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LeiSHield-MATI SIGNED

A multi-disciplinary international effort to identify clinical, molecular and social factors impacting cutaneous leishmaniasis

Total Cost €

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EC-Contrib. €

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Partnership

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 LeiSHield-MATI project word cloud

Explore the words cloud of the LeiSHield-MATI project. It provides you a very rough idea of what is the project "LeiSHield-MATI" about.

samples    scientists    leishield    isolates    patients    public    leishmania    first    discovery    capitalizing    representing    basin    tunisia    genetic    declared    prognostic    biology    integrative    natural    drive    vector    diagnostic    regions    immunology    endemic    complementary    preventive    generating    climate    scientific    expertise    iran    computational    leishmaniasis    powerful    understand    pipeline    clinical    bioinformatics    mati    structure    human    morrocco    interplay    sectorial    generation    marker    dermatology    outcome    mediterranean    asian    displacement    interaction    courses    disease    plan    parasite    sustainability    disciplinary    infrastructures    strengthen    leishmaniases    algeria    infected    population    epidemiology    bio    countries    infection    therapeutic    self    parasitic    diseases    host    train    parasitology    animal    time    african    impacts    inform    innovation    organization    tools    devastating    ultimate    health    workshops    secondment    cutaneous    fashion    inter    commercial    causes    molecular    capacities   

Project "LeiSHield-MATI" data sheet

The following table provides information about the project.

Coordinator
INSTITUT PASTEUR 

Organization address
address: RUE DU DOCTEUR ROUX 25-28
city: PARIS CEDEX 15
postcode: 75724
website: http://www.pasteur.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
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 Coordinator Country France [FR]
 Total cost 1˙750˙500 €
 EC max contribution 1˙750˙500 € (100%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2017
 Funding Scheme MSCA-RISE
 Starting year 2018
 Duration (year-month-day) from 2018-04-01   to  2022-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUT PASTEUR FR (PARIS CEDEX 15) coordinator 526˙500.00
2    INSTITUT PASTEUR DE TUNIS TN (TUNIS) participant 783˙000.00
3    PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE BE (ANTWERPEN) participant 211˙500.00
4    GOETEBORGS UNIVERSITET SE (GOETEBORG) participant 112˙500.00
5    UNIVERZITA KARLOVA CZ (PRAHA 1) participant 94˙500.00
6    ACOBIOM FR (GRABELS) participant 22˙500.00
7    INSTITUT PASTEUR D ALGERIE E.P.I.C. DZ (ALGER) partner 0.00
8    INSTITUT PASTEUR D'IRAN IR (TEHRAN) partner 0.00
9    Institut Pasteur Du Maroc MA (Casablanca) partner 0.00

Map

 Project objective

Leishmania causes devastating human diseases – leishmaniases - representing an important public health problem in the Mediterranean basin and declared as emerging diseases in the EU due to climate change and population displacement. The LeiSHield-MATI consortium will for the first time investigate in an integrative fashion the complex parasite-vector-host interplay in cutaneous leishmaniasis affecting Morrocco, Algeria, Tunisia, and Iran (MATI), using field isolates and human clinical samples. The ultimate goal of our project is to identify genetic factors selected during natural infection and to understand how the complex parasite-vector-animal interaction impacts clinical outcome in infected patients. This goal will be achieved through a highly ambitious secondment plan between all partners, and the organization of courses and workshops to train the next generation of scientists generating a long-term impact on the research capacities in endemic areas. Capitalizing on complementary infrastructures of its EU, African and Asian partners and their expertise in molecular parasitology, epidemiology, systems level analyses, bioinformatics, computational biology, immunology, dermatology, field studies, and public health, our project will drive important innovation in clinical research, strengthen capacities in disease endemic regions, inform authorities on control measures, and raise awareness in all partner countries on this emerging EU public health problem. The highly inter-disciplinary and inter-sectorial structure of LeiSHield-MATI, and its powerful integrative and comparative approach is novel in parasitic systems and will drive a unique bio-marker discovery pipeline for the future development of new prognostic and diagnostic tools, as well as novel preventive and therapeutic measures that will ensure long-term collaboration, promote scientific and commercial self-sustainability of its partners, and will have an important impact to improve public health.

 Deliverables

List of deliverables.
Kick-off meeting, a booklet compiling project documentation provided to all partners, a web-based project management platform accessible through the LeiSHield-MATI website Other 2019-06-19 13:18:07

Take a look to the deliverables list in detail:  detailed list of LeiSHield-MATI deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Fariborz Bahrami, Sima Rafati
The LeiSHield-MATI Consortium: An International Project to Understand and Combat Cutaneous Leishmaniasis through Research and Innovation Staff Exchange
published pages: , ISSN: 2345-5349, DOI: 10.29252/jommid.7.3.85
Journal of Medical Microbiology and Infectious Diseases (JOMMID) 2019 Volume 7 Number 4 2020-03-23
2020 Yasaman Taslimia, Christopher Agbajogub, Siggeir Fannar Brynjolfssonc, Nasrin Masoudzadeha, Vahid Mashayekhid, Safoora Gharibzadehe, Malin Östenssonb, Sravya Sowdamini Nakkab, Amir Mizbanif, Sima Rafatia,⁎,1, Ali M. Harandib,g,⁎,1
Profiling inflammatory response in lesions of cutaneous leishmaniasis patients using a non-invasive sampling method combined with a high-throughput protein detection assay.
published pages: , ISSN: 1043-4666, DOI:
Cytokine 2020-03-23

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The information about "LEISHIELD-MATI" are provided by the European Opendata Portal: CORDIS opendata.

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