INTENSO

"Gaining Productivity, Cost Efficiency and Sustainability in the Downstreaming Processing of Bio Products by novel Integration and Intensification strategies"

 Coordinatore JACOBS UNIVERSITY BREMEN GGMBH 

 Organization address address: Campus Ring 1
city: BREMEN
postcode: 28759

contact info
Titolo: Mr.
Nome: Ronald
Cognome: Kieschnick
Email: send email
Telefono: +49 421 2004515

 Nazionalità Coordinatore Germany [DE]
 Totale costo 7˙114˙674 €
 EC contributo 5˙260˙960 €
 Programma FP7-KBBE
Specific Programme "Cooperation": Food, Agriculture and Biotechnology
 Code Call FP7-KBBE-2012-6-singlestage
 Funding Scheme CP-TP
 Anno di inizio 2012
 Periodo (anno-mese-giorno) 2012-08-01   -   2017-01-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    JACOBS UNIVERSITY BREMEN GGMBH

 Organization address address: Campus Ring 1
city: BREMEN
postcode: 28759

contact info
Titolo: Mr.
Nome: Ronald
Cognome: Kieschnick
Email: send email
Telefono: +49 421 2004515

DE (BREMEN) coordinator 667˙860.00
2    DSM BIOLOGICS COMPANY BV

 Organization address address: ZUIDERWEG 72/2
city: GRONINGEN
postcode: 9744 AP

contact info
Titolo: Mr.
Nome: Rolf
Cognome: Douwenga
Email: send email
Telefono: 31613400623

NL (GRONINGEN) participant 419˙196.00
3    INFOCONSULT GESELLSCHAFT FUR INFORMATIONSTECHNIK MBH

 Organization address address: ANNE CONWAY STRASSE 4
city: BREMEN
postcode: 28359

contact info
Titolo: Dr.
Nome: Peter
Cognome: Knackfuß
Email: send email
Telefono: +49 421 3306480

DE (BREMEN) participant 397˙623.00
4    UNIVERSITAET FUER BODENKULTUR WIEN

 Organization address address: Gregor Mendel Strasse 33
city: WIEN
postcode: 1180

contact info
Titolo: Prof.
Nome: Alois
Cognome: Jungbauer
Email: send email
Telefono: +43147654 6226
Fax: 431477000000

AT (WIEN) participant 333˙380.00
5    VIRTUALPIE LTD

 Organization address address: THE FLUID ENGINEERING CENTRE
city: CRANFIELD
postcode: MK43 0AJ

contact info
Titolo: Mr.
Nome: Mike
Cognome: Butcher
Email: send email
Telefono: 447973000000
Fax: 441235000000

UK (CRANFIELD) participant 312˙068.00
6    INSTITUTO SUPERIOR TECNICO

 Organization address address: Avenida Rovisco Pais 1
city: LISBOA
postcode: 1049-001

contact info
Titolo: Prof.
Nome: Raquel
Cognome: Aires-Barros
Email: send email
Telefono: +351 218419134
Fax: +351 218419062

PT (LISBOA) participant 305˙503.00
7    GENERI BIOTECH

 Organization address address: Machkova 587
city: Hradec Kralove
postcode: 50011

contact info
Titolo: Dr.
Nome: Martin
Cognome: Martin
Email: send email
Telefono: +420 495056151

CZ (Hradec Kralove) participant 300˙600.00
8    SOFIISKI UNIVERSITET SVETI KLIMENT OHRIDSKI

 Organization address address: Tsar Osvoboditel Blvd. 15
city: SOFIA
postcode: 1504

contact info
Titolo: Prof.
Nome: Valentina
Cognome: Ganeva
Email: send email
Telefono: +35928167 237

BG (SOFIA) participant 297˙620.00
9    ERA BIOTECH

 Organization address address: CALLE BALDIRI REIXAC 15-21
city: BARCELONA
postcode: 8028

contact info
Titolo: Dr.
Nome: Blanca
Cognome: Llompart
Email: send email
Telefono: 34934039785

ES (BARCELONA) participant 295˙060.00
10    ETHRIS GMBH

 Organization address address: LOCHHAMER STRASSE 11
city: MARTINSRIED PLANEGG
postcode: 82152

contact info
Titolo: Dr.
Nome: Carsten
Cognome: Rudolph
Email: send email
Telefono: +49 8152 9299 7331
Fax: +49 8152 9299 7339

DE (MARTINSRIED PLANEGG) participant 295˙028.00
11    PROXCYS

 Organization address address: KAMPWEG 2
city: EMMEN
postcode: 7812 BS

contact info
Titolo: Mr.
Nome: Marcel
Cognome: Raedts
Email: send email
Telefono: +31 591 677 447
Fax: +31 591 677 448

NL (EMMEN) participant 294˙780.00
12    BIOMEDAL SL

 Organization address address: CUBA 1-1B
city: SEVILLA
postcode: 41100

contact info
Titolo: Mr.
Nome: Cebolla Ramirez
Cognome: Angel
Email: send email
Telefono: +34 954081276

