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DirectThalamus SIGNED

How the human thalamus guides navigation and memory: a common coding framework built on direct thalamic recordings

Total Cost €

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EC-Contrib. €

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Partnership

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Project "DirectThalamus" data sheet

The following table provides information about the project.

Coordinator
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN 

Organization address
address: GESCHWISTER SCHOLL PLATZ 1
city: MUENCHEN
postcode: 80539
website: www.uni-muenchen.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 1˙499˙914 €
 EC max contribution 1˙499˙914 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-STG
 Funding Scheme ERC-STG
 Starting year 2019
 Duration (year-month-day) from 2019-07-01   to  2024-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN DE (MUENCHEN) coordinator 1˙499˙914.00

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 Project objective

The thalamus is the major gateway for sensory input to the brain, and, as such, has long been thought of as a mere sensory relay station. But accumulating evidence suggests that it is crucially involved in higher cognitive functions like memory formation and navigation. However, methodological obstacles still impede full understanding of the specific role of thalamus in human cognition. The core objective of DirectThalamus is to provide an advanced oscillatory model of subcortical processing as the neuronal basis of core cognitive functions. To this end, the project will address several key questions with the aim to identify and understand neuronal processing in the thalamus involved in human cognition: How does the human thalamus code and communicate information? And how does this contribute to spatial navigation and the formation and consolidation of memories? Using my unique expertise in innovative methodologies, I will exploit the rare opportunity to record and modulate intracranial electrophysiological activity in the human anterior thalamus. Together with intracranial recordings from the human hippocampus and comparative fMRI data from healthy subjects, these data will be used to test and establish a common coding framework for memory and navigation, highlighting contextual information processing as fundamental thalamic function. By directly recording and stimulating intracranial thalamic activity, DirectThalamus will provide novel and causal insight into thalamic mechanisms underlying core cognitive functions. The project will thereby push the boundaries of the state of the art in cognitive neuroscience towards a comprehensive understanding of cognition. Expanding the prevalent corticocentric focus on cognition to subcortical contributions will inspire new lines of research in fundamental and clinical neuroscience.

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The information about "DIRECTTHALAMUS" are provided by the European Opendata Portal: CORDIS opendata.

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