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Microrobots SIGNED

Engineering Biohybrid MicroRobots from Magnetic Swimmers and S-layers

Total Cost €

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EC-Contrib. €

0

Partnership

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 Microrobots project word cloud

Explore the words cloud of the Microrobots project. It provides you a very rough idea of what is the project "Microrobots" about.

bmrs    operation    universe    nanoscale    enzymes    robotics    intend    modified    drug    introduce    components    mss    liquid    oscillating    molecules    density    robotic    reassembled    nature    biological    environmental    elegantly    perform    engineering    matrices    will    form    precision    innovative    plethora    bioactivity    surfaces    antibodies    strategy    bacterial    magnetic    genetically    swimmers    engineer    affinity    cargo    combining    linked    wall    nanometre    fight    exploration    microrobots    metallic    equipped    filaments    century    tags    revolutionary    bioactive    stable    archaea    conjugated    scientific    arrays    layers    21st    sls    miniaturise    cell    destination    consist    molecule    conceptual    regular    platform    biohybrid    simply    remote    resilient    protein    inorganic    archaeal    prokaryotic    functional    dimensional    distance    explore    materials    generate    reporters    bespoke    synthetic    environment    biochemical    bacteria    combine    coat    disease    thinkable    nanotechnology    attach    beads    flexibly    applicable    ways    adhesive    media    medicine    microscopic    reassemble   

Project "Microrobots" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF EXETER 

Organization address
address: THE QUEEN'S DRIVE NORTHCOTE HOUSE
city: EXETER
postcode: EX4 4QJ
website: www.ex.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 1˙766˙481 €
 EC max contribution 1˙766˙481 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-STG
 Funding Scheme ERC-STG
 Starting year 2018
 Duration (year-month-day) from 2018-11-01   to  2023-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF EXETER UK (EXETER) coordinator 1˙766˙481.00

Map

 Project objective

Biohybrid MicroRobots (BMRs) are conceptual microscopic robotic devices that combine synthetic and biological components and can be remote controlled to a specific destination, attach to a target and perform a bespoke biochemical operation at nanoscale precision. Within the 5-year Microrobots project, I intend to develop innovative BMRs by combining magnetic swimmers (MSs) with prokaryotic S-layers (SLs). MSs are microscopic devices that consist of two flexibly linked metallic beads with different magnetic properties and can be remote controlled through liquid media, simply by applying oscillating magnetic fields. SLs are highly stable 2-dimensional protein arrays that form resilient cell wall components in archaea and bacteria and can be genetically modified and reassembled on inorganic surfaces. I will introduce affinity tags into selected archaeal and bacterial SLs and reassemble them on the surfaces of MSs. This will coat MSs with unique affinity matrices, on which bioactive molecules can be conjugated at regular arrays, high density and defined distance. Through this strategy, I will generate BMRs that can be equipped with any bioactive functionality provided by nature, such as adhesive filaments, enzymes, antibodies, reporters, drug cargo or any other thinkable functional molecule. The BMRs that I will develop will elegantly miniaturise robotics and enable us to deliver bioactivity at nanometre precision. This will provide a revolutionary platform technology that will be applicable in a plethora of fields, such as medicine, nanotechnology, environmental engineering or scientific exploration and generate a real step change in the ways in which we build new materials, engineer our environment, fight disease and explore the universe in the 21st century.

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The information about "MICROROBOTS" are provided by the European Opendata Portal: CORDIS opendata.

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