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ACETOGENS SIGNED

Acetogenic bacteria: from basic physiology via gene regulation to application in industrial biotechnology

Total Cost €

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EC-Contrib. €

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Partnership

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 ACETOGENS project word cloud

Explore the words cloud of the ACETOGENS project. It provides you a very rough idea of what is the project "ACETOGENS" about.

woodii    limited    substrate    reduce    metabolism    co2    absolute    monoxide    nearly    acetobacterium    bacteria    cellular    worldwide    commercial    bacterium    nothing    autotrophic    unravel    reliance    ethanol    gases    energy    producing    routes    nanoreactors    food    acetogenic    regulatory    broad    carbon    conflict    limit    creates    oxygen    road    biomass    edge    waste    acetate    substrates    demand    efforts    components    basic    realized    synthesis    platform    industrial    organelles    metabolise    bioreactors    supply    biologically    fermentations    hydrogen    engineering    fuels    organisms    storage    strain    lanzatech    commodities    facilities    blocks    feedstock    simultaneously    metabolic    cutting    bio    requirement    rely    biocommodities    acetogens    light    variety    model    organic    pave    inherent    fossil    technologies    hampered    gal    explore    forming    biosustainable    gas    humans    climate    regulation    fix    abundant    function    fuel    chemicals    demonstration    biofuels    nor    fermentation    found    building   

Project "ACETOGENS" data sheet

The following table provides information about the project.

Coordinator
JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN 

Organization address
address: THEODOR W ADORNO PLATZ 1
city: FRANKFURT AM MAIN
postcode: 60323
website: www.uni-frankfurt.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 2˙497˙140 €
 EC max contribution 2˙497˙140 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2016-ADG
 Funding Scheme ERC-ADG
 Starting year 2017
 Duration (year-month-day) from 2017-10-01   to  2022-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN DE (FRANKFURT AM MAIN) coordinator 2˙497˙140.00

Map

 Project objective

Demand for biofuels and other biologically derived commodities is growing worldwide as efforts increase to reduce reliance on fossil fuels and to limit climate change. Most commercial approaches rely on fermentations of organic matter with its inherent problems in producing CO2 and being in conflict with the food supply of humans. These problems are avoided if CO2 can be used as feedstock. Autotrophic organisms can fix CO2 by producing chemicals that are used as building blocks for the synthesis of cellular components (Biomass). Acetate-forming bacteria (acetogens) do neither require light nor oxygen for this and they can be used in bioreactors to reduce CO2 with hydrogen gas, carbon monoxide or an organic substrate. Gas fermentation using these bacteria has already been realized on an industrial level in two pre-commercial 100,000 gal/yr demonstration facilities to produce fuel ethanol from abundant waste gas resources (by LanzaTech). Acetogens can metabolise a wide variety of substrates that could be used for the production of biocommodities. However, their broad use to produce biofuels and platform chemicals from substrates other than gases or together with gases is hampered by our very limited knowledge about their metabolism and ability to use different substrates simultaneously. Nearly nothing is known about regulatory processes involved in substrate utilization or product formation but this is an absolute requirement for metabolic engineering approaches. The aim of this project is to provide this basic knowledge about metabolic routes in the acetogenic model strain Acetobacterium woodii and their regulation. We will unravel the function of “organelles” found in this bacterium and explore their potential as bio-nanoreactors for the production of biocommodities and pave the road for the industrial use of A. woodii in energy (hydrogen) storage. Thus, this project creates cutting-edge opportunities for the development of biosustainable technologies in Europe.

 Publications

year authors and title journal last update
List of publications.
2018 Patrick Kottenhahn, Kai Schuchmann, Volker Müller
Efficient whole cell biocatalyst for formate-based hydrogen production
published pages: , ISSN: 1754-6834, DOI: 10.1186/s13068-018-1082-3
Biotechnology for Biofuels 11/1 2019-06-07
2018 Fabian M. Schwarz, Kai Schuchmann, Volker Müller
Hydrogenation of CO2 at ambient pressure catalyzed by a highly active thermostable biocatalyst
published pages: , ISSN: 1754-6834, DOI: 10.1186/s13068-018-1236-3
Biotechnology for Biofuels 11/1 2019-06-07
2018 Kai Schuchmann, Nilanjan Pal Chowdhury, Volker Müller
Complex Multimeric [FeFe] Hydrogenases: Biochemistry, Physiology and New Opportunities for the Hydrogen Economy
published pages: , ISSN: 1664-302X, DOI: 10.3389/fmicb.2018.02911
Frontiers in Microbiology 9 2019-06-07

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The information about "ACETOGENS" are provided by the European Opendata Portal: CORDIS opendata.

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