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SAND SIGNED

Secretion, Autophagy and their role in Neurodegeneration

Total Cost €

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EC-Contrib. €

0

Partnership

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 SAND project word cloud

Explore the words cloud of the SAND project. It provides you a very rough idea of what is the project "SAND" about.

microfluidics    techniques    causes    aging    leader    framework    neurologists    proteostasis    network    train    drugs    sorting    stock    intravital    lines    careers    made    clinically    combining    em    cell    active    13    secretion    explore    drosophila    diseases    biology    custom    electronic    complementary    22    mouse    neurodegeneration    ipsc    database    position    protein    strategy    alterations    fundamental    repertoire    neuronal    translate    regulators    zebrafish    patient    cellular    translational    supervision    etn    societies    academia    organisms    exhibit    screening    expertise    imaging    stage    industry    training    model    sand    autophagy    consolidate    beneficiaries    crosstalk    equip    countries    transferrable    mortality    primary    human    students    disorders    neurons    generation    chemical    12    imbalance    contains    diagnost    unifying    skills    degradation    neurodegenerative    principles    proteomics    secretory    scientific    experts    links    models    academic    autophagic   

Project "SAND" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITETET I OSLO 

Organization address
address: PROBLEMVEIEN 5-7
city: OSLO
postcode: 313
website: www.uio.no

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Norway [NO]
 Total cost 4˙156˙404 €
 EC max contribution 4˙156˙404 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2019
 Funding Scheme MSCA-ITN-ETN
 Starting year 2019
 Duration (year-month-day) from 2019-11-01   to  2023-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITETET I OSLO NO (OSLO) coordinator 584˙684.00
2    LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN DE (MUENCHEN) participant 505˙576.00
3    THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE UK (CAMBRIDGE) participant 303˙172.00
4    THE UNIVERSITY OF EDINBURGH UK (EDINBURGH) participant 303˙172.00
5    PRE DIAGNOSTICS AS NO (OSLO) participant 292˙342.00
6    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 281˙982.00
7    ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE CH (LAUSANNE) participant 281˙276.00
8    DARWIN MICROFLUIDICS FR (PARIS) participant 274˙802.00
9    INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE FR (PARIS) participant 274˙802.00
10    CELL STRESS DISCOVERIES LIMITED IE (GALWAY) participant 274˙684.00
11    KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW NL (AMSTERDAM) participant 265˙619.00
12    UNIVERSITA DEGLI STUDI DI MILANO IT (MILANO) participant 261˙499.00
13    LEIBNIZ-INSTITUT FUR ALTERNSFORSCHUNG - FRITZ-LIPMANN-INSTITUT EV (FLI) LEIBNIZ INSTITUTE ON AGING - FRITZ LIPMANN INSTITUTE EV (FLI) DE (JENA) participant 252˙788.00

Map

 Project objective

Neurodegenerative disorders are among the leading causes of mortality and will become more relevant in our continuously aging societies. Most neurodegenerative disorders exhibit alterations in proteostasis, i.e. an imbalance between protein production, sorting and degradation. The secretory and the autophagic pathways are two major regulators of cellular proteostasis and their crosstalk is likely to be relevant for neurodegeneration. Thus, there is a need to train a new generation of early stage researchers that will exploit and translate the fundamental biology principles of autophagy, secretion and their crosstalk in human diseases. Our ETN will explore the links between Secretion, Autophagy and their role in NeuroDegeneration (SAND) and will consolidate the position of Europe as a leader in this field by: (i) providing a framework for training and supervision of students to provide them with a repertoire of transferrable and scientific skills that will equip them for careers in academia and industry. (ii) bringing together leading experts in the fields of autophagy, secretion and neurodegeneration from academia and industry into a consortium that involves 22 participants from 12 countries (12 academic beneficiaries from 13 institutions, 3 industry beneficiaries, 4 non-academic partners and 3 academic partner institutions) (iii) using a unifying strategy such as a common stock of cell lines for screening and a common electronic custom-made database tailored to the needs of our consortium (iv) combining complementary expertise such as systems biology, chemical biology, model organisms (zebrafish, drosophila and mouse models), cellular models (neuronal cell lines, primary neurons and patient-derived iPSC neurons) and techniques (e.g. EM, intravital imaging, proteomics, microfluidics) (v) exploiting the translational potential because the network contains three clinically active neurologists, non-academic partners interested in development of drugs and diagnost

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The information about "SAND" are provided by the European Opendata Portal: CORDIS opendata.

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