of complex learning and maladaptive behaviour, and then examine and shed light on the underlying computations in primate amygdala-PFC circuit. We design a novel rule-based learning task, and examine its acquisition, extinction, generalization and exploration-exploitation trade-off in dangerous environments. Specifically, the concepts of rule learning and exploration-exploitation tradeoff form novel insights and aspects of [mal-]adaptive behaviours, and will suggest new animal models of learned anxiety. We record dozens of neurons in the amygdala and prefrontal-cortex simultaneously using deep multi-contact arrays, supplemented by stimulation to address functional connectivity, and development of modelling approaches for the behaviour and neural codes. We posit that the development of more [complex] models is crucial and the next logical step in achieving translation of animal models of anxiety disorders, as well as in understanding basic mechanisms behind the rich repertoire of emotional behaviours.


year authors and title journal last update
List of publications.
2019 Raviv Pryluk, Yoav Kfir, Hagar Gelbard-Sagiv, Itzhak Fried, Rony Paz
A Tradeoff in the Neural Code across Regions and Species
published pages: 597-609.e18, ISSN: 0092-8674, DOI: 10.1016/j.cell.2018.12.032
Cell 176/3 2019-06-05
2018 Aryeh H. Taub, Yosef Shohat, Rony Paz
Long time-scales in primate amygdala neurons support aversive learning
published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-018-07020-4
Nature Communications 9/1 2019-06-05

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "LEARNANX_CIRCAMYG" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email ( and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "LEARNANX_CIRCAMYG" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

NanoPD_P (2020)

High throughput multiplexed trace-analyte screening for diagnostics applications

Read More  

FICOMOL (2019)

Field Control of Cold Molecular Collisions

Read More  

NeuroMag (2019)

The Neurological Basis of the Magnetic Sense

Read More