#	Pagina
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Opendata, web and dolomites

InDx SIGNED

InDx - an innovative implant that restores natural motion to patients with thumb base joint arthritis

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

InDx project word cloud

Explore the words cloud of the InDx project. It provides you a very rough idea of what is the project "InDx" about.

movement medical stages first biomechanics natural debilitating commercialization running 51m start loci innovation base population 510k namsa company restore launch estimates designed extensive sme orthopaedics joint ftes market validate organization date disruptive investigations galway small irish implant anatomy prone expertise surgical trl ce international spin germany 5 joints revenues university arthritis clinical accommodate humanitarian national europeans door thumb lags stage socioeconomic cumulative 25 led opening burden human implants functional marking million fundamental prepare healthcare dexterity approval ireland uk treatment endolab 24 commercialisation final impossible medvie usa dressed jar fda substantial dynamic suffers station world approximately causes indx employment months

Project "InDx" data sheet

The following table provides information about the project.

Coordinator	LOCI ORTHOPAEDICS LIMITED Organization address address: UNIT 209 NUIG BUSINESS INNOVATION CENTRE UPPER NEWCASTLE city: GALWAY postcode: H91 V207 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Ireland [IE]
Total cost	3˙633˙125 €
EC max contribution	2˙543˙187 € (70%)
Programme	1. H2020-EU.3. (PRIORITY 'Societal challenges) 2. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
Code Call	H2020-EIC-FTI-2018-2020
Funding Scheme	IA
Starting year	2019
Duration (year-month-day)	from 2019-07-01 to 2021-06-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	LOCI ORTHOPAEDICS LIMITED LOCI ORTHOPAEDICS LIMITED Organization address address: UNIT 209 NUIG BUSINESS INNOVATION CENTRE UPPER NEWCASTLE city: GALWAY postcode: H91 V207 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (GALWAY)	coordinator	1˙746˙500.00
2	NORTH AMERICAN SCIENCE ASSOCIATES LIMITED NORTH AMERICAN SCIENCE ASSOCIATES LIMITED Organization address address: MEDVANCE HOUSE BURN GRANGE, DONCASTER ROAD, BURN city: SELBY postcode: YO8 8LA website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (SELBY)	participant	319˙812.00
3	Medvie Limited Medvie Limited Organization address address: 33 THE MOORINGS city: MALAHIDE postcode: K36 KR72 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (MALAHIDE)	participant	280˙000.00
4	ENDOLAB MECHANICAL ENGINEERING GMBH ENDOLAB MECHANICAL ENGINEERING GMBH Organization address address: AHORNWEG 8 city: RIEDERING postcode: 83083 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (RIEDERING)	participant	196˙875.00

Map

Project objective

The thumb base joint is fundamental for human dexterity and functional activity but is prone to debilitating arthritis. Approximately 5% of the world population suffers from this condition with over 25 million Europeans affected. Simple tasks become impossible such as getting dressed, opening a jar, using a key to open a door. This is certainly a relevant socioeconomic and humanitarian concern, which causes a substantial cost burden on healthcare systems, yet the effective treatment for end-stage thumb base arthritis lags far behind other joints, given challenges of the small, complex anatomy. The InDx project aims to enable the commercialization of the InDx implant, the world’s first implant designed to accommodate the complex biomechanics of the thumb base joint and restore the natural movement of the thumb. The consortium is led by Loci Orthopaedics, a technology-driven SME spin-out company from the National University of Ireland, Galway. The partners include EndoLab in Germany, that has developed a novel dynamic test station for implants, NAMSA in the UK, a leading medical research organization with extensive experience in running international clinical investigations, and Medvie, an Irish based SME with extensive project management, dissemination and commercialization expertise. Together, the consortium have brought the implant to TRL 6 level. As part of the InDx project, the consortium will undertake the final stages of product development and will validate clinical results in a clinical study that will prepare the CE marking and market access. Market launch is planned within 24 months from the project start date, following FDA 510K approval in the USA and CE marking in Europe. The consortium estimates cumulative revenues of €51M within 5 years from the start of commercialisation and an employment growth of 25 FTEs for the consortium partners. The InDx has the potential to be a disruptive innovation in the surgical management of thumb base joint arthritis.

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The information about "INDX" are provided by the European Opendata Portal: CORDIS opendata.

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