EXPOSOMICS
Enhanced exposure assessment and omic profiling for high priority environmental exposures in Europe
| Coordinatore | IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE
Organization address
address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD contact info |
| Nazionalità Coordinatore | United Kingdom [UK] |
| Totale costo | 11˙649˙540 € |
| EC contributo | 8˙748˙628 € |
| Programma | FP7-ENVIRONMENT
Specific Programme "Cooperation": Environment (including Climate Change) |
| Code Call | FP7-ENV-2012-two-stage |
| Funding Scheme | CP |
| Anno di inizio | 2012 |
| Periodo (anno-mese-giorno) | 2012-11-01 - 2016-10-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE
Organization address
address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD contact info |
UK (LONDON) | coordinator | 1˙246˙767.40 |
| 2 |
UNIVERSITEIT MAASTRICHT
Organization address
address: Minderbroedersberg 4-6 contact info |
NL (MAASTRICHT) | participant | 1˙444˙272.00 |
| 3 |
UNIVERSITEIT UTRECHT
Organization address
address: Heidelberglaan 8 contact info |
NL (UTRECHT) | participant | 1˙361˙304.00 |
| 4 |
FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL
Organization address
address: Calle Doctor Aiguader 88 contact info |
ES (BARCELONA) | participant | 1˙185˙106.00 |
| 5 |
CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER
Organization address
address: Cours Albert-Thomas 150 contact info |
FR (LYON CEDEX 08) | participant | 1˙130˙151.60 |
| 6 |
KING'S COLLEGE LONDON
Organization address
address: Strand contact info |
UK (LONDON) | participant | 632˙318.00 |
| 7 |
SCHWEIZERISCHES TROPEN- UND PUBLIC HEALTH-INSTITUT
Organization address
address: SOCINSTRASSE 57 contact info |
CH (Basel) | participant | 482˙417.00 |
| 8 |
GENEDATA AG
Organization address
address: MARGARETHENSTRASSE 38 contact info |
CH (BASEL) | participant | 461˙380.00 |
| 9 |
ATEKNEA SOLUTIONS CATALONIA, SA
Organization address
address: CALLE VICTOR PRADERA 45 contact info |
ES (CORNELLA DE LLOBREGAT BARCELONA) | participant | 259˙272.00 |
| 10 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Organization address
address: "FRANKLIN STREET 1111, 12 FLOOR" contact info |
US (OAKLAND CA) | participant | 245˙450.80 |
| 11 |
ETHNIKO IDRYMA EREVNON
Organization address
address: Vassileos Constantinou Avenue 48 contact info |
EL (ATHENS) | participant | 222˙360.00 |
| 12 |
UNIVERSITY OF BRISTOL
Organization address
address: TYNDALL AVENUE SENATE HOUSE contact info |
UK (BRISTOL) | participant | 77˙830.00 |
| 13 |
UNIVERSITEIT HASSELT
Organization address
address: MARTELARENLAAN 42 contact info |
BE (Hasselt) | participant | 0.00 |
Mappa
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Obiettivo del progetto (Objective)
'This project aims to predict individual disease risk related to the environment, by characterizing the external and internal exposome for common exposures (air and drinking water contaminants) during critical periods of life, including in utero. A large amount of health data is now available from longitudinal cohorts in both children and adults, with detailed information on risk factors, confounders and outcomes, but these are not well linked with environmental exposure data. The exposome concept refers to the totality of environmental exposures from conception onwards, and is a novel approach to studying the role of the environment in human disease. This project will move the field forward by utilising data on individual external exposome (including sensors, smartphones, geo-referencing, satellites), and omic profiles in an agnostic search for new and integrated biomarkers. These tools will be applied in both experimental short-term studies and long-term longitudinal studies in humans. The ultimate goal is to use the new tools in risk assessment and in the estimation of the burden of environmental disease. The involvement of two SMEs, one specialized in sensors and smartphone development, the other in complex data integration, will increase the chances of a successful impact on European Public Health. This multidisciplinary proposal combines: • development of a general framework for the systematic measurement of the internal and external exposome in Europe in relation to air and water contamination, as a way to reduce uncertainty in risk assessment and to address the effects of mixtures and complex exposures; • evaluation of health outcomes and key physiological changes in short-term studies (including a randomized trial) and life-course studies with a large amount of information on diet, physical activity and anthropometry; • evaluation of the burden of disease in the European population, based on state-of-the-art assessment of population exposures.'
Introduzione (Teaser)
People are exposed to many pollutants over a lifetime. An EU-funded project aims to measure the effect of these exposures on chronic diseases.