SEMI-NUC

Prospective cohort study of residents near the Semipalatinsk nuclear test site - feasibility

 Coordinatore CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER 

 Organization address address: Cours Albert-Thomas 150
city: LYON CEDEX 08
postcode: 69372

contact info
Titolo: Dr.
Nome: Olaf
Cognome: Kelm
Email: send email
Telefono: +33 4 7273 8494
Fax: +33 4 7273 8394

 Nazionalità Coordinatore France [FR]
 Totale costo 1˙449˙712 €
 EC contributo 945˙000 €
 Programma FP7-EURATOM-FISSION
EURATOM: Nuclear fission and radiation protection
 Code Call FP7-Fission-2012
 Funding Scheme CSA-SA
 Anno di inizio 2013
 Periodo (anno-mese-giorno) 2013-04-01   -   2016-03-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER

 Organization address address: Cours Albert-Thomas 150
city: LYON CEDEX 08
postcode: 69372

contact info
Titolo: Dr.
Nome: Olaf
Cognome: Kelm
Email: send email
Telefono: +33 4 7273 8494
Fax: +33 4 7273 8394

FR (LYON CEDEX 08) coordinator 306˙702.00
2    NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES

 Organization address address: "9-1 ANAGAWA 4-CHOME, INAGE-KU, CHIBA-SHI"
city: CHIBA
postcode: 263-8555

contact info
Titolo: Dr.
Nome: Kazuo
Cognome: Sakai
Email: send email
Telefono: 81432066290
Fax: 81432064134

JP (CHIBA) participant 271˙780.00
3    INSTITUTE OF RADIATION SAFETY AND ECOLOGY OF THE NATIONAL NUCLEAR CENTER OF KAZAKHSTAN

 Organization address address: KRASNOARMEYSKAYA 2
city: KURCHATOV
postcode: 71100

contact info
Titolo: Mr.
Nome: Sergey
Cognome: Lukashenko
Email: send email
Telefono: +7 7225 123413
Fax: +7 7225 122806

KZ (KURCHATOV) participant 156˙478.00
4    MEDICAL RADIOLOGICAL RESEARCH CENTRE - RUSSIAN ACADEMY OF MEDICAL SCIENCES

 Organization address address: Koroleva Street 4
city: OBNINSK
postcode: 249020

contact info
Titolo: Prof.
Nome: Andrei
Cognome: Kaprin
Email: send email
Telefono: 74959561439
Fax: 74959561440

RU (OBNINSK) participant 60˙000.00
5    STATE RESEARCH CENTER - BURNASYAN FEDERAL MEDICAL BIOPHYSICAL CENTER OF FEDERAL MEDICAL BIOLOGICAL AGENCY

 Organization address address: Ul. Zhivopisnaya 46
city: Moscow
postcode: 123182

contact info
Nome: Aleksey
Cognome: Kolpakov
Email: send email
Telefono: 74991908600
Fax: 74991908525

RU (Moscow) participant 60˙000.00
6    BUNDESAMT FUER STRAHLENSCHUTZ

 Organization address address: Willy-Brandt-Strasse 5
city: SALZGITTER
postcode: 38226

contact info
Nome: Susan
Cognome: Fischer
Email: send email
Telefono: +49 30 18 333 1537

DE (SALZGITTER) participant 50˙450.00
7    SCIENTIFIC RESEARCH INSTITUTE OF RADIATION MEDICINE AND ECOLOGY NIIRME

 Organization address address: GANGARINA 258
city: SEMIPATATINSK
postcode: 490007

contact info
Titolo: Dr.
Nome: Talgat
Cognome: Muldagaliev
Email: send email
Telefono: 7222645649
Fax: 7222645649

KZ (SEMIPATATINSK) participant 39˙590.00
8    NORWEGIAN RADIATION PROTECTION AUTHORITY

 Organization address address: GRINI NAERINGSPARK 13
city: OSTERAAS
postcode: 1332

contact info
Titolo: Mrs.
Nome: Astrid
Cognome: Liland
Email: send email
Telefono: 4767162538
Fax: 4767147407

NO (OSTERAAS) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

nuclear    outcomes    cohort    kazakhstan    populations    semipalatinsk    site    moderate    radiation    health    data    cancer    mechanisms    scientists    chronic    epidemiological    feasibility    dose    cohorts    doses    identification   

 Obiettivo del progetto (Objective)

'The health effects of exposures to fallout from Soviet nuclear weapons testing among the residents living nearby the Semipalatinsk nuclear test site in Kazakhstan are not well investigated. There are reports with contradicting results coming from the studies conducted on two independent cohorts: “historical” and “new”. Both use different control groups and dosimetric methods. The two cohorts have a high probability of including the same individuals. There is a need to investigate possibilities to merge them in order to avoid duplication of efforts and resources for future studies of the health effects in these populations. The main objectives of our feasibility study include: • developing and testing mechanisms for identification of cohort members in the two cohorts; • identification and testing of data linkage mechanisms; • determination of the outcomes that can be studied (cancer and non-cancer diseases); • setting up and testing procedures for follow-up; • identification of case ascertainment mechanisms and sources, depending on the outcome; • characterization and validation of dose assessment methods used in the two cohorts; • investigation of the feasibility to collect data on confounding factors; • assessing the availability of biological samples and their potential use in the future. The project will bring together scientists from Europe, Kazakhstan and Japan with the aim of developing a proposal for a future prospective full scale epidemiological study to address the dose-effect relationship for both cancer and non-cancer effects from low to moderate chronic doses, if the feasibility is demonstrated. To achieve the overall objective it is proposed to set-up a consortium that have considerable experience in epidemiological studies on populations residing around the Semipalatinsk nuclear test site and/or who have been extensively involved in the low dose risk research. The group will include European and international scientists with expertise in epidemiology, dosimetry, radiation biology and clinical medicine. At the end of the project, a detailed report based on the results of the work conducted will be developed, critically reviewed by the External Advisory Board and recommendations for future research needs will be made, if feasible. Other populations exposed to low to moderate dose radiation like in Fukushima or elsewhere can benefit from the outcomes of studying the unique Semipalatinsk cohort and the results will contribute to a better understanding and quantification of radiation risks for low to moderate chronic doses. The proposed project is in line with the Strategic Research Agenda of MELODI.'

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