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SAND SIGNED

Secretion, Autophagy and their role in Neurodegeneration

Total Cost €

0

EC-Contrib. €

0

Partnership

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 SAND project word cloud

Explore the words cloud of the SAND project. It provides you a very rough idea of what is the project "SAND" about.

stock    microfluidics    academia    patient    human    ipsc    disorders    mortality    leader    consolidate    chemical    made    neurologists    electronic    students    complementary    model    autophagic    zebrafish    secretion    transferrable    stage    beneficiaries    supervision    autophagy    primary    clinically    22    drugs    mouse    protein    training    neurodegeneration    network    translate    custom    framework    drosophila    equip    contains    expertise    alterations    proteostasis    diseases    generation    aging    experts    etn    degradation    diagnost    active    secretory    regulators    translational    strategy    crosstalk    unifying    neuronal    societies    skills    train    fundamental    neurodegenerative    biology    careers    techniques    cellular    database    sorting    combining    imaging    13    explore    lines    repertoire    proteomics    principles    industry    links    models    exhibit    sand    imbalance    screening    organisms    countries    12    intravital    position    causes    cell    scientific    em    academic    neurons   

Project "SAND" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITETET I OSLO 

Organization address
address: PROBLEMVEIEN 5-7
city: OSLO
postcode: 313
website: www.uio.no

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Norway [NO]
 Total cost 4˙156˙404 €
 EC max contribution 4˙156˙404 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2019
 Funding Scheme MSCA-ITN-ETN
 Starting year 2019
 Duration (year-month-day) from 2019-11-01   to  2023-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITETET I OSLO NO (OSLO) coordinator 584˙684.00
2    LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN DE (MUENCHEN) participant 505˙576.00
3    THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE UK (CAMBRIDGE) participant 303˙172.00
4    THE UNIVERSITY OF EDINBURGH UK (EDINBURGH) participant 303˙172.00
5    PRE DIAGNOSTICS AS NO (OSLO) participant 292˙342.00
6    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 281˙982.00
7    ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE CH (LAUSANNE) participant 281˙276.00
8    DARWIN MICROFLUIDICS FR (PARIS) participant 274˙802.00
9    INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE FR (PARIS) participant 274˙802.00
10    CELL STRESS DISCOVERIES LIMITED IE (GALWAY) participant 274˙684.00
11    KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW NL (AMSTERDAM) participant 265˙619.00
12    UNIVERSITA DEGLI STUDI DI MILANO IT (MILANO) participant 261˙499.00
13    LEIBNIZ-INSTITUT FUR ALTERNSFORSCHUNG - FRITZ-LIPMANN-INSTITUT EV (FLI) LEIBNIZ INSTITUTE ON AGING - FRITZ LIPMANN INSTITUTE EV (FLI) DE (JENA) participant 252˙788.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

Neurodegenerative disorders are among the leading causes of mortality and will become more relevant in our continuously aging societies. Most neurodegenerative disorders exhibit alterations in proteostasis, i.e. an imbalance between protein production, sorting and degradation. The secretory and the autophagic pathways are two major regulators of cellular proteostasis and their crosstalk is likely to be relevant for neurodegeneration. Thus, there is a need to train a new generation of early stage researchers that will exploit and translate the fundamental biology principles of autophagy, secretion and their crosstalk in human diseases. Our ETN will explore the links between Secretion, Autophagy and their role in NeuroDegeneration (SAND) and will consolidate the position of Europe as a leader in this field by: (i) providing a framework for training and supervision of students to provide them with a repertoire of transferrable and scientific skills that will equip them for careers in academia and industry. (ii) bringing together leading experts in the fields of autophagy, secretion and neurodegeneration from academia and industry into a consortium that involves 22 participants from 12 countries (12 academic beneficiaries from 13 institutions, 3 industry beneficiaries, 4 non-academic partners and 3 academic partner institutions) (iii) using a unifying strategy such as a common stock of cell lines for screening and a common electronic custom-made database tailored to the needs of our consortium (iv) combining complementary expertise such as systems biology, chemical biology, model organisms (zebrafish, drosophila and mouse models), cellular models (neuronal cell lines, primary neurons and patient-derived iPSC neurons) and techniques (e.g. EM, intravital imaging, proteomics, microfluidics) (v) exploiting the translational potential because the network contains three clinically active neurologists, non-academic partners interested in development of drugs and diagnost

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The information about "SAND" are provided by the European Opendata Portal: CORDIS opendata.

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