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PRECISE4Q SIGNED

Personalised Medicine by Predictive Modeling in Stroke for better Quality of Life

Total Cost €

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EC-Contrib. €

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Partnership

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PRECISE4Q project word cloud

Explore the words cloud of the PRECISE4Q project. It provides you a very rough idea of what is the project "PRECISE4Q" about.

simulation gender measurable predictive stages biochemical platform genomics sources guidelines coping heterogeneous reaching gathering clinicians dimensional brain socio decision first semantic reintegration data standardisation gradient mechanistic treatment outcomes retrospective time biophysiological create models computer registries severe personalised medical boosting big society insurance life multidisciplinary cdss deep strategies burden schematic sustainable social precision stage lifestyle economic architectures rehab hybrid validated rehabilitation health planning stroke prospective electronic imaging form requiring model learning cohort efforts qvidlab structured therapy risk microbiomics perfusion clinical acute optimise momentum individual substantial minimise prevention clinically prediction tool contrast digital capability public function extraction labelling resilience records precise4q patient patients journey worklife ageing

Project "PRECISE4Q" data sheet

The following table provides information about the project.

Coordinator	CHARITE - UNIVERSITAETSMEDIZIN BERLIN Organization address address: Chariteplatz 1 city: BERLIN postcode: 10117 website: www.charite.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Germany [DE]
Total cost	5˙978˙245 €
EC max contribution	5˙978˙245 € (100%)
Programme	1. H2020-EU.3.1.5. (Methods and data)
Code Call	H2020-SC1-2017-CNECT-2
Funding Scheme	RIA
Starting year	2018
Duration (year-month-day)	from 2018-05-01 to 2022-04-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	CHARITE - UNIVERSITAETSMEDIZIN BERLIN CHARITE - UNIVERSITAETSMEDIZIN BERLIN Organization address address: Chariteplatz 1 city: BERLIN postcode: 10117 website: www.charite.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BERLIN)	coordinator	1˙276˙250.00
2	TECHNOLOGICAL UNIVERSITY DUBLIN TECHNOLOGICAL UNIVERSITY DUBLIN Organization address address: NORTH CIRCULAR ROAD 191 PARK HOUSE GRANGEGORMAN city: DUBLIN postcode: D07 EWV4 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (DUBLIN)	participant	1˙005˙000.00
3	EMPIRICA GESELLSCHAFT FUR KOMMUNIKATIONS UND TECHNOLOGIEFORSCHUNG MBH EMPIRICA GESELLSCHAFT FUR KOMMUNIKATIONS UND TECHNOLOGIEFORSCHUNG MBH Organization address address: OXFORDSTRASSE 2 city: BONN postcode: 53111 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BONN)	participant	567˙750.00
4	EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH Organization address address: Raemistrasse 101 city: ZUERICH postcode: 8092 website: https://www.ethz.ch/de.html contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (ZUERICH)	participant	467˙205.00
5	LINKOPINGS UNIVERSITET LINKOPINGS UNIVERSITET Organization address address: CAMPUS VALLA city: LINKOPING postcode: 581 83 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (LINKOPING)	participant	454˙225.00
6	MEDIZINISCHE UNIVERSITAT GRAZ MEDIZINISCHE UNIVERSITAT GRAZ Organization address address: AUENBRUGGERPLATZ 2 city: GRAZ postcode: 8036 website: http://www.medunigraz.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (GRAZ)	participant	398˙125.00
7	QMENTA IMAGING, SL QMENTA IMAGING, SL Organization address address: CALLE ROGER DE LLURIA 46, PRINCIPAL 1A city: BARCELONA postcode: 8009 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BARCELONA)	participant	392˙500.00
8	FUNDACIO INSTITUT GUTTMANN FUNDACIO INSTITUT GUTTMANN Organization address address: CAMI DE CAN RUTI SN city: BADALONA postcode: 8916 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BADALONA)	participant	377˙190.00
9	TARTU ULIKOOL TARTU ULIKOOL Organization address address: ULIKOOLI 18 city: TARTU postcode: 51005 website: www.ut.ee contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EE (TARTU)	participant	366˙250.00
10	DEUTSCHES FORSCHUNGSZENTRUM FUR KUNSTLICHE INTELLIGENZ GMBH DEUTSCHES FORSCHUNGSZENTRUM FUR KUNSTLICHE INTELLIGENZ GMBH Organization address address: TRIPPSTADTER STRASSE 122 city: KAISERSLAUTERN postcode: 67663 website: www.dfki.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (KAISERSLAUTERN)	participant	281˙250.00
11	UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN Organization address address: BELFIELD city: DUBLIN postcode: 4 website: www.ucd.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (DUBLIN)	participant	273˙750.00
12	AOK NORDOST - DIE GESUNDHEITSKASSE AOK NORDOST - DIE GESUNDHEITSKASSE Organization address address: BEHLERTSTRASSE 33A city: POSTDAM postcode: 14467 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (POSTDAM)	participant	118˙750.00
13	INSTITIUID TEICNEOLAIOCHTA BHAILE ATHA CLIATH INSTITIUID TEICNEOLAIOCHTA BHAILE ATHA CLIATH Organization address address: GRANGEGORMAN LOWER city: DUBLIN postcode: D07 H6K8 website: http://www.dit.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (DUBLIN)	participant	0.00

