Opendata, web and dolomites

OMIT SIGNED

The role of microbial Oxylipins in the MIcrobe-hosT dialogue

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 OMIT project word cloud

Explore the words cloud of the OMIT project. It provides you a very rough idea of what is the project "OMIT" about.

comprising    culture    chemical    contributions    moxy    cell    latter    biochemical    roles    migration    validated    co    expression    biofilm    appreciated    receive    gene    oxidation    platforms    signals    leadership    chemotaxis    functions    health    characterised    continue    fellowships    she    disease    faecal    samples    host    perceived    maturity    mechanistic    liquid    secondment    oxylipin    society    reactions    function    independent    experiments    discovery    regulators    competencies    contribution    bacterial    waters    training    ultra    microbially    healthy    acids    docosanoids    gained    implicit    chromatography    quality    supernatants    uk    signalling    volunteers    octadecanoids    man    liberated    significantly    microbial    patients    analysed    proliferation    immune    spectrometry    ms    performed    microbiome    human    hoxy    fatty    diversity    headquarters    bacteria    additional    performance    oxlipin    msca    economy    inflammation    assays    scientific    building    eicosanoids    oxylipins    mass    line    crohns    professional    precursor    microbe    career    platform    biobanked    profiling    dialogue    add    omit    vitro    interactions    humans    incubation    examine   

Project "OMIT" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK 

Organization address
address: WESTERN ROAD
city: Cork
postcode: T12 YN60
website: www.ucc.ie

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Total cost 196˙590 €
 EC max contribution 196˙590 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-RI
 Starting year 2020
 Duration (year-month-day) from 2020-11-09   to  2022-11-08

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK IE (Cork) coordinator 196˙590.00

Map

 Project objective

OMIT aims to examine the role of microbial Oxylipins in the MIcrobiome:hosT dialogue. Oxylipins liberated from the oxidation of fatty acids are appreciated as key chemical signals perceived by both microbe and man. Human oxylipins (hOXY), comprising eicosanoids, docosanoids and octadecanoids are well characterised; they are implicit in many biochemical and signalling pathways in humans, including cell migration, proliferation, chemotaxis, immune reactions and most importantly, they are key regulators of inflammation. However, the diversity, functions, impact and mechanistic roles of microbially derived oxylipins (mOXY) are not well understood. State-of-the-art ultra-performance liquid chromatography-mass spectrometry (MS) platforms (secondment at Waters MS Headquarters, UK) will be developed and validated for oxylipin analysis in faecal samples and bacterial supernatants derived from co-incubation experiments (i.e. bacteria and oxlipin precursor). The latter will facilitate the discovery of novel mOXY. Additional bacterial biofilm assays will be performed to examine the role of mOXY in microbe-microbe interactions. To determine the contribution of mOXY in health and disease, biobanked samples from healthy volunteers and Crohns disease patients will be analysed. In vitro cell culture experiments and gene expression profiling will determine the function of mOXY in microbe-host interactions. During this project, the applicant will receive high quality training through research that will significantly improve scientific knowledge and provide a strong platform for building an independent research career. In line with the Work Programme for the MSCA fellowships, the knowledge and competencies gained by the applicant will add to developing her potential to achieve professional maturity and leadership in the field so that she may continue to make significant contributions to society and the economy.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "OMIT" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "OMIT" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

RAMBEA (2019)

Realistic Assessment of Historical Masonry Bridges under Extreme Environmental Actions

Read More  

IRF4 Degradation (2019)

Using a novel protein degradation approach to uncover IRF4-regulated genes in plasma cells

Read More  

PROSPER (2019)

Politics of Rulemaking, Orchestration of Standards, and Private Economic Regulations

Read More