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Microrobots SIGNED

Engineering Biohybrid MicroRobots from Magnetic Swimmers and S-layers

Total Cost €

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EC-Contrib. €

0

Partnership

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 Microrobots project word cloud

Explore the words cloud of the Microrobots project. It provides you a very rough idea of what is the project "Microrobots" about.

density    adhesive    reporters    elegantly    attach    liquid    beads    inorganic    thinkable    coat    nanometre    modified    components    introduce    prokaryotic    miniaturise    intend    metallic    drug    revolutionary    conjugated    arrays    synthetic    combine    form    bioactivity    applicable    oscillating    century    reassemble    platform    conceptual    21st    surfaces    exploration    media    archaeal    molecules    stable    destination    tags    explore    linked    cell    magnetic    filaments    layers    robotics    dimensional    medicine    biological    resilient    archaea    simply    bespoke    remote    nanoscale    combining    microrobots    biohybrid    environmental    reassembled    will    generate    consist    enzymes    functional    antibodies    plethora    bacterial    sls    biochemical    bioactive    bmrs    mss    perform    distance    universe    nanotechnology    disease    environment    ways    materials    precision    protein    equipped    nature    flexibly    matrices    swimmers    cargo    robotic    regular    fight    bacteria    scientific    wall    microscopic    engineering    genetically    molecule    operation    engineer    affinity    innovative    strategy   

Project "Microrobots" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF EXETER 

Organization address
address: THE QUEEN'S DRIVE NORTHCOTE HOUSE
city: EXETER
postcode: EX4 4QJ
website: www.ex.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 1˙766˙481 €
 EC max contribution 1˙766˙481 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-STG
 Funding Scheme ERC-STG
 Starting year 2018
 Duration (year-month-day) from 2018-11-01   to  2023-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF EXETER UK (EXETER) coordinator 1˙766˙481.00

Map

 Project objective

Biohybrid MicroRobots (BMRs) are conceptual microscopic robotic devices that combine synthetic and biological components and can be remote controlled to a specific destination, attach to a target and perform a bespoke biochemical operation at nanoscale precision. Within the 5-year Microrobots project, I intend to develop innovative BMRs by combining magnetic swimmers (MSs) with prokaryotic S-layers (SLs). MSs are microscopic devices that consist of two flexibly linked metallic beads with different magnetic properties and can be remote controlled through liquid media, simply by applying oscillating magnetic fields. SLs are highly stable 2-dimensional protein arrays that form resilient cell wall components in archaea and bacteria and can be genetically modified and reassembled on inorganic surfaces. I will introduce affinity tags into selected archaeal and bacterial SLs and reassemble them on the surfaces of MSs. This will coat MSs with unique affinity matrices, on which bioactive molecules can be conjugated at regular arrays, high density and defined distance. Through this strategy, I will generate BMRs that can be equipped with any bioactive functionality provided by nature, such as adhesive filaments, enzymes, antibodies, reporters, drug cargo or any other thinkable functional molecule. The BMRs that I will develop will elegantly miniaturise robotics and enable us to deliver bioactivity at nanometre precision. This will provide a revolutionary platform technology that will be applicable in a plethora of fields, such as medicine, nanotechnology, environmental engineering or scientific exploration and generate a real step change in the ways in which we build new materials, engineer our environment, fight disease and explore the universe in the 21st century.

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The information about "MICROROBOTS" are provided by the European Opendata Portal: CORDIS opendata.

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