Map

Project objective

Stroke is one of the most severe medical problems with far-reaching public health and socio-economic impact, gathering momentum in an ageing society. PRECISE4Q sets out to minimise the burden of stroke for the individual and for society. It will create multi-dimensional data-driven predictive simulation computer models enabling – for the first time – personalised stroke treatment, addressing patient’s needs in four stages: prevention, acute treatment, rehabilitation and reintegration. Heterogeneous data from multidisciplinary sources will be integrated: genomics, microbiomics, biochemical; imaging including mechanistic biophysiological models of brain perfusion/function; social, lifestyle, gender; economic and worklife, requiring substantial efforts for information extraction, semantic labelling and standardisation. Novel hybrid model architectures, structured prediction models, complex deep-learning and gradient boosting models will form the Digital Stroke Patient Platform including a Stroke Risk CDSS (Clinical Decision Support System), Treatment Outcomes CDSS, Rehab Programme, Socio-Economic Planning Tool and New QvidLab. The decision support will be tailored to the patient's current life stage thus enabling clinicians to optimise prevention and treatment strategies over time, and will include personalised coping strategies, support of well-being and reintegration into social life and work. The predictive capability and clinical precision will be validated with real clinical data generated by (i) prospective clinical studies and (ii) retrospective analyses of big data sets: health registries, cohort studies, health insurance data, electronic health records. PRECISE4Q will have a clinically measurable and sustainable impact leading to better understanding of risk, health and resilience factors. In contrast to current schematic therapy guidelines, it will support patients throughout their life-long journey by personalised strategies for their specific needs.

Deliverables

List of deliverables.
Use cases and their inputs/outputs specifications	Documents, reports	2020-04-11 08:13:20
SoA for stroke risk factors, prognosis and outcomes	Documents, reports	2020-04-11 08:13:19
Implementation of accessing and bridging functionalities	Documents, reports	2020-04-11 08:13:19
Overview of data sources and a plan to access available data sources	Documents, reports	2020-04-11 08:13:20
Written concept which is approved by the regulation authorities	Documents, reports	2020-04-11 08:13:20
QoL targets for the models created in T4.5, T4.6, T4.7, T4.8	Documents, reports	2020-04-11 08:13:20
Electronic patient recorded outcome framework (ePRO)	Documents, reports	2020-04-11 08:13:20
Study design rehabilitation/reintegration	Documents, reports	2020-04-11 08:13:20
Categorized and ranked clinical challenges and needs	Documents, reports	2020-04-11 08:13:19
White paper on hybrid model fusion strategies	Documents, reports	2020-04-11 08:13:20
Project management plan and quality assurance process guidelines	Documents, reports	2020-04-11 08:13:20
Corporate identity, branding policy, and project website	Documents, reports	2020-04-11 08:13:20
Decision of build of the data warehouse	Documents, reports	2020-04-11 08:13:20
Functional harmonization of Users, Roles and Access	Documents, reports	2020-04-11 08:13:20
Study design for stroke treatment	Documents, reports	2020-04-11 08:13:20
Communication and publication strategy	Documents, reports	2020-04-11 08:13:20
Data Schema Designs for Each Model	Documents, reports	2020-04-09 20:02:44
White paper on stroke risk, health and resilience factors	Documents, reports	2020-04-09 20:02:36

Take a look to the deliverables list in detail: detailed list of PRECISE4Q deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2018	Effy Vayena, Alessandro Blasimme, I. Glenn Cohen Machine learning in medicine: Addressing ethical challenges published pages: e1002689, ISSN: 1549-1676, DOI: 10.1371/journal.pmed.1002689	PLOS Medicine 15/11	2020-04-11
2020	Blasimme, Alessandro and Vayena, Effy The Ethics of AI in Biomedical Research, Patient Care and Public Health published pages: , ISSN: , DOI:	Oxford Handbook of Ethics of Artificial Intelligence	2020-04-11
2019	Alejandro GarcÃa-Rudolph, David SÃ¡nchez-Pinsach, Eloy Opisso Salleras, Josep MarÃa Tormos Subacute stroke physical rehabilitation evidence in activities of daily living outcomes published pages: e14501, ISSN: 0025-7974, DOI: 10.1097/md.0000000000014501	Medicine 98/8	2020-04-11
2019	Alessandro Blasimme, Effy Vayena, Ine Van Hoyweghen Big Data, precision medicine and private insurance: A delicate balancing act published pages: 205395171983011, ISSN: 2053-9517, DOI: 10.1177/2053951719830111	Big Data & Society 6/1	2020-04-11
2019	Alejandro Garcia-Rudolph, Sara Laxe, Joan SaurÃ, Montserrat Bernabeu Guitart Stroke Survivors on Twitter: Sentiment and Topic Analysis From a Gender Perspective published pages: e14077, ISSN: 1438-8871, DOI: 10.2196/14077	Journal of Medical Internet Research 21/8	2020-04-11

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