Explore the words cloud of the ProtoMet project. It provides you a very rough idea of what is the project "ProtoMet" about.
The following table provides information about the project.
UNIVERSITA DEGLI STUDI DI TRENTO
|Coordinator Country||Italy [IT]|
|Total cost||2˙174˙048 €|
|EC max contribution||2˙174˙048 € (100%)|
1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
|Duration (year-month-day)||from 2018-11-01 to 2022-10-31|
Take a look of project's partnership.
|1||UNIVERSITA DEGLI STUDI DI TRENTO||IT (TRENTO)||coordinator||261˙499.00|
|2||UNIVERSITY COLLEGE LONDON||UK (LONDON)||participant||303˙172.00|
|3||EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH||CH (ZUERICH)||participant||281˙276.00|
|4||CHERRY BIOTECH||FR (RENNES)||participant||274˙802.00|
|6||UNIVERSITE DE STRASBOURG||FR (STRASBOURG)||participant||274˙802.00|
|7||MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV||DE (MUENCHEN)||participant||252˙788.00|
|8||UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA||ES (LEIOA)||participant||250˙904.00|
|9||KUTXAGESTION ZERBITZUAK S.L.U.||ES (DONOSTIA - SAN SEBASTIAN)||partner||0.00|
|10||METALLOPHARM LLC||US (Delaware)||partner||0.00|
|11||NANOVEX BIOTECHNOLOGIES SL||ES (LLANERA)||partner||0.00|
Understanding how prebiotic chemistry gave rise to life as we know it represents one of the greatest enduring mysteries. The complete absence of a historical record requires the collaboration of scientists from different disciplines with access to advanced tools in order to make any meaningful progress. Here, we plan to exploit this tremendous challenge to train a new generation of scientists to think big, but also to work methodically and logically alongside colleagues from academia and industry. Eight Early-Stage Researchers (ESRs) will be recruited to work in laboratories with expertise in systems chemistry, synthetic biology, microfluidics, and science philosophy to develop together a reconstituted protometabolism within compartments consisting of coacervates, vesicles, coacervate containing vesicles, and compartments etched into microfluidic chips. The underlying protometabolism will be composed of triose glycolysis and a reverse citric acid cycle and will be regulated by (metallo)peptide catalysts. Importantly, the protometabolism will support the maintenance of the compartment that houses the protocell. The ESRs that primarily focus on the construction of compartments that mimic protocellular structures will gain firsthand experience in how their formulations could be exploited as drug delivery vehicles through secondments at partner organizations. Similarly, the ESRs that develop (metallo)peptide catalysts will apply their newfound skills to the development of drug molecules through a secondment at a company that specializes in metallodrug formulations. Ultimately, by becoming experts in elucidating the chemical underpinnings of all known living cells, the ESRs will be extremely well positioned to enter a wide variety of research fields from synthetic biology to medicinal chemistry in either industry or academia.
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The information about "PROTOMET" are provided by the European Opendata Portal: CORDIS opendata.