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LeiSHield-MATI SIGNED

A multi-disciplinary international effort to identify clinical, molecular and social factors impacting cutaneous leishmaniasis

Total Cost €

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EC-Contrib. €

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Partnership

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 LeiSHield-MATI project word cloud

Explore the words cloud of the LeiSHield-MATI project. It provides you a very rough idea of what is the project "LeiSHield-MATI" about.

tunisia    discovery    ultimate    leishmania    bio    train    countries    self    generation    sectorial    understand    courses    clinical    diseases    devastating    diagnostic    dermatology    tools    workshops    sustainability    inform    fashion    integrative    plan    infected    capacities    iran    health    mati    african    displacement    first    causes    preventive    biology    organization    prognostic    inter    mediterranean    powerful    regions    morrocco    disciplinary    parasitology    patients    representing    samples    outcome    scientists    expertise    therapeutic    infrastructures    capitalizing    algeria    interaction    natural    leishmaniasis    leishmaniases    climate    interplay    population    generating    time    computational    bioinformatics    leishield    cutaneous    parasitic    secondment    host    asian    marker    pipeline    drive    disease    genetic    epidemiology    human    complementary    infection    impacts    structure    strengthen    basin    endemic    commercial    scientific    public    animal    molecular    parasite    isolates    immunology    innovation    declared    vector   

Project "LeiSHield-MATI" data sheet

The following table provides information about the project.

Coordinator
INSTITUT PASTEUR 

Organization address
address: RUE DU DOCTEUR ROUX 25-28
city: PARIS CEDEX 15
postcode: 75724
website: http://www.pasteur.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
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 Coordinator Country France [FR]
 Total cost 1˙750˙500 €
 EC max contribution 1˙750˙500 € (100%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2017
 Funding Scheme MSCA-RISE
 Starting year 2018
 Duration (year-month-day) from 2018-04-01   to  2022-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUT PASTEUR FR (PARIS CEDEX 15) coordinator 526˙500.00
2    INSTITUT PASTEUR DE TUNIS TN (TUNIS) participant 783˙000.00
3    PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE BE (ANTWERPEN) participant 211˙500.00
4    GOETEBORGS UNIVERSITET SE (GOETEBORG) participant 112˙500.00
5    UNIVERZITA KARLOVA CZ (PRAHA 1) participant 94˙500.00
6    ACOBIOM FR (GRABELS) participant 22˙500.00
7    INSTITUT PASTEUR D ALGERIE E.P.I.C. DZ (ALGER) partner 0.00
8    INSTITUT PASTEUR D'IRAN IR (TEHRAN) partner 0.00
9    Institut Pasteur Du Maroc MA (Casablanca) partner 0.00

Map

 Project objective

Leishmania causes devastating human diseases – leishmaniases - representing an important public health problem in the Mediterranean basin and declared as emerging diseases in the EU due to climate change and population displacement. The LeiSHield-MATI consortium will for the first time investigate in an integrative fashion the complex parasite-vector-host interplay in cutaneous leishmaniasis affecting Morrocco, Algeria, Tunisia, and Iran (MATI), using field isolates and human clinical samples. The ultimate goal of our project is to identify genetic factors selected during natural infection and to understand how the complex parasite-vector-animal interaction impacts clinical outcome in infected patients. This goal will be achieved through a highly ambitious secondment plan between all partners, and the organization of courses and workshops to train the next generation of scientists generating a long-term impact on the research capacities in endemic areas. Capitalizing on complementary infrastructures of its EU, African and Asian partners and their expertise in molecular parasitology, epidemiology, systems level analyses, bioinformatics, computational biology, immunology, dermatology, field studies, and public health, our project will drive important innovation in clinical research, strengthen capacities in disease endemic regions, inform authorities on control measures, and raise awareness in all partner countries on this emerging EU public health problem. The highly inter-disciplinary and inter-sectorial structure of LeiSHield-MATI, and its powerful integrative and comparative approach is novel in parasitic systems and will drive a unique bio-marker discovery pipeline for the future development of new prognostic and diagnostic tools, as well as novel preventive and therapeutic measures that will ensure long-term collaboration, promote scientific and commercial self-sustainability of its partners, and will have an important impact to improve public health.

 Deliverables

List of deliverables.
Kick-off meeting, a booklet compiling project documentation provided to all partners, a web-based project management platform accessible through the LeiSHield-MATI website Other 2019-06-19 13:18:07

Take a look to the deliverables list in detail:  detailed list of LeiSHield-MATI deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Fariborz Bahrami, Sima Rafati
The LeiSHield-MATI Consortium: An International Project to Understand and Combat Cutaneous Leishmaniasis through Research and Innovation Staff Exchange
published pages: , ISSN: 2345-5349, DOI: 10.29252/jommid.7.3.85
Journal of Medical Microbiology and Infectious Diseases (JOMMID) 2019 Volume 7 Number 4 2020-03-23
2020 Yasaman Taslimia, Christopher Agbajogub, Siggeir Fannar Brynjolfssonc, Nasrin Masoudzadeha, Vahid Mashayekhid, Safoora Gharibzadehe, Malin Östenssonb, Sravya Sowdamini Nakkab, Amir Mizbanif, Sima Rafatia,⁎,1, Ali M. Harandib,g,⁎,1
Profiling inflammatory response in lesions of cutaneous leishmaniasis patients using a non-invasive sampling method combined with a high-throughput protein detection assay.
published pages: , ISSN: 1043-4666, DOI:
Cytokine 2020-03-23

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