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LeiSHield-MATI SIGNED

A multi-disciplinary international effort to identify clinical, molecular and social factors impacting cutaneous leishmaniasis

Total Cost €

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EC-Contrib. €

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Partnership

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 LeiSHield-MATI project word cloud

Explore the words cloud of the LeiSHield-MATI project. It provides you a very rough idea of what is the project "LeiSHield-MATI" about.

algeria    endemic    infection    immunology    structure    drive    samples    time    infrastructures    prognostic    capitalizing    complementary    devastating    host    generating    innovation    sustainability    fashion    computational    human    plan    tunisia    inter    iran    molecular    bio    public    impacts    inform    infected    secondment    epidemiology    climate    self    morrocco    commercial    parasitic    powerful    african    health    regions    causes    scientists    interplay    basin    mati    bioinformatics    strengthen    vector    outcome    interaction    countries    animal    parasitology    workshops    natural    diseases    genetic    preventive    isolates    organization    discovery    parasite    disciplinary    integrative    dermatology    clinical    tools    therapeutic    biology    leishmaniases    courses    understand    leishmaniasis    displacement    diagnostic    ultimate    population    marker    cutaneous    disease    representing    expertise    pipeline    generation    leishield    mediterranean    patients    asian    first    scientific    capacities    train    leishmania    declared    sectorial   

Project "LeiSHield-MATI" data sheet

The following table provides information about the project.

Coordinator
INSTITUT PASTEUR 

Organization address
address: RUE DU DOCTEUR ROUX 25-28
city: PARIS CEDEX 15
postcode: 75724
website: http://www.pasteur.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
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 Coordinator Country France [FR]
 Total cost 1˙750˙500 €
 EC max contribution 1˙750˙500 € (100%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2017
 Funding Scheme MSCA-RISE
 Starting year 2018
 Duration (year-month-day) from 2018-04-01   to  2022-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUT PASTEUR FR (PARIS CEDEX 15) coordinator 526˙500.00
2    INSTITUT PASTEUR DE TUNIS TN (TUNIS) participant 783˙000.00
3    PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE BE (ANTWERPEN) participant 211˙500.00
4    GOETEBORGS UNIVERSITET SE (GOETEBORG) participant 112˙500.00
5    UNIVERZITA KARLOVA CZ (PRAHA 1) participant 94˙500.00
6    ACOBIOM FR (GRABELS) participant 22˙500.00
7    INSTITUT PASTEUR D ALGERIE E.P.I.C. DZ (ALGER) partner 0.00
8    INSTITUT PASTEUR D'IRAN IR (TEHRAN) partner 0.00
9    Institut Pasteur Du Maroc MA (Casablanca) partner 0.00

Map

 Project objective

Leishmania causes devastating human diseases – leishmaniases - representing an important public health problem in the Mediterranean basin and declared as emerging diseases in the EU due to climate change and population displacement. The LeiSHield-MATI consortium will for the first time investigate in an integrative fashion the complex parasite-vector-host interplay in cutaneous leishmaniasis affecting Morrocco, Algeria, Tunisia, and Iran (MATI), using field isolates and human clinical samples. The ultimate goal of our project is to identify genetic factors selected during natural infection and to understand how the complex parasite-vector-animal interaction impacts clinical outcome in infected patients. This goal will be achieved through a highly ambitious secondment plan between all partners, and the organization of courses and workshops to train the next generation of scientists generating a long-term impact on the research capacities in endemic areas. Capitalizing on complementary infrastructures of its EU, African and Asian partners and their expertise in molecular parasitology, epidemiology, systems level analyses, bioinformatics, computational biology, immunology, dermatology, field studies, and public health, our project will drive important innovation in clinical research, strengthen capacities in disease endemic regions, inform authorities on control measures, and raise awareness in all partner countries on this emerging EU public health problem. The highly inter-disciplinary and inter-sectorial structure of LeiSHield-MATI, and its powerful integrative and comparative approach is novel in parasitic systems and will drive a unique bio-marker discovery pipeline for the future development of new prognostic and diagnostic tools, as well as novel preventive and therapeutic measures that will ensure long-term collaboration, promote scientific and commercial self-sustainability of its partners, and will have an important impact to improve public health.

 Deliverables

List of deliverables.
Kick-off meeting, a booklet compiling project documentation provided to all partners, a web-based project management platform accessible through the LeiSHield-MATI website Other 2019-06-19 13:18:07

Take a look to the deliverables list in detail:  detailed list of LeiSHield-MATI deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Fariborz Bahrami, Sima Rafati
The LeiSHield-MATI Consortium: An International Project to Understand and Combat Cutaneous Leishmaniasis through Research and Innovation Staff Exchange
published pages: , ISSN: 2345-5349, DOI: 10.29252/jommid.7.3.85
Journal of Medical Microbiology and Infectious Diseases (JOMMID) 2019 Volume 7 Number 4 2020-03-23
2020 Yasaman Taslimia, Christopher Agbajogub, Siggeir Fannar Brynjolfssonc, Nasrin Masoudzadeha, Vahid Mashayekhid, Safoora Gharibzadehe, Malin Östenssonb, Sravya Sowdamini Nakkab, Amir Mizbanif, Sima Rafatia,⁎,1, Ali M. Harandib,g,⁎,1
Profiling inflammatory response in lesions of cutaneous leishmaniasis patients using a non-invasive sampling method combined with a high-throughput protein detection assay.
published pages: , ISSN: 1043-4666, DOI:
Cytokine 2020-03-23

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