TRANSFORMERSURFACES

Dynamic Libraries for the Synthesis of New Multifunctional Silica Striped Nanoparticles

 Coordinatore ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE 

 Organization address address: BATIMENT CE 3316 STATION 1
city: LAUSANNE
postcode: 1015

contact info
Titolo: Prof.
Nome: Francesco
Cognome: Stellacci
Email: send email
Telefono: +41 21 693 78 72
Fax: +41 21 693 52 70

 Nazionalità Coordinatore Switzerland [CH]
 Totale costo 184˙709 €
 EC contributo 184˙709 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2011-IEF
 Funding Scheme MC-IEF
 Anno di inizio 2012
 Periodo (anno-mese-giorno) 2012-07-01   -   2014-06-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE

 Organization address address: BATIMENT CE 3316 STATION 1
city: LAUSANNE
postcode: 1015

contact info
Titolo: Prof.
Nome: Francesco
Cognome: Stellacci
Email: send email
Telefono: +41 21 693 78 72
Fax: +41 21 693 52 70

CH (LAUSANNE) coordinator 184˙709.40

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

nanoparticles    striped    surface    toxic    ligands    reversibly    silica   

 Obiettivo del progetto (Objective)

'The last decades have been characterized by a great interest on nanotechnology applied to biology and medicine. Nanoparticles play a leading role thanks to their novel properties relative to their bulk material counterparts. Within TransformerSurfaces the training-through-research is targeted at synthesizing silica nanoparticles, coated with a molecular monolayer that can in turn be reversibly functionalized with different ligands following the principles of the Dynamic Combinatorial Chemistry (DCC). The goal is to obtain a new surface suitable for a larger range of possible functionalization. In particular, taking inspiration from the striped gold nanoparticles that have been recently discovered in the group, this project is targeted to functionalize the outermost coating of the silica nanoparticles with higher order patterns, especially stripes. In fact, these ‘striped’ nanoparticles are capable of penetrating cell membranes without porating (creating transient holes associated with leakage and cytotoxicity) as viruses do. Additionally by combining the biocompatibility of silica with the low toxic effect given by the optimization of the ligands arrangement on the surface, we aim to erase the toxicity of nanoparticles.'

Introduzione (Teaser)

Functionalising nanoparticles (NPs) to reversibly bind ligands paves the way to biomedical applications such as drug delivery. Scientists made major progress with inexpensive, inert and non-toxic silica to support the effort.

Altri progetti dello stesso programma (FP7-PEOPLE)

IXMI (2013)

Improving the eXperience of musicians and spectators with digital Musical Instruments using 3D interfaces and mixed-reality technologies

Read More  

MICROIPB (2011)

Microbial activities of the sulfur cycle in the subsurface of the Iberian Pyritic Belt

Read More  

UNITE (2010)

UPM - Marie Curie International Mobility Programme

Read More