Opendata, web and dolomites

NebuFlox

Making it happen - Scalable biphasic reactions using a nebulizer-driven continuous flow reactor

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 NebuFlox project word cloud

Explore the words cloud of the NebuFlox project. It provides you a very rough idea of what is the project "NebuFlox" about.

flow    chemicals    herein    solubility    operations    excellent    transformed    pot    proving    representing    global    exploited    readily    breakthrough    commercialization    superbly    chamber    benign    efficient    castrate    enlarging    synthesis    expert    industrial    curtailed    grant    projecting    pi    technologies    reactions    waste    amplify    realization    erc    sustainable    start    dimension    advisory    small    pharmaceutical    solutions    poor    cloud    power    seek    prospects    pursue    sought    prevailed    plant    chemical    form    act    giant    severely    made    nebulizer    reactor    automate    fine    remarkable    straightforward    seemed    extremely    latest    droplets    plan    biphasic    filled    materials    delineated    relevance    worked    astrazeneca    obvious    scales    diversity    good    team    had    fix    accessible    usefulness    structures    original    frameworks    exceptionally    light    suited    look    automation    innovative    chemistry    penetration    air    continuous    combined    pilot    oxygen    explore    prototype    mentor    excited   

Project "NebuFlox" data sheet

The following table provides information about the project.

Coordinator
PANEPISTIMIO KRITIS 

Organization address
address: UNIVERSITY CAMPUS GALLOS
city: RETHIMNO
postcode: 74100
website: www.uoc.gr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Greece [EL]
 Total cost 150˙000 €
 EC max contribution 150˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-PoC
 Funding Scheme ERC-POC
 Starting year 2018
 Duration (year-month-day) from 2018-01-01   to  2019-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    PANEPISTIMIO KRITIS EL (RETHIMNO) coordinator 150˙000.00

Map

 Project objective

The original ERC grant focused on proving the power that oxygen from the air had in synthesis when its light-excited state was exploited. During the ERC program, we were able to show how simple & readily accessible start materials could be transformed into high value-high interest chemicals through straightforward “one pot” operations. We were also able to show that the diversity of structures accessible using this chemistry is remarkable. Furthermore, it is highly sustainable; representing a very efficient, benign & extremely low waste approach to the production of sought-after chemical frameworks. However, one problem prevailed. While it worked exceptionally well on a small research scale, its overall usefulness and its industrial relevance were severely curtailed by scale-up issues, even when the latest continuous flow technologies were applied. The need to achieve good light penetration, combined with the poor solubility of oxygen, seemed to castrate the potential of this chemistry to provide global solutions. A key breakthrough was made towards the end of the ERC program with the realization that creating and projecting a cloud (using a nebulizer to make fine droplets) into a light filled chamber could solve ALL the problems and lead to large scale reactions. With the current proposal, we seek to explore and fully automate this highly innovative nebulizer process in order to develop a robust prototype reactor with excellent prospects for further dimension enlarging (to industrial pilot plant scales & beyond). Furthermore, it is obvious that this “nebulizer fix” may also be superbly suited to other biphasic reactions. Our plan has the support of pharmaceutical giant AstraZeneca in the form of an automation expert who will act as mentor to the program. The PI & the advisory team will pursue a number of different commercialization opportunities delineated herein and look at how best to exploit and amplify the impact of the extremely efficient prototype reactor(s).

 Publications

year authors and title journal last update
List of publications.
2018 Georgios I. Ioannou, Tamsyn Montagnon, Dimitris Kalaitzakis, Spiros A. Pergantis, Georgios Vassilikogiannakis
One-Pot Synthesis of Diverse γ-Lactam Scaffolds Facilitated by a Nebulizer-Based Continuous Flow Photoreactor
published pages: 860-864, ISSN: 2367-0932, DOI: 10.1002/cptc.201800068
ChemPhotoChem 2/10 2019-11-06

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "NEBUFLOX" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "NEBUFLOX" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

Aware (2019)

Aiding Antibiotic Development with Deep Analysis of Resistance Evolution

Read More  

Resonances (2019)

Resonances and Zeta Functions in Smooth Ergodic Theory and Geometry

Read More  

CARBYNE (2020)

New carbon reactivity rules for molecular editing

Read More