Bio-TUNE SIGNED
Fine tune of cellular behavior: multifunctional materials for medical implants
Total Cost €
0EC-Contrib. €
0Partnership
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0Bio-TUNE project word cloud
Explore the words cloud of the Bio-TUNE project. It provides you a very rough idea of what is the project "Bio-TUNE" about.
Project "Bio-TUNE" data sheet
The following table provides information about the project.
| Coordinator |
UNIVERSITAT POLITECNICA DE CATALUNYA
Organization address contact info |
| Coordinator Country | Spain [ES] |
| Total cost | 814˙200 € |
| EC max contribution | 814˙200 € (100%) |
| Programme |
1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge) |
| Code Call | H2020-MSCA-RISE-2019 |
| Funding Scheme | MSCA-RISE |
| Starting year | 2020 |
| Duration (year-month-day) | from 2020-01-01 to 2023-12-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | UNIVERSITAT POLITECNICA DE CATALUNYA | ES (BARCELONA) | coordinator | 216˙200.00 |
| 2 | UNIVERSITA DEGLI STUDI DI CAMERINO | IT (CAMERINO) | participant | 211˙600.00 |
| 3 | UNIVERSITY OF BRISTOL | UK (BRISTOL) | participant | 110˙400.00 |
| 4 | UNIVERSITY OF GLASGOW | UK (GLASGOW) | participant | 110˙400.00 |
| 5 | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV | DE (MUENCHEN) | participant | 87˙400.00 |
| 6 | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE | FR (PARIS) | participant | 78˙200.00 |
| 7 | GADJAH MADA UNIVERSITY | ID (YOGYAKARTA) | partner | 0.00 |
| 8 | UNIVERSIDAD NACIONAL DE GENERAL SAN MARTIN | AR (SAN MARTIN BUENOS AIRES) | partner | 0.00 |
| 9 | UNIVERSIDAD PERUANA DE CIENCIAS APLICADAS SAC | PE (LIMA) | partner | 0.00 |
| 10 | UNIVERSITI SAINS MALAYSIA* | MY (PENANG) | partner | 0.00 |
Map
Project objective
Bio-TUNE aims to develop innovative multifunctional materials to produce a new generation of medical implants with cell instructive and antibacterial potential.
In biomaterials science, it is well accepted that implant biointegration with surrounding tissues is a major goal. However, implant surfaces that facilitate cell adhesion, may also favor colonization of bacterial cells. Infection of biomaterials and subsequent biofilm formation can be catastrophic and significantly reduce patient quality of life, representing an emerging concern in healthcare.
On the other hand, research efforts devoted to inhibit bacterial colonization are frequently related to cytotoxic agents or treatments that do not positively affect host tissues. Hence, ideally, to enhance the long-term success of medical implants, biomaterial surfaces should reduce bacterial colonization levels without compromising the physiological functions of eukaryotic cells. Yet, the majority of current approaches tend to only focus on either improving cell adhesion or preventing bacterial infection but rarely explore a combined effect.
In Bio-TUNE we focus on multifunctional coatings to simultaneously address and mitigate both these problems. Thus, Bio-TUNE introduces a new mindset and different paradigms in the development of biomaterials to respond to unmet clinical needs.
Bio-TUNE ambitions to 1) Study and understand the interaction of eukaryotic cells with bacteria at the biophysical and biomolecular level; 2) To develop cell instructive and antibacterial surfaces via biochemical and topographical approaches; 3) Transfer this technology to medical implants.
We seek to decipher the mechanistic of eukaryotic and bacterial cell competition, generate new selective and multi-potential coatings and topographically-active patterns, and their technological transfer leading to a generation of advanced biomimetic materials for tissue regeneration and personalized medicine.
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The information about "BIO-TUNE" are provided by the European Opendata Portal: CORDIS opendata.