EU H2020 Project "NANOPSYCH (Neuropsychiatric disorders are a heterogeneous group of mental pathologies..)": description, partecipants, costs and EC-fundings

#	Pagina
attuale pagina	/open-h2020/projects/223784/index.html

NanoPSYCH project word cloud

Explore the words cloud of the NanoPSYCH project. It provides you a very rough idea of what is the project "NanoPSYCH" about.

living privileged preferential integrity functional cellular mediated examination nanoparticle structural underlying therapeutic ecs disrupting ineffective frequently subgroup subgroups diseases central pathophysiology cns pathogenic remained inaccessible prolonged structures monitoring disorders map patient regions biotechnology techniques treatments largely nervous position exploration antibody nanoscopic mode demonstrated combining mechanisms dynamics classification accomplished elucidating molecular appropriate immune biological demand search psychiatric nanotechnology neuropsychiatric organization heterogeneous strategies subject accumulation imaging decades unsolved illness patients precise retention strategy tackle action brain synapses original limitations visualize pathologies recognition extracellular explore influence architecture fueled tools autoantibodies tissue group paramount mental space

Project "NanoPSYCH" data sheet

The following table provides information about the project.

Coordinator	CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS Organization address address: RUE MICHEL ANGE 3 city: PARIS postcode: 75794 website: www.cnrs.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	France [FR]
Total cost	196˙707 €
EC max contribution	196˙707 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2018
Funding Scheme	MSCA-IF-EF-ST
Starting year	2019
Duration (year-month-day)	from 2019-06-01 to 2021-05-31

#	participants	country	role	EC contrib. [€]
1	CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS	FR (PARIS)	coordinator	196˙707.00

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS

FR (PARIS)

coordinator

196˙707.00

Project objective

Neuropsychiatric disorders are a heterogeneous group of mental pathologies that demand prolonged and treatments that are frequently ineffective. Elucidating the cellular and molecular mechanisms underlying these diseases is paramount for a precise classification of subgroups of patient and application of appropriate therapeutic strategies. The role of the immune system in the pathophysiology of neuropsychiatric disorders has been the subject of debate for many decades. However, recent recognition of antibody-mediated central nervous system (CNS) disorders has fueled the search for a subgroup of patients with an antibody-mediated psychiatric illness. CNS autoantibodies have demonstrated to be pathogenic by disrupting the functional or structural integrity of synapses and their study has become an exciting research topic. Several aspects about the mode of action of these pathogenic autoantibodies remain unsolved, such as their accumulation in specific brain regions. An important factor for this preferential retention could be the influence of brain extracellular space (ECS), a component of the brain that has remained largely inaccessible for exploration due to its complex organization and technical limitations for its examination in living tissue. Recent advances in Nanotechnology and Biotechnology have given rise to unique tools to tackle the study of complex biological systems, thus we are now in a privileged position to explore the architecture of the ECS and the dynamics of CNS autoantibodies into brain tissue. The aim of this project is to define how the dynamics of CNS autoantibodies is affected by the ECS architecture in specific brain regions. This goal will be accomplished by using an original strategy combining classical imaging approaches to map the distribution of CNS autoantibodies between different brain structures and nanoparticle monitoring techniques to visualize at the nanoscopic scale the dynamics of CNS autoantibodies and the ECS architecture.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "NANOPSYCH" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "NANOPSYCH" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)