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LeiSHield-MATI SIGNED

A multi-disciplinary international effort to identify clinical, molecular and social factors impacting cutaneous leishmaniasis

Total Cost €

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EC-Contrib. €

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Partnership

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LeiSHield-MATI project word cloud

Explore the words cloud of the LeiSHield-MATI project. It provides you a very rough idea of what is the project "LeiSHield-MATI" about.

disciplinary samples human outcome regions marker plan understand devastating discovery integrative structure population parasitology complementary commercial molecular capitalizing patients diagnostic african displacement tunisia mati mediterranean first capacities diseases impacts scientists declared scientific epidemiology sectorial countries prognostic self algeria innovation sustainability infrastructures generating leishmania immunology dermatology time infection tools leishmaniasis computational generation iran organization biology preventive workshops interplay leishield bio host representing parasitic leishmaniases strengthen pipeline causes disease health animal parasite interaction bioinformatics isolates vector inform clinical basin secondment drive genetic ultimate expertise courses cutaneous natural powerful train therapeutic climate endemic inter public morrocco infected fashion asian

Project "LeiSHield-MATI" data sheet

The following table provides information about the project.

Coordinator	INSTITUT PASTEUR Organization address address: RUE DU DOCTEUR ROUX 25-28 city: PARIS CEDEX 15 postcode: 75724 website: http://www.pasteur.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	France [FR]
Total cost	1˙750˙500 €
EC max contribution	1˙750˙500 € (100%)
Programme	1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
Code Call	H2020-MSCA-RISE-2017
Funding Scheme	MSCA-RISE
Starting year	2018
Duration (year-month-day)	from 2018-04-01 to 2022-03-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	INSTITUT PASTEUR INSTITUT PASTEUR Organization address address: RUE DU DOCTEUR ROUX 25-28 city: PARIS CEDEX 15 postcode: 75724 website: http://www.pasteur.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS CEDEX 15)	coordinator	526˙500.00
2	INSTITUT PASTEUR DE TUNIS INSTITUT PASTEUR DE TUNIS Organization address address: Place Pasteur 13 city: TUNIS postcode: 1002 website: www.pasteur.tn contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	TN (TUNIS)	participant	783˙000.00
3	PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE Organization address address: Nationalestraat 155 city: ANTWERPEN postcode: 2000 website: www.itg.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (ANTWERPEN)	participant	211˙500.00
4	GOETEBORGS UNIVERSITET GOETEBORGS UNIVERSITET Organization address address: VASAPARKEN city: GOETEBORG postcode: 405 30 website: www.gu.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (GOETEBORG)	participant	112˙500.00
5	UNIVERZITA KARLOVA UNIVERZITA KARLOVA Organization address address: OVOCNY TRH 560/5 city: PRAHA 1 postcode: 116 36 website: www.cuni.cz contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CZ (PRAHA 1)	participant	94˙500.00
6	ACOBIOM ACOBIOM Organization address address: 1682 RUE DE LA VALSIERE CAP DELTA ZAC EUROMEDECINE II city: GRABELS postcode: 34790 website: www.acobiom.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (GRABELS)	participant	22˙500.00
7	INSTITUT PASTEUR D ALGERIE E.P.I.C. INSTITUT PASTEUR D ALGERIE E.P.I.C. Organization address address: ROUTE DU PETIT STAOUELI DELY BRAHIM city: ALGER postcode: 16000 website: www.pasteur.dz contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DZ (ALGER)	partner	0.00
8	INSTITUT PASTEUR D'IRAN INSTITUT PASTEUR D'IRAN Organization address address: PASTEUR AVE 69 city: TEHRAN postcode: 1316943551 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IR (TEHRAN)	partner	0.00
9	Institut Pasteur Du Maroc Institut Pasteur Du Maroc Organization address address: Place Louis Pasteur 1 city: Casablanca postcode: 20360 website: www.pasteur.ma contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	MA (Casablanca)	partner	0.00

Map

Project objective

Leishmania causes devastating human diseases – leishmaniases - representing an important public health problem in the Mediterranean basin and declared as emerging diseases in the EU due to climate change and population displacement. The LeiSHield-MATI consortium will for the first time investigate in an integrative fashion the complex parasite-vector-host interplay in cutaneous leishmaniasis affecting Morrocco, Algeria, Tunisia, and Iran (MATI), using field isolates and human clinical samples. The ultimate goal of our project is to identify genetic factors selected during natural infection and to understand how the complex parasite-vector-animal interaction impacts clinical outcome in infected patients. This goal will be achieved through a highly ambitious secondment plan between all partners, and the organization of courses and workshops to train the next generation of scientists generating a long-term impact on the research capacities in endemic areas. Capitalizing on complementary infrastructures of its EU, African and Asian partners and their expertise in molecular parasitology, epidemiology, systems level analyses, bioinformatics, computational biology, immunology, dermatology, field studies, and public health, our project will drive important innovation in clinical research, strengthen capacities in disease endemic regions, inform authorities on control measures, and raise awareness in all partner countries on this emerging EU public health problem. The highly inter-disciplinary and inter-sectorial structure of LeiSHield-MATI, and its powerful integrative and comparative approach is novel in parasitic systems and will drive a unique bio-marker discovery pipeline for the future development of new prognostic and diagnostic tools, as well as novel preventive and therapeutic measures that will ensure long-term collaboration, promote scientific and commercial self-sustainability of its partners, and will have an important impact to improve public health.

Deliverables

List of deliverables.
Kick-off meeting, a booklet compiling project documentation provided to all partners, a web-based project management platform accessible through the LeiSHield-MATI website	Other	2019-06-19 13:18:07

Take a look to the deliverables list in detail: detailed list of LeiSHield-MATI deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Fariborz Bahrami, Sima Rafati The LeiSHield-MATI Consortium: An International Project to Understand and Combat Cutaneous Leishmaniasis through Research and Innovation Staff Exchange published pages: , ISSN: 2345-5349, DOI: 10.29252/jommid.7.3.85	Journal of Medical Microbiology and Infectious Diseases (JOMMID) 2019 Volume 7 Number 4	2020-03-23
2020	Yasaman Taslimia, Christopher Agbajogub, Siggeir Fannar Brynjolfssonc, Nasrin Masoudzadeha, Vahid Mashayekhid, Safoora Gharibzadehe, Malin Ã–stenssonb, Sravya Sowdamini Nakkab, Amir Mizbanif, Sima Rafatia,âŽ,1, Ali M. Harandib,g,âŽ,1 Profiling inflammatory response in lesions of cutaneous leishmaniasis patients using a non-invasive sampling method combined with a high-throughput protein detection assay. published pages: , ISSN: 1043-4666, DOI:	Cytokine	2020-03-23

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The information about "LEISHIELD-MATI" are provided by the European Opendata Portal: CORDIS opendata.

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