ES (SEVILLA) participant 291˙400.00
13    CHIPRO GMBH

 Organization address address: ANNE-CONWAY-STRASSE 1
city: BREMEN
postcode: 28359

contact info
Titolo: Dr.
Nome: Sebastian
Cognome: Thiem
Email: send email
Telefono: +49 421 27656924

DE (BREMEN) participant 290˙026.00
14    BIA SEPARATIONS DOO

 Organization address address: MIRCE 21
city: AJDOVSCINA
postcode: 5270

contact info
Titolo: Dr.
Nome: Nika
Cognome: Lendero Krajnc
Email: send email
Telefono: +386 59 699 500
Fax: +386 59 699 599

SI (AJDOVSCINA) participant 288˙596.00
15    ICOSAGEN AS

 Organization address address: NOORUSE 9
city: TARTU
postcode: 50411

contact info
Titolo: Prof.
Nome: Mart
Cognome: Ustav
Email: send email
Telefono: +372 737 7070

EE (TARTU) participant 249˙460.00
16    UNIVERSIDAD NACIONAL DE QUILMES

 Organization address address: ROQUE SAENZ PENA 352
city: BERNAL
postcode: B1876BXD

contact info
Titolo: Prof.
Nome: Mariano
Cognome: Grasselli
Email: send email
Telefono: +54114365 5624
Fax: +54 11 4365 7132

AR (BERNAL) participant 222˙760.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

classes    molecules    particles    pipelines    inefficiencies    purification    bottlenecks    manufacturing    intensification    industrial    biological    mentioned    involves    intenso    recovery    fermentation    downstream    sustainable    environmental    biopharmaceuticals    integration    bioproducts    virus    science    strategy    technologies    capture    nano    cell    bio    techniques    bioprocessing    introduce    critical   

 Obiettivo del progetto (Objective)

'The European Life science and chemical industries increasingly depend on effi-cient, sustainable, and cost-effective bioprocessing platforms to remain competi-tive. A critical assessment of current bottlenecks during (bio) manufacturing clearly indicates that the recovery and purification of biologicals in large scale in responsible for many inefficiencies.

INTENSO proposes an evaluation of the current situation of the downstream processing scenario with the aim of identifying inefficiencies and concomitantly introduce a debottlenecking overarching strategy. The later will be build up on the basis of a multidisciplinary approach, which considers opportunities to im-prove the process technology and underlying chemistry / biology and materials science at the same time. INTENSO will work alongside 4 technological axes, targeting promising and up-coming technologies and tailoring such technologies to the manufacturing of various classes of (bio) products. Intensification of individual unit operations and global process integration, as well as, dovetailing with fermentation / cell cultivation will be employed to the mentioned end.

INTENSO will target new classes of (bio) products like Monoclonal Antibodies (Mabs), pDNA (e.g. for genetic vaccination), Virus Like Particles (VLP) or nano-plexes. All the mentioned new products are part of most industrial R&D pipelines and offer an excellent opportunity to introduce innovative bioprocessing.

The results of the project are expected to contribute to the understanding of current industrial downstream processing practice, to the definition and alleviation of current inefficiencies, to the development and / or implementation of novel technologies, and to more efficient / sustainable and cost effective (bio) manufacturing. Various technologies will be studied utilizing a nano-to-process strategy so as to introduce integration / intensification during bioprocessing.'

Introduzione (Teaser)

Researchers are revealing key areas for improvement in the manufacture of bioproducts.

Descrizione progetto (Article)

Biomanufacturing involves converting biological resources into products like biopharmaceuticals, enzymes, biofuels and vaccines. A critical and expensive step is recovering highly pure samples efficiently from the biological source.

The EU-funded http://intensoproject.eu/ (INTENSO) project was set up to identify bottlenecks in these downstream processing methods, and to find solutions applicable to a wide range of products. Researchers are concentrating on bioproducts that form part of most industrial research and development pipelines in order to reduce inefficiencies and costs.

They placed emphasis on protein purification from cell or fermentation cultures, developing techniques to separate or capture desired proteins from other cell components. These techniques are economical, can be scaled up and may be applied to several fields, including the recovery of biopharmaceuticals, environmental remediation and enzyme purification.

Another focus point is the capture of large molecules such as virus particles. These have traditionally been hard to purify, but INTENSO researchers are investigating two potential methods.

The first involves separating molecules based on size using porous rod structures known as monolithic columns. The second, earmarked for vaccine production, makes use of disposable cartridges to which large molecules are adsorbed directly from crude extracts.

For these technologies to have a sustainable effect on all forms of biotechnology, the INTENSO team will factor in economic, environmental and social impacts. They will consider legal constraints, government policies, operating costs and profitability, as well as the effects on the environment and the technology's end users.

Altri progetti dello stesso programma (FP7-KBBE)

SEA-ON-A-CHIP (2013)

Real time monitoring of SEA contaminants by an autonomous Lab-on-a-chip biosensor

Read More  

SYMBIOSIS-EU (2008)

"Scientific sYnergisM of nano-Bio-Info-cOgni Science for an Integrated system to monitor meat quality and Safety during production, storage, and distribution in EU"

Read More  

EUPHRESCO (2011)

EUROPEAN PHYTOSANITARY RESEARCH COORDINATION II

Read More