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Microrobots SIGNED

Engineering Biohybrid MicroRobots from Magnetic Swimmers and S-layers

Total Cost €

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EC-Contrib. €

0

Partnership

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 Microrobots project word cloud

Explore the words cloud of the Microrobots project. It provides you a very rough idea of what is the project "Microrobots" about.

combining    metallic    oscillating    modified    surfaces    environmental    drug    bacteria    bioactive    equipped    conjugated    linked    enzymes    stable    nanoscale    bespoke    revolutionary    biochemical    magnetic    cell    layers    biological    miniaturise    destination    protein    bioactivity    media    explore    scientific    form    combine    attach    robotics    reporters    operation    swimmers    plethora    liquid    century    exploration    bmrs    density    microrobots    simply    archaeal    innovative    materials    platform    genetically    prokaryotic    robotic    mss    matrices    strategy    applicable    adhesive    will    coat    universe    inorganic    introduce    ways    nanotechnology    conceptual    generate    fight    functional    flexibly    affinity    antibodies    21st    cargo    tags    biohybrid    components    resilient    microscopic    medicine    environment    reassembled    thinkable    molecule    archaea    beads    elegantly    dimensional    regular    precision    engineering    nature    perform    molecules    engineer    sls    reassemble    remote    filaments    distance    arrays    consist    intend    disease    nanometre    wall    synthetic    bacterial   

Project "Microrobots" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF EXETER 

Organization address
address: THE QUEEN'S DRIVE NORTHCOTE HOUSE
city: EXETER
postcode: EX4 4QJ
website: www.ex.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 1˙766˙481 €
 EC max contribution 1˙766˙481 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-STG
 Funding Scheme ERC-STG
 Starting year 2018
 Duration (year-month-day) from 2018-11-01   to  2023-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF EXETER UK (EXETER) coordinator 1˙766˙481.00

Map

 Project objective

Biohybrid MicroRobots (BMRs) are conceptual microscopic robotic devices that combine synthetic and biological components and can be remote controlled to a specific destination, attach to a target and perform a bespoke biochemical operation at nanoscale precision. Within the 5-year Microrobots project, I intend to develop innovative BMRs by combining magnetic swimmers (MSs) with prokaryotic S-layers (SLs). MSs are microscopic devices that consist of two flexibly linked metallic beads with different magnetic properties and can be remote controlled through liquid media, simply by applying oscillating magnetic fields. SLs are highly stable 2-dimensional protein arrays that form resilient cell wall components in archaea and bacteria and can be genetically modified and reassembled on inorganic surfaces. I will introduce affinity tags into selected archaeal and bacterial SLs and reassemble them on the surfaces of MSs. This will coat MSs with unique affinity matrices, on which bioactive molecules can be conjugated at regular arrays, high density and defined distance. Through this strategy, I will generate BMRs that can be equipped with any bioactive functionality provided by nature, such as adhesive filaments, enzymes, antibodies, reporters, drug cargo or any other thinkable functional molecule. The BMRs that I will develop will elegantly miniaturise robotics and enable us to deliver bioactivity at nanometre precision. This will provide a revolutionary platform technology that will be applicable in a plethora of fields, such as medicine, nanotechnology, environmental engineering or scientific exploration and generate a real step change in the ways in which we build new materials, engineer our environment, fight disease and explore the universe in the 21st century.

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The information about "MICROROBOTS" are provided by the European Opendata Portal: CORDIS opendata.